Award Data

ABSTRACTThe global death toll from Malaria is estimated to be upwards ofpeople each yearwith more thanchildren succumbing every dayPlasmodium falciparumPfSporozoiteSPZbased vaccines are the only intervention in humansproven to induce robusthigh levelandgtand long lastingat leastmonthsprotective efficacy against malariaforming the basis of Sanaria s unique technology platform of asepticpurifiedcryo ...

Globalization and digitization have been driving the recent economic growth at the expense of raising the risk level in the supply chain related to fraud, security, and safety, while current practice of supply chain management and risk assessment is lagging far behind. Therefore, commercial industries and government agencies are seeking advanced supply chain risk assessment solutions, which can ef ...

This project develops new methods for fabricating replicas of museum artifacts and other 3D objects that describe themselves when touched, so that museums can create exhibits that are accessible to everyone, including visitors with visual impairments. Phase I demonstrated how ordinary capacitive touchscreens could be repurposed as sensors for determining locations of finger touches on 3D surfaces ...

The development of a healthy behaviors through active design tool supports the initiatives focused on nutritionphysical activityand obesity by utilizing an evidence based web application to offer design solutions that influences healthy choicesThis feasibility study provides a prototype and establishes the commercial merit of the resulting research based applicationproviding health and wellness fe ...

The problems this contract is addressing include making it easy for patients to report toxicities after radiation therapy so that they can be timely and accurate and so that they can be incorporated into a medical database for use by medical professionals. This would allow the app to recommend (when appropriate), and for clinicians to intervene, with appropriate treatments and will lead to better ...

New therapies, designed to enhance anti-tumor immunity are based on the blockade of the checkpoint components, either PD-1 on immune cells or PD-L1 on tumor cells. This strategy, while being spectacularly successful in some patients for some cancers, fails for many other patients. The expression of PD-L1 is highly dynamic and its prevalence within tumors can vary significantly over time. The curre ...

Prostate cancer health disparities studies have shown that African-American (AA) men are at higher risk for developing prostate cancer, as well as at higher risk of cancer specific death rates, as compared to Caucasian American (CA) men. Causes of disparities have been attributed to socioeconomic differences, environmental exposures and biological factors; however, the lack of relevant in vitro an ...

Our company has invented a magnetic drug delivery device that we intend to develop to enable prevention of a major side effect of chemotherapy in children. Cisplatin and carboplatin chemotherapy regimens can lead to severe hearing loss, especially in pediatric patients. For cisplatin, hearing loss is FDA listed on-label as a dose limiting toxicity. Hearing loss in kids has a dramatic impact on the ...

Persistent cognitive impairment is a frequent complaint of cancer patients undergoing chemotherapy. The current tests used to assess cognitive function are not sensitive enough to capture the degree of decline associated with cancer-related cognitive impairment (CRCI). In addition, they require professional administration and are subject to practice effects so they cannot practically be used for t ...

This research project seeks to create innovative software that aids cancer patient caregivers,by improving their ability to access patient information, communicate with clinicians, and provide peer support. We seek to leverage the insights of stakeholders and subject matter experts as well as industry standards to enhance a caregiver facing SmartPhone app and related software developed in Phase I ...