Award Data

Historically, the combat medic has had one of the most important yet life-threatening roles on the battlefield. They must find, assess, treat and extract fellow injured soldiers in extremely hazardous conditions, sometimes with little or no additional support. Because of this, medics and other first responders are often injured or even killed while attending to wounded soldiers. To properly addres ...

Highly scalable parallel random number generators (RNGs) will be developed, evaluated and implemented for use in high performance computing on thousands of multi-core processors and general purpose graphics processing units. The main contributions are: (a) design and implementation of new parallel test methods that capture the inter-stream correlations exhibited in practice and complement the curr ...

NP Photonics proposes to develop a fiber-based, compact, tunable, THz spectroscopic/fingerprinting system that offers ultra-high resolution (< 1 MHz), high sensitivity and room temperature operation over the 1-3 THz range. This proposed system will provide high resolution molecular fingerprint information by leveraging NP Photonics high power and narrow linewidth fiber-based THz source, which is b ...

MESH, Inc. has developed a method to take data from multiple fixed site standoff sensors and generate concentration maps using either triangulation or tomography. The programs that MESH has developed will be modified to allow standoff from moving platforms to be used in the data merging process. A simulation suite of tools, also developed by MESH, will be used to set the requirements on the accu ...

This STTR project seeks to develop a new manufacturing system for large-scale, low-cost production of bulk ultrafine grained (UFG) or nanostructured metals in plate, sheet or bar forms. These capabilities will be based on scale-up of a new class of machining-based processes called large strain extrusion machining (LSEM) that has been effective at creating high strength, nanoscale microstructures i ...

DESCRIPTION (provided by applicant): The Kaposi's sarcoma-associated herpesvirus (KSHV) is the causative agent of cancers arising preferentially within immune compromised hosts, including patients infected with HIV. One of these cancers, a clonal B-cell malignancy known as primary effusion lymphoma (PEL), is associated with significant mortality, and there are currently no effective therapies for ...

DESCRIPTION (provided by applicant): Umbilical cord (UC) tissue has been established as a reliable source of stem cells for successful hematopoietic stem cell transplantations (HSCT). More than 5000 allogeneic cord blood (UCB) transplantations have been reported to treat both adults and children with hematologic diseases (1-5). Success can be attributed to several advantages including 1) accessibi ...

DESCRIPTION (provided by applicant): Otitis media is a general term for middle-ear inflammation that is classified clinically as either acute otitis media (AOM) or otitis media with effusion (OME). AOM represents a bacterial super infection of the middle ear fluid and OME a sterile effusion that tends to subside spontaneously. Antibiotics are generally beneficial only for AOM. Accurate diagnos ...

DESCRIPTION (provided by applicant): Optimal use of operating room (OR) personnel and resources is an important problem from multiple perspectives. Unanticipated waits and delays continue to add tremendous costs and negatively impact outcomes. There are over 55 million ambulatory and 45 million inpatient procedures performed in the U.S. annually, with increasing case complexities and patient comor ...

DESCRIPTION (provided by applicant): Nanosystems have been extensively investigated for drug delivery; however, there is a challenge in transferring nanotechnology from research laboratories into pharmaceutical industry. The scientific basis for this proposal originated from our three-phase nanoparticle engineering (3PNE) method recently developed which includes phase 1, amorphous precipitate; p ...