Award Data

Highly scalable parallel random number generators (RNGs) will be developed, evaluated and implemented for use in high performance computing on thousands of multi-core processors and general purpose graphics processing units. The main contributions are: (a) design and implementation of new parallel test methods that capture the inter-stream correlations exhibited in practice and complement the curr ...

The goal of this Phase I proposal is to develop a synthetic, low cost, and benign simulant for biowarfare agents (BWA) to be used in the testing of standoff sensors. Orono Spectral Solutions Inc. (OSS) has performed preliminary work leading to the identification of benign ingredients that, when combined in a predefined mass ratio, mimic UV-Vis and infrared signatures of BG spores. This work was pe ...

The overall goal of this Phase I project is to demonstrate the feasibility of an infrared transparent, micro-fluidic sampling system that will lead to a field-deployable detection system capable of detecting low ppb levels of chemical warfare (CW) agents in water. To accomplish this goal, the proposed detection system will combine high surface area, organically modified mesoporous oxide absorptiv ...

A rapid assay for the detection of T2 trichothecene mycotoxin in water is proposed that will use ANP Technology, Inc.'s established handheld reader and rapid acetylcholinesterase (AChE) inhibitor test ticket format. Dipain-II and other candidate Dipain derivatives will be immobilized on cellulose and other solid supports mounted as discs in wells on the existing test ticket, similar to the AChE i ...

DESCRIPTION (provided by applicant): Advanced Medical Electronics Corp, in collaboration with the Johns Hopkins University School of Medicine, proposes to develop a hardware/software platform suitable for administering a variety of tests and survey instruments to underserved populations in settings that can range from living rooms to libraries, community centers to nursing homes, and from inner ci ...

DESCRIPTION (provided by applicant): This STTR application is to develop and test for eventual clinical use a new strategy for tumor specific anticancer drug delivery. The technology, Clostridia-directed enzyme prodrug therapy, or CDEPT, exploits the fact that certain non-pathogenic bacteria of the Clostridia genus, which only grow in the absence of oxygen (hypoxia), colonize the hypoxic and necr ...

DESCRIPTION (provided by applicant): It is uniformly recognized that sedentariness - the sitting disease - is bad for the health of the nation. The solution to reversing sedentariness involves devising and disseminating real-world solutions to promote day-long physical activity and help people who want to, to lose weight and improve their blood glucose, lipids and blood pressure. The Gruve is ...