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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. SBIR Phase II: An Interactive Graphical Application for Next-Generation Surveillance of Hospital-Acquired Infections using Whole Genome Sequencing and Advanced Analytics

    SBC: BIOINFOEXPERTS LLC            Topic: BT

    The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase II project will be a user-friendly and scalable infection control surveillance software platform using advanced biotech and data analytics for monitoring hospital-acquired infection. There is a significant clinical problem in hospitals, where 1 in 25 people who check in will develop a hospital acquired ...

    SBIR Phase II 2018 National Science Foundation
  2. 4-Demethyl-4-cholesteryloxycarbonylpenclomedine (DM-CHOC-PEN: A Phase II Clinical Trial in Adolescents/Young Adults (AYA)with CNS Malignancies

    SBC: DEKK-TEC INC            Topic: 102

    AbstractThe goal of this Phase II clinical trial application will be to evaluatedemethylcholesteryloxycarbonylpenclomedineDM CHOC PENas anticancer therapy for adolescents and young adultsAYAwith cancer involving the brain in a Phase II clinical trialDM CHOC PENFigis a polychlorinated pyridine cholesteryl carbonateFigthat is lipophilicelectrically neuralis able to cross the blood brain barrierBBBlo ...

    SBIR Phase II 2018 Department of Health and Human Services
  3. Development of a Hybrid Fixed Film- Biofloc System for Simplified Inland Production of Shrimp

    SBC: AQUACULTURE SYSTEMS TECHNOLOGIES, L.L.C.            Topic: 87

    The project goal is to integrate a fixed-film bioclarifier with suspended growth "biofloc" technology to increase production capacity and improve reliability for small Midwest farmers producing marine shrimp (Litopenaeus vannamei) in tanks. Research will focus on the determination of nitrification kinetics associated with an external aerated sludge basin, the confirmation of the maximum shrimp den ...

    SBIR Phase II 2018 Department of Agriculture
  4. Dynamic and Efficient Vapor Compressor

    SBC: BASCOM HUNTER TECHNOLOGIES, INC.            Topic: AF171057

    This Air Force SBIR project will develop and demonstrate a refrigerant vapor compressor that can provide up to 150 kW nominal cooling capacity.The developed compressor will be dynamically responsive to the needs of the vapor cycle system and can sustain high efficiency while providing cooling over the entire range of operating conditions for next generation aircraft.

    SBIR Phase II 2018 Department of DefenseAir Force
  5. Dynamic and Efficient Vapor Compressor for Aircraft Thermal Management Systems (TMSs)

    SBC: S-Ram Dynamics, LLC            Topic: AF171057

    S-RAM Dynamics (S-RAM) will design, fabricate, test, and commercialize a high-performance axial piston transcritical CO2 energy recovery compressor (ERC) to support next-generation aircraft thermal management systems for the U.S. Air Force and commercial applications

    SBIR Phase II 2018 Department of DefenseAir Force
  6. Evaluation of oral oleocanthal to prevent and/or treat Alzheimer's disease and related dementias

    SBC: Oleolive, LLC            Topic: NIA

    PROJECT SUMMARY Alzheimer s diseaseADis a progressive neurodegenerative disorder of the elderly that afflicts aboutmillion patients globally and overmillion Americans in the USDespite the considerable research effort to preventtreator cure the diseaseeffective strategies remain lackingThe accumulation of amyloidAin the brain blood vessels can result in the development of cerebral amyloid angiopath ...

    SBIR Phase I 2018 Department of Health and Human Services
  7. IND-Enabling Studies of ZB716, an Orally Bioavailable SERD

    SBC: Zenopharm, LLC            Topic: 102

    Project Summary Fulvestrant is the only FDA approved selective estrogen receptor downregulatorSERDindicated for advanced metastatic breast cancer that has progressed after or during tamoxifen or aromatase inhibitorAItreatmentIn July and Augustfulvestrant was approved as a first line endocrine agent for breast cancer patients by the European Medicines AgencyEMAand US FDArespectivelyHoweverthe drug ...

    SBIR Phase II 2018 Department of Health and Human Services
  8. SBIR Phase II: Smart Two-Way Shape Memory Polymer Based Sealant

    SBC: Louisiana Multi-functional-Materials Group LLC            Topic: MI

    This Small Business Innovation Research Phase II project aims to provide an affordable sealant for sealing joints and cracks in cement concrete pavement, asphalt concrete pavement, bridge deck, etc. In transportation infrastructure, joints are intentionally constructed in order to allow movement of the structural elements due to linear thermal expansion/contraction when temperature rises/drops. Cr ...

    SBIR Phase II 2018 National Science Foundation
  9. SBIR Phase I: High-Energy X-ray Gratings for Nondestructive Evaluation

    SBC: Refined Imaging, LLC            Topic: MN

    The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is the development of advanced X-ray imaging, high-energy X-ray grating-based interferometry, systems for nondestructive evaluation of additive manufacturing components. The image quality of the high-energy, X-ray grating-based interferometry imaging system will be advantageous for detecting c ...

    SBIR Phase I 2019 National Science Foundation
  10. STTR Phase I: Self-powered underwater light system for photosynthetic cultures

    SBC: Envirotronics, LLC            Topic: CT

    The broader impact/commercial potential of this project is to transform the culture of photosynthetic aquatic microorganisms. Although microalgae and cyanobacteria have high volumetric productivities, the cultures cannot be too deep, due to restrictions of light penetration. This proposed technology removes the light penetration limit inherent in current technologies. The results of this project w ...

    STTR Phase I 2019 National Science Foundation

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