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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Radiation-defect mitigation in InAs/GaSb strained-layer superlattice infrared detectors

    SBC: TRUVENTIC LLC            Topic: MDA16011

    This Phase II SBIR project will advance the technical readiness level (TRL) of our Phase-I-demonstrated strategy for mitigating radiation damage in GaSb/InAs Type II Strained-Layer-Superlattice (SLS) long-wave infrared (LWIR) detectors. Our mitigation strategy will be optimized for detectors to be deployed in interceptor seeker systems that will be exposed to radiation in the near-Earth orbital en ...

    SBIR Phase II 2018 Department of DefenseMissile Defense Agency
  2. Prototyping of Transform-Domain INS Mechanization and Algorithmic Correction

    SBC: QUNAV LLC            Topic: MDA16012

    QuNav proposes to validate and prototype a TRansform-domain INS Mechanization and Algorithmic Correction (TRIMAC). TRIMAC utilizes joint time/frequency domain processing of inertial sensor data in order to mitigate INS drift in the absence of external navaids (such as GPS). Frequency-domain implementation is particularly designed to improve the inertial performance in high-vibration missile enviro ...

    SBIR Phase II 2018 Department of DefenseMissile Defense Agency
  3. Risk Reduction Toolkit for Non Prescription Syringe Sales in Community Pharmacies

    SBC: HDOX BIOINFORMATICS INC            Topic: ODCDC

    A web based pharmacist training programand a patient centric decision support systemDSSfor pharmacies to implement risk reduction services for persons who inject drugsPWIDThe software will be interoperable with pharmacy and EHR systemsand generate tailored harm reduction counseling for PWIDA patient centric approach to decision support has the potential of improving the level of detail and accurac ...

    SBIR Phase I 2018 Department of Health and Human ServicesCenters for Disease Control and Prevention
  4. Topic 377: Symptom Management and Intervention Roadmaps (STaIRS)

    SBC: CAREVIVE SYSTEMS INC            Topic: NCI

    Numerous adverse symptoms are under-detected in cancer care resulting1-3 in missed opportunities for intervention; leading to poor treatment adherence, avoidable hospitalizations, and worse morbidity and survival. The IOM proposed shaking up the current symptom paradigm from reactive to proactive, personalized, technology-enabled models of symptom care as a solution to this clinical quality crisis ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  5. Topic 375: 18F PET Tracer For Imaging PD-L1 (Moonshot)

    SBC: SIBTECH, INC.            Topic: NCI

    New therapies, designed to enhance anti-tumor immunity are based on the blockade of the checkpoint components, either PD-1 on immune cells or PD-L1 on tumor cells. This strategy, while being spectacularly successful in some patients for some cancers, fails for many other patients. The expression of PD-L1 is highly dynamic and its prevalence within tumors can vary significantly over time. The curre ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  6. A Method to Increase Buprenorphine Treatment Capacity and Effectiveness

    SBC: CBT4CBT LLC            Topic: R42

    The goal of this fast track STTR proposal is to expand buprenorphine maintenance therapy for opioiddependent patientsOvermillion people in the US are addicted to opiatesProviding effective agonist therapymethadone or buprenorphinecoupled with behavioral counseling greatly improves outcomesreduces morbidityand reduces societal costsMethadone maintenance treatment has been limited due to complex sta ...

    STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  7. Development of an Oral Acidic Mammalian Chitinase Inhibitor to Treat Asthma

    SBC: ONCOARENDI THERAPEUTICS LLC            Topic: NHLBI

    Approximatelymillion Americans suffer from asthmawhich leads to aboutdeaths per yearand is responsible for estimated annual total direct and indirect costs of $billionDespite the existing treatments for asthmapredominantly combinations of inhaledagonists and corticosteroidsCSsthere remains a significant unmet medical need for new therapies which address two key issuesapproximatelyof patients are i ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  8. An antigen-detection assay to diagnose Babesia microti infection

    SBC: L2 DIAGNOSTICS LLC            Topic: NIAID

    Project Summary Human babesiosis is a malaria like multisystem disease caused primarily by Babesia microtian emerging apicomplexan parasite that infects and develops within human erythrocytesThe parasite is transmitted to humans by the tick vector Ixodes scapularis and can also be introduced through blood transfusionInfection can cause flu like symptomsand severe infection can be fatalin particula ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  9. TFEB Activator for Alzheimer's Disease Therapy

    SBC: BRILLIANT BIOSCIENCES INC.            Topic: NIA

    One in ten of the persons ageare affected by Alzheimer s diseaseADcausing enormous social and economic burden to the United StatesTo date only five medications have been approved by the FDA for the treatment of the symptoms of ADbut none of them slows or stops the disease progressionWith the recent repeated failures of AD drugs on thesecretase inhibitorsthe need for an effective AD drug became eve ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  10. Cpf1-mediated inactivation of an AAV transgene

    SBC: EMMUNE INC            Topic: NIAID

    PROJECT SUMMARY The Farzan laboratory has developed what appears to be an effective way to prevent HIVinfectionThis approach combines eCDIgan exceptionally broad and potent HIVentry inhibitorwith an adenoassociated virusAAVdelivery systemFor more than a year after a one time intramuscular inoculation with AAV eCDIgrhesus macaques were protected against multiple high dose intravenous challenges wit ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
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