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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Peripheral nerve stimulation for amputee pain

    SBC: SPR THERAPEUTICS, INC.            Topic: 105

    AbstractThe goal of the presently proposed Commercialization Readiness PilotCRPProgram project is to prepare for commercialization of an implantable systemdeveloped in Phase IIthat is capable of delivering a novel peripheral nerve stimulationPNStherapy shown to be highly effective in treating intractable pain in a majority of amputees in previous studiesincluding Phase IApproximatelymillion indivi ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Kinetic Phenotype Discovery Informatics for Neurological Diseases

    SBC: DRVISION TECHNOLOGIES LLC            Topic: 101

    Project Summary Neurological disorders significantly outnumber diseases in other therapeutic areas and are growing in incidence faster than any other disease classesHoweverthe pharmaceutical industry has been unsuccessful in coming up with effective drugsA big factor in these failures has been a lack of adequate model systems for fundamental disease understanding affecting both diagnosis and treat ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Enabling point-of-care molecular diagnostics by developing an adaptive PCR instrument and on-demand kit reagents

    SBC: BIOVENTURES, INC            Topic: 172

    Because of its high sensitivitypolymerase chain reactionPCRis the gold standard for the diagnosis of many infectious diseasesbut generally only implemented in well equipped laboratoriesOne of the major roadblocks for expanding PCR to point of care markets is the lack of simplerobustsingle tube PCR designs which preserve its laboratory based high sensitivity and specificityIn this Fast Track STTR a ...

    STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Commercialization of an MRI contrast agent for differential diagnosis ofprostate cancer.

    SBC: MOLECULAR THERANOSTICS, LLC            Topic: NCI

    Contact PD PILiYajuan AbstractParent GrantProstate cancer is a highly heterogeneous disease and the second most cause of cancer death of men in the USCurrent methods to assess prostate cancer risk combine prostate specific antigenPSAscreening and random prostate biopsyUnfortunatelythis strategy fails to reveal the lesion s location and does not accurately differentiate between aggressive and non a ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  5. A phase IIA trial for the safety and tolerability of CD24Fc in prophylaxis of graft vs host disease.

    SBC: Oncoimmune Inc            Topic: 102

    Project Summary AbstractAcute graft versus host diseaseaGVHDis a principal contributor to transplant related mortalityTRMand develops in approximatelyof recipients receiving unrelated donor hematopoietic stem cell transplantationHSCTdespite standard immunosuppressive prophylaxisThusnovel GVHD prophylaxis treatments which successfully attenuate aGVHD and related complications such as infection are ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Development of Chemistry, Manufacturing, and Control Standards for PGC and PGC-dANP

    SBC: PHARMAIN CORPORATION            Topic: NHLBI

    ABSTRACTThis application is seeking funding specifically for ChemistryManufacturingand ControlCMCof scale up production of long acting atrial natriuretic peptidedANPand its protected graft co polymerPGCexcipient for use in heart failureHFtreatmentThe extrinsic merit of this project will be the availability of cGMP grade PGC for use in prolonging the half life of various peptide drugs that are in p ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  7. A Novel Tolerance Therapeutic for Treating Multiple Sclerosis

    SBC: VIRTICI LLC            Topic: NIAID

    Our goal is to develop VTC MSas a novel tolerance inducing therapeutic to treat Multiple SclerosisMSMS is the most common demyelinating disorder of the Central Nervous SystemCNSaffecting approximatelymillion people worldwide andin the US aloneCurrent and developing treatment of MS relies mainly on immuno suppression and modulation to reduce inflammatory symptoms creating a significant need for new ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Development of an Open Speech Signal Processing Platform

    SBC: SensorLogic, Inc.            Topic: NIDCD

    This proposal will create an open speech signal processing platform. The open computational framework will be used for developing algorithms that will help accelerate acoustic and hearing science research. It will permit researchers to more rapidly and easily test new algorithms with greater control, performance, and ease. Several example systems will be created to show that the platform can be ad ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  9. A Novel Peptide Therapeutic for Obesity

    SBC: VIRTICI LLC            Topic: 300

    Project Summary The goal of this project is to develop a novel peptide therapeuticVTC Gfor the treatment of obesityTodayone third of adults in the United StatesUSare obesewith an estimated annual healthcare burden of approximately $billionByit is projected that overof adults in the US will be obese with a yearly healthcare burden expected to exceed $billionwhich will account for approximatelyof th ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Development of a Fully Humanized Antibody for Treating Lung Emphysema

    SBC: Allinaire Therapeutics, LLC            Topic: NHLBI

    Project Summary COPD is a common and serious disease with no cure that is characterized by chronicprogressive lung damagea decline in pulmonary function and quality of lifeand often deathThe two major clinical features of COPD are emphysema and chronic bronchitisCOPD is mainly associated with exposure to cigarette smokeCShoweveraboutof COPD patients have a genetic deficiency of alphaantitrypsinAAT ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
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