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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. " Channel Multimodal Ultrathin Flexible SFE for cancer diagnosis and therapy"

    SBC: VERAVANTI INC.            Topic: 102

    Summary channel multimodal ultrathin flexible SFE for cancer diagnosis and therapy Minimally invasive optical imaging is being advanced by molecular probes that enhance contrast using fluorescence The applications in cancer imaging are very broad ranging from early diagnosis of cancer to the guiding of interventions such as surgery The high sensitivity afforded by wide field fluorescence i ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  2. "Grid-Tape": A High-Throughput Platform for Brain Connectomics and Nanoscale Structural Analysis

    SBC: Luxel Corporation            Topic: 101

    The wiring diagram of brain circuits is one of the foundational and fundamental questions of modern neuroscienceExtracting a circuit sized volume at synaptic resolution requires large scalehigh throughput imaging of many thin sections of brain tissueThe immediate goal of researchers is to capture and map a cubic millimeter of cortex at synaptic resolutionrequiring the collection and imaging oftiss ...

    SBIR Phase I 2017 Department of Health and Human Services
  3. A Collaborative Interface for Teacher-Student Interaction in Virtual Environments

    SBC: STRANGE LOOP GAMES INC.            Topic: edIES17R0005

    In prior projects, including a 2015 ED/IES SBIR award, the team developed two immersive multiplayer virtual game environments. In Eco and Colony, middle school students collaboratively apply scientific practices within the virtual worlds to address challenges, such as the availability of resources and energy and maintaining clean water. With this Phase I funding, the team is developing a prototype ...

    SBIR Phase I 2017 Department of EducationInstitute of Education Sciences
  4. A high throughput sample preparation platform for genomic and epigenetic analysis

    SBC: Matchstick Technologies Inc.            Topic: 200

    Several types of cancers e g pancreatic and brain malignancies remain extremely lethal despite the introduction of chemotherapy more than years ago The hallmark of all cancers are somatic mutations which cannot be corrected In sharp contrast epigenetic changes essential contributors to tumorigenesis are pharmacologically reversible The ability to remedy detrimental epigenetic alteratio ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. A high-throughput sample preparation platform for genomic and epigenetic analysis

    SBC: Matchstick Technologies Inc.            Topic: 400

    Several types of cancerse gpancreatic and brain malignanciesremain extremely lethal despite the introduction of chemotherapy more thanyears agoThe hallmark of all cancers are somatic mutations which cannot be correctedIn sharp contrastepigenetic changesessential contributors to tumorigenesisare pharmacologically reversibleThe ability to remedy detrimental epigenetic alterations are opening up new ...

    SBIR Phase II 2017 Department of Health and Human Services
  6. A Novel Peptide Therapeutic for Obesity

    SBC: VIRTICI LLC            Topic: 300

    Project Summary The goal of this project is to develop a novel peptide therapeuticVTC Gfor the treatment of obesityTodayone third of adults in the United StatesUSare obesewith an estimated annual healthcare burden of approximately $billionByit is projected that overof adults in the US will be obese with a yearly healthcare burden expected to exceed $billionwhich will account for approximatelyof th ...

    SBIR Phase II 2017 Department of Health and Human Services
  7. A Novel Probiotic for the Treatment of Rheumatoid Arthritis

    SBC: VIRTICI LLC            Topic: NIAMS

    Project Summary Our goal is to develop a novel L lactis probiotic based therapeutic for the treatment of rheumatoid arthritis RA RA is a chronic systemic inflammatory disorder affecting as much as worldwide and as much as of the US population The exact frequencies depend on geographical origin and gender women being three times more affected than men While many organs are affecte ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. A Novel Tolerance inducing Probiotic Platform

    SBC: VIRTICI LLC            Topic: NIAID

    Project Summary Our goal is to validate a novel Lactococcus lactis L lactis based platform to rapidly develop and deliver tolerance inducing therapeutics for the treatment of autoimmunity and allergy Autoimmune and allergic diseases such as Multiple Sclerosis MS Type Diabetes and food allergies affect of the world population and are continuing to rise These illnesses are the ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. A Novel Tolerance Therapeutic for Treating Multiple Sclerosis

    SBC: VIRTICI LLC            Topic: NIAID

    Our goal is to develop VTC MSas a novel tolerance inducing therapeutic to treat Multiple SclerosisMSMS is the most common demyelinating disorder of the Central Nervous SystemCNSaffecting approximatelymillion people worldwide andin the US aloneCurrent and developing treatment of MS relies mainly on immuno suppression and modulation to reduce inflammatory symptoms creating a significant need for new ...

    SBIR Phase II 2017 Department of Health and Human Services
  10. A Novel Tolerance Therapeutic for Treating Type Diabetes

    SBC: VIRTICI LLC            Topic: 200

    Project Summary Our goal is to develop VTC D as a novel tolerance inducing therapeutic for the treatment of Type Diabetes T D T D is an autoimmune disease characterized by the destruction of the insulin producing pancreatic beta cells While the etiology of T D remains undefined evidence suggests that autoimmunity to insulin is a major driver of disease initiation Each year over ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health

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