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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Highly efficient, compact, picosecond green laser for time resolved fluorescence
SBC: ADVR, INC. Topic: NCRRDESCRIPTION (provided by applicant): The primary goal of the Phase I effort is to establish the feasibility of fabricating waveguides to realize a significant, (10 fold), increase in performance in the output power of a picosecond pulsed green laser without increasing the peak pump power. The ultimate goal is to develop a fiber pigtailed, compact, cost-effective 530 nm picosecond laser producing 1 ...
SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health -
Not Available
SBC: BioSavita, Inc. Topic: NCIApoLife is developing yeast platform-Twin Cassette yeast vectors for cost effective manufacturing of antibodies. Using recent collaboration with a company with proprietary S. cerevisiae yeast strains producing homogeneous human N-linked glycosylated proteins, ApoLife will develop commercial scale process for cost effective manufacturing of Campth, anticancer antibody, as a biogeneric antibody cand ...
SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health -
A NEW BIOSENSOR BASED ON CATASTROPHIC PROTEIN CHANGES
SBC: ATERIS Technologies Topic: NIEHSDESCRIPTION (provided by applicant): This Phase I project will test the idea that mechanostress-sensitive, fluorescent polymers can detect structural changes induced in proteins following reaction of the protein with small molecule inhibitors. This concept will be tested and proven using recombinant acetylcholinesterase (AChE) an enzyme that is known to undergo catastrophic denaturation when it re ...
SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health -
Custom Oligonucleotide Libraries synthesis
SBC: BIODISCOVERY LLC Topic: NIGMSDESCRIPTION (provided by applicant): There is a growing demand for custom synthesis of short genes libraries coding for active peptides or regulatory RNAs. DNA microarrays can be manufactured by synthesizing oligonucleotides on solid substrate in a massively-parallel manner using a high-yield low cost chemistry. Oligonucleotides can be cleaved off the microarray surface and recovered as a pool ...
SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health -
Low cost, high density custom peptide microarray synthesis205
SBC: BIODISCOVERY LLC Topic: NIGMSDESCRIPTION (provided by applicant): Peptides play a significant role in the defense mechanisms of the body and binding of cells, bacteria and viruses to surfaces. Combinatorial peptide chemistry has emerged as a powerful tool for mapping receptor-ligand interactions in drug discovery applications as well as epitope mapping. There is a huge, but largely unrealized, potential for peptide microarray ...
SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health -
Three-dimensional visualization, interactive analysis and contextual mapping of s
SBC: BIO-ANALYTICS, INC. Topic: NCIDESCRIPTION (provided by applicant): This project is developing the first software to offer 3D visualization of health outcomes in a combined time and geography space, allowing the display of health data at multiple spatial and temporal scales within the same scene and thus taking full advantage of human visual perception that is fundamentally three dimensional. This visualization analytics enviro ...
SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health -
ADVANCED MICROFABRICATION TECHNOLOGY
SBC: CLARK-MXR, INC. Topic: NIDCDDESCRIPTION (provided by applicant): The broad, long-term objective of this program is to develop the tools, protocols and facilities needed to produce multielectrode arrays (MEAs) out of known biocompatible materials for eventual use in humans. This will require construction and commissioning of a computer-aided design (CAD), good manufacturing practice (GMP) facility and framework capable of fab ...
SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health -
Incorporating microRNA data and analyses into the leading cancer genomics portal
SBC: COMPENDIA BIOSCIENCE, INC. Topic: NCIDESCRIPTION (provided by applicant): Micro-RNAs (miRNAs) are small non-coding RNAs that control gene expression by regulating messenger (mRNA) translation. miRNAs can act as oncogenes or tumor suppressors, and the differential expression of miRNAs has been correlated with cancer diagnosis, staging, and prognosis, and has been used to nominate therapeutic targets. Much of what is known about miRNAs ...
SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health -
Not Available
SBC: DETROIT R & D, INC. Topic: NIEHSNot Available
SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health -
Software for the accurate de novo 3D structure prediction of RNA
SBC: DNA SOFTWARE, INC. Topic: NIGMSDESCRIPTION (provided by applicant): The discovery of new and interesting RNA sequences from genome sequencing projects, and the urgency to unravel their functions, has led to a dramatic push for novel structural determination techniques. Current experimental methods for three dimensional structure determination of nucleic acids such as x-ray crystallography and NMR cannot keep pace with the day t ...
SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health