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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Correlating TCR diversity to immune reconstitution after cord blood transplant

    SBC: ADAPTIVE BIOTECHNOLOGIES CORPORATION            Topic: NHLBI

    DESCRIPTION provided by applicant Many patients requiring stem cell transplantation for hematological malignancies are unable to find a suitable HLA matched sibling or unrelated donor Transplants using stem cells from umbilical cord blood provide an alternative for these patients allowing transplantation to proceed with less stringent HLA matching requirements Unfortunately in addition to t ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Aerosol Sampling and Microfluidic Analysis of Reactive Oxygen Species

    SBC: ILLIONIX, LLC            Topic: 113

    DESCRIPTIONprovided by applicantCardiovascular diseases and Asthma affects betweenandmillion people in the United States includingmillion childrenduring the pastyearsits incidence worldwide has doubledAsthma is responsible formillion person days of restricted activity anddeaths per yearamounting to $billion in direct heath related coststhere is uncertainty about the specific factors that are contr ...

    STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Using Mobile Technology to Enhance MST Outcomes

    SBC: EVIDENCE-BASED PRACTICE INSTITUTE, INC.            Topic: 104

    PROJECT SUMMARY ABSTRACTEach yearover one million adolescents are arrestedmany more engage in other serious conduct problemsincluding binge drinkingillicit drug useand school drop outCollectivelythese problems result in enormous costs to individualsfamiliesand societyThe most effective interventions to address these problems are family basedwith a strong clinical emphasis on helping parents better ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Self-Digitization Microfluidic Platform for Digital PCR

    SBC: LAMPROGEN INC            Topic: 400

    Project Summary AbstractThis SBIR Direct Phase II project will produce a complete platform to perform nucleic acid quantificationNAQby digital polymerase chain reactiondPCRThe platform will consist of a complete instrument that handles devices and executes all phases of the assaydigitizationamplificationand detectionin one instrumentoffering truewalk awaycapabilities within a closed systemIt will ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Mouse Stem Cell Research Using the Dracula Pipette

    SBC: GENESEARCH, INC.            Topic: 100

    Advanced approaches for genetic or epigenetic modification of embryonic stemEScellsincluding TALENZFNor CRISPR catalyzed genetic modifications or modulation of gene expression via small RNAssynthetic mRNAsor recombinant transcription factorshave revolutionized our ability to modify the cells from which novel mouse lines are producedIn contrastprocedures for utilizing these cells within the context ...

    STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Long non-coding RNA signatures to classify multiple sclerosis

    SBC: IQuity Labs, Inc.            Topic: NIAID

    Diagnosis of relapsing remitting multiple sclerosisMSrests on clinical symptoms and examinations asoutlined in the revised McDonald s criteria supported by appropriate magnetic resonance imaging findings andother laboratory testsThe need for early diagnosis is clearly emphasized in a position paper produced inby MS Brain Health organization calledBrain healthTime matters in multiple sclerosiswhich ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  7. A Novel Tolerance Therapeutic for Treating Multiple Sclerosis

    SBC: VIRTICI LLC            Topic: NIAID

    Our goal is to develop VTC MSas a novel tolerance inducing therapeutic to treat Multiple SclerosisMSMS is the most common demyelinating disorder of the Central Nervous SystemCNSaffecting approximatelymillion people worldwide andin the US aloneCurrent and developing treatment of MS relies mainly on immuno suppression and modulation to reduce inflammatory symptoms creating a significant need for new ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  8. A Novel Peptide Therapeutic for Obesity

    SBC: VIRTICI LLC            Topic: 300

    Project Summary The goal of this project is to develop a novel peptide therapeuticVTC Gfor the treatment of obesityTodayone third of adults in the United StatesUSare obesewith an estimated annual healthcare burden of approximately $billionByit is projected that overof adults in the US will be obese with a yearly healthcare burden expected to exceed $billionwhich will account for approximatelyof th ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Device for Otitis Media Diagnosis

    SBC: OtoNexus Medical Technologies, Inc.            Topic: Y

    OtoNexus is developing the world s first medical device to provide definitiveobjective diagnostic data for the rapid and accurate diagnose middle ear infectionscalled Otitis Mediain children and adultsThis FAST TRACK proposal addresses the clinical difficulty of determining the nature of fluid behind the tympanic membraneear drumin acute infection of the middle earAcute Otitis MediaAOMClinical stu ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  10. A Hand-Held Robot to Cure BPH

    SBC: VIRTUOSO SURGICAL, INC.            Topic: NIBIB

    Project Summary AbstractThe objective of this proposal is to transform a hand held surgical robotic system for transurethral laser prostate surgery from a lab prototype into a commercial productThe system will feature needle sized arms deployed through the endoscope port and will enable independent tissue manipulationlaser aimingand visualizationmaking surgery more accurate and ef cientClinical si ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
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