Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until September, 2020.

  1. Development of an Open Speech Signal Processing Platform

    SBC: Flat Earth, Inc.            Topic: NIDCD

    This proposal will create an open speech signal processing platformThe open computational framework will be used for developing algorithms that will help accelerate acoustic and hearing science researchIt will permit researchers to more rapidly and easily test new algorithms with greater controlperformanceand easeSeveral example systems will be created to show that the platform can be adapted to a ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Marketing Strategic Plan and Distribution Logistics for Sanaria PfSPZ Vaccine against Malaria.

    SBC: SANARIA INC.            Topic: NIAID

    ABSTRACT The development of Sanaria s Plasmodium falciparumPfsporozoiteSPZbased vaccines is receiving overwhelming global support after the publication inin Science of clinical data showingprotection against controlled human malaria infectionCHMIfollowing intravenous administration ofdoses of SanariaPfSPZ Vaccinecomposed of purifiedasepticradiation attenuatedcryopreserved PfSPZ meeting all regulat ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  3. AVGN7, a Novel Gene Therapeutic for Treating Cancer Cachexia

    SBC: Aavogen, Inc.            Topic: 102

    PROJECT SUMMARYThe skeletal muscle wasting that occurs with cancer cachexia compromises quality of life and is both directly and indirectly responsible for cancer mortalitiesTumor derived and tumor responsive factors as well as many therapeutics themselves contribute to the cachectic statealthough nutritional support has little if any positive effect on restoring striated muscle mass or functionTh ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Rapid Molecular Detection of Tuberculosis without PCR amplification

    SBC: SCANOGEN INC.            Topic: NIAID

    Project Summary TuberculosisTBis a major global burden that killsmillion people every yearTB mostly affects developing countriesbut the rise of multi drug and extensively drug resistant strains is a global threatIn order to control and eradicate this diseaseit is imperative to have adequate tools to detect active TB in limited resource settings and point of carePOCsettingswhich is where most TB pa ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Drug Delivery Method for Sudden Sensorineural Hearing Loss

    SBC: Weinberg Medical Physics, Inc.            Topic: NIDCD

    Project Summary Abstract The ultimate goal of the proposed project is to evaluate and commercialize a combination of proprietary magnet assemblies and magnetic nanoparticles that has been shown in small animal and cadaveric large animal and human studies to improve delivery of medications to the inner earStudies using the systemwhich uses magnetic forces to inject drug eluting magnetic nano partic ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Kinetic Phenotype Discovery Informatics for Neurological Diseases

    SBC: DRVISION TECHNOLOGIES LLC            Topic: 101

    Project Summary Neurological disorders significantly outnumber diseases in other therapeutic areas and are growing in incidence faster than any other disease classesHoweverthe pharmaceutical industry has been unsuccessful in coming up with effective drugsA big factor in these failures has been a lack of adequate model systems for fundamental disease understanding affecting both diagnosis and treat ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  7. A clinical process support system for primary care to address family stress

    SBC: Total Child Health, Inc.            Topic: NICHD

    This proposal addresses the NICHD focus of specific interest for the prevention of child abuse and neglect in at risk populationsChild abuse and neglect often confers shortand long term impairment of the physicalemotionaland cognitive development of childrenThe proposed project builds on promising data from previous randomized control trialsbased on application of a screening tool in primary care ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Enabling point-of-care molecular diagnostics by developing an adaptive PCR instrument and on-demand kit reagents

    SBC: BIOVENTURES, INC            Topic: 172

    Because of its high sensitivitypolymerase chain reactionPCRis the gold standard for the diagnosis of many infectious diseasesbut generally only implemented in well equipped laboratoriesOne of the major roadblocks for expanding PCR to point of care markets is the lack of simplerobustsingle tube PCR designs which preserve its laboratory based high sensitivity and specificityIn this Fast Track STTR a ...

    STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  9. A Hand-Held Robot to Cure BPH

    SBC: Virtuoso Surgical, Inc.            Topic: NIBIB

    Project Summary AbstractThe objective of this proposal is to transform a hand held surgical robotic system for transurethral laser prostate surgery from a lab prototype into a commercial productThe system will feature needle sized arms deployed through the endoscope port and will enable independent tissue manipulationlaser aimingand visualizationmaking surgery more accurate and ef cientClinical si ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Immune Deficient Mosquitoes for Improved Malaria Sporozoite Vaccine Manufacture

    SBC: SANARIA INC.            Topic: NIAID

    Abstract An ideal tool for eliminating Plasmodium falciparumPfthe causative agent ofof all malaria deathswould be a highly effective vaccine that prevents blood stage infection and thereby prevents both disease and transmissionSanaria has developed two effective vaccines that are phaseclinical trialsPf sporozoiteSPZvaccine that prevents Pf blood stage infection in andgtof recipients and PfSPZ Chal ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
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