Award Data

IN 1985, 900,513 POISONINGS--328 FATALITIES--WERE REPORTED TO THE AMERICAN ASSOCIATION OF POISON CONTROL CENTERS. SIXTY-FOUR PERCENT INVOLVED CHILDREN UNDER AGE SIX. SEVENTEEN PERCENT OF 2,015 PRESCRIPTION DRUG INGESTIONS INVOLVED GRANDPARENTS' DRUGS. RECENT STUDIES HAVE CONFIRMED THAT MANY ELDERLY HAVE TROUBLE OPENING CHILD-PROOFCONTAINERS. THE OBJECTIVE OF THIS RESEARCH IS TO ESTABLISH THE TECHN ...

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This proposal addresses the need to develop products which will help participants in health care assquality and level of care furnished to patients. We will develop a prototype ¿Protocol Engine¿, withdesigned for personal computers and computer networks, to allow protocols to be defined and customizspecific needs of the organization; to link and/or access data from other medical software package ...

Many lung disorder patients (cystic fibrosis, COPD) require supplemental oxygen. Studies showboth quality and length of life improves if these patients maintain active mobile lives. Their mobility islimited, since many need to stay near their supplemental oxygen source. Portable oxygen enriching air(OEA) membrane systems could provide the needed portability to improve these patients' lives. We wil ...

Dengue virus causes dengue fever, a debilitating illness marked by high fever, headache, muscleand joint pain, and rash. The more severe forms of the illness, dengue hemorrhagic fever and dengueshock syndrome, are life threatening and are a principal cause of hospitalization among children inSoutheast Asia. Globally, the four serotypes of dengue are responsible for up to 100 million infectionsannu ...

The neurotoxins of Clostridium botulinum are the most lethal proteins known. The bacterium is ubiquitous, and thus rapid, reliable, sensitive, and cost-effective assays are needed to detect the toxin. Current immunoassays provide a rapid means to detect the neurotoxin. Their sensitivity, however, is limited by the affinity of the detecting antibody. The objective of this research, therefore, i ...

Ultra-high-purity silica microspheres recently were introduced primarily for analytical high-performance liquid chromatography (HPLC). However, these materials are expensive and are available only in limited configurations. The aim is to explore new methods for preparing strong, ultra-high-purity silica microspheres (or microspheroids) of lower cost in a variety of configurations (particle size, p ...

The information produced by the Human Genome Project and related research is expected torevolutionize biology and medicine in general and recombinant DNA technology in particular. At present,however, obtaining patent protection for inventions involving recombinant DNA technology is anacknowledged bottleneck in the development of the U.S. biotechnology industry. While much attentionhas been focused ...