Award Data

Abstract: “sHLA Protein Chip” The class I [A, B, C] and class II HLA proteins [DRB1, DQ, DP] comprise the heart of the inducible human immune system. For organ, marrow and stem cell transplantation, the development of serum-born antibodies against one or more of those many HLA proteins comprises the best and earliest test for transplant rejection. Because of the enormous medical importance of ...

Circular RNAs (circRNAs) are a novel class of non-coding RNAs that are an abundant component of the epitranscriptome. Putative functions of circRNAs, include miRNA sequestration, RNA-binding protein scaffolding, mRNA trapping, and protein translation regulation. Deregulation in one or more of these roles has been linked to several types of cancer, including pancreatic cancer, basal cell carcinoma, ...

ORBIS proposes to Address SBIR DLA171-002 by developing efficient and effective processes to reverse engineer RPPOB Candidate Items. ORBIS has a wealth of experience in supporting DoD systems and components and is well suited to addressing the backlog of unsupported equipment .

RDRTec’s RACAS’s Active Element Scanned Array design approach to meet collision avoidance performance, SWaPC and cost goals utilizes RDRTec’s unique array topology.RDRTec has been developing, enhancing, and extending the Common Radar Airborne Collision Avoidance System (C-RACAS) and associated modeling and simulation tools for non-cooperative conflict avoidance for both Triton and Fire Scout ...

MCA is an innovative combination of maritime feature extraction algorithms, target database, and user interface that aid operators in rapidly and effectively classify maritime targets. To date MCA has exploited scattering features that are the result of scattering off static (non-rotating) ship structure returns as well as wake returns in Inverse Synthetic Aperture Radar (ISAR) and High Range Reso ...

The broader impact/commercial potential of this project will be to help control nutrient contaminants in soil and water for the benefit of the world?s population, by providing sustainable access to safe drinking water. The estimated national economic cost of nitrogen pollution in drinking water is $19 billion annually, while the cost to freshwater ecosystems is $78 billion per year. Traditional wa ...

This STTR Phase I project will undertake the development of iron coordination complexes as alternatives for gadolinium contrast agents which are currently used in clinical MRI diagnostic exams. New MRI contrast agents are needed to serve the segment of the population who cannot tolerate Gd(III) agents. This includes patients with kidney disease and those who have frequent MRI scans and may accumul ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project will result from a direct benefit to the energy sector of the U.S. economy, since seismic exploration will play an increasingly important role in meeting increasing energy demands and maintaining healthy oil and gas output. The goal of this project is to develop a software package for automate ...

The broader impact/commercial potential of this project is to vastly improve broadband access to the home across The Nation using true full duplex technology. By bringing full duplex communications to wireline and wireless systems, this proposed effort aims to improve connectivity, enhance coverage and enable new applications for both dense urban and sparse rural communities. This effort benefits ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project will serve two complementary unmet market needs by: (1) accelerating the evaporation rate of brine ponds and enhancing salt production efficiency by 2-3 times; (2) condensing the moisture evaporated from contaminated/salty water so that one can obtain clean drinking water with n consumption of ...