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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Highly efficient, compact, picosecond green laser for time resolved fluorescence

    SBC: ADVR, INC.            Topic: NCRR

    DESCRIPTION (provided by applicant): The primary goal of the Phase I effort is to establish the feasibility of fabricating waveguides to realize a significant, (10 fold), increase in performance in the output power of a picosecond pulsed green laser without increasing the peak pump power. The ultimate goal is to develop a fiber pigtailed, compact, cost-effective 530 nm picosecond laser producing 1 ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  2. A NEW BIOSENSOR BASED ON CATASTROPHIC PROTEIN CHANGES

    SBC: ATERIS Technologies            Topic: NIEHS

    DESCRIPTION (provided by applicant): This Phase I project will test the idea that mechanostress-sensitive, fluorescent polymers can detect structural changes induced in proteins following reaction of the protein with small molecule inhibitors. This concept will be tested and proven using recombinant acetylcholinesterase (AChE) an enzyme that is known to undergo catastrophic denaturation when it re ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  3. TARGETED TWO-PHOTON PHOTODYNAMIC THERAPY TRIADS

    SBC: SENSOPATH TECHNOLOGIES, INC.            Topic: NCI

    The objectives are to further the pre-clinical development of unique two-photon activated Photodynamic Therapy (PTD) triads that incorporate a photosensitizer, a tumor receptor targeting group, and an imaging functionality, providing a noninvasive treatment of recurrent and refractory Head and Neck (HandN) tumors deep below the skin surface, in an outpatient setting.

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  4. Development of a selective biosensor for detecting organophosphate pesticide expo

    SBC: ATERIS Technologies            Topic: N/A

    DESCRIPTION (provided by applicant) This SBIR project is in response to the call for the development of field-deployable or wearable personal sensors for monitoring point-of-contact exposures to airborne chemicals through biosample testing. The broad objective of this proposal is to develop an extremely sensitive and selective biosensor device capable of detecting and discriminating protein ...

    SBIR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  5. Composite Supports for High Throughput Chromatography

    SBC: CHELATECH, INC.            Topic: N/A

    N/A

    SBIR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  6. Composite Supports for High Throughput Chromatography

    SBC: CHELATECH, INC.            Topic: N/A

    N/A

    SBIR Phase II 2001 Department of Health and Human ServicesNational Institutes of Health
  7. COMPOSITE SUPPORTS FOR RAPID POLYNUCLEOTIDE SYNTHESIS

    SBC: CHELATECH, INC.            Topic: N/A

    DESCRIPTION (applicant's abstract): Modern DNA synthesis methods make use of porous solid phase supports that are used to immobilize the first base in the sequence. This process is inherently inefficient, because solutes and solvent flowing through a column of porous media prefer the path of least resistance. Flow naturally goes around the particles, rather than throug ...

    SBIR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  8. New Experimental and Computational Tools for Tissue Engineering

    SBC: Fluorescence Innovations, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Tissue engineering aims to create functional biologic prostheses by suspending dissociated cells into a biodegradable polymer scaffold upon which new tissue forms. Better means are urgently needed to compare engineered tissues, particularly cartilage and other soft tissues, with normal tissue. Histology is slow, cumbersome, and destructive because it requires f ...

    SBIR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  9. Software Relating Genes to Disease and Clinical Outcomes

    SBC: Golden Helix, Inc.            Topic: N/A

    DESCRIPTION (Applicant's abstract): The development of a software system is proposed that will combine statistical theory, computer science algorithms, and genetics expertise to take advantage of the great influx of data generated by both the study of the human genome and the creation of inexpensive genotyping techniques. This software will elucidate the complex relatio ...

    SBIR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  10. Software Relating Genes to Disease and Clinical Outcomes

    SBC: Golden Helix, Inc.            Topic: N/A

    Not Available DESCRIPTION (provided by applicant): The development of a software system is proposed that will combine statistical theory, computer science algorithms, and genetics expertise to take advantage of the great influx of data generated by the study of the human genome, clinical trials data and the creation of inexpensive genotyping techniques. This software will elucidate the complex re ...

    SBIR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health
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