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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Real-Time Spliced-RNA Detection to Quantify Latent HIV-Infected Cells in HAART Patients

    SBC: Jan Biotech, Inc.            Topic: R

    PROJECT SUMMARY ABSTRACT Public Health Problem In the U Speople agedyears and older are living with HIV infectionwith approximatelyothers infected but undiagnosedFor most HIV positive individualsavailable treatments can only control HIV infection and delay progression to AIDSHAART has substantial side effects and fails to prevent at leastof patients from developing HIVassociated neurocognitive dis ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Kinetic Phenotype Discovery Informatics for Neurological Diseases

    SBC: DRVISION TECHNOLOGIES LLC            Topic: 101

    Project Summary Neurological disorders significantly outnumber diseases in other therapeutic areas and are growing in incidence faster than any other disease classesHoweverthe pharmaceutical industry has been unsuccessful in coming up with effective drugsA big factor in these failures has been a lack of adequate model systems for fundamental disease understanding affecting both diagnosis and treat ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Enabling point-of-care molecular diagnostics by developing an adaptive PCR instrument and on-demand kit reagents

    SBC: BIOVENTURES, INC            Topic: 172

    Because of its high sensitivitypolymerase chain reactionPCRis the gold standard for the diagnosis of many infectious diseasesbut generally only implemented in well equipped laboratoriesOne of the major roadblocks for expanding PCR to point of care markets is the lack of simplerobustsingle tube PCR designs which preserve its laboratory based high sensitivity and specificityIn this Fast Track STTR a ...

    STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Monitoring and Stabilizing Behavioral Rhythms to Improve Mental Health

    SBC: Health Rhythms, Inc.            Topic: 104

    AbstractHealthRhythmsIncSubstantial evidence supports the idea that disruptions in the regularity of behavioral routinesorsocial rhythmscan lead to the onset of psychiatric symptoms and full blown episodes via their impact on endogenous circadian rhythms andconversely that stable social routines protect against new mood episodesBased on our conviction that monitoringevaluatingand increasing the re ...

    SBIR Phase II 2017 Department of Health and Human Services
  5. Quantum Digital Technology for Wideband Signal Reception

    SBC: HYPRES, INC.            Topic: N092154

    HYPRES proposes to develop wideband analog-to-digital converters (ADCs) using ultrafast superconductor electronics integrated circuit (IC) technology. The objective is to build upon our prior work on superconductor ADCs to achieve higher sampling rate. In addition, we propose to pursue architectural innovations to obtain higher resolution than that which was achieved before at a given sampling rat ...

    SBIR Phase II 2017 Department of DefenseNavy
  6. Development of Chemistry, Manufacturing, and Control Standards for PGC and PGC-dANP

    SBC: PharmaIN Corporation            Topic: NHLBI

    ABSTRACTThis application is seeking funding specifically for ChemistryManufacturingand ControlCMCof scale up production of long acting atrial natriuretic peptidedANPand its protected graft co polymerPGCexcipient for use in heart failureHFtreatmentThe extrinsic merit of this project will be the availability of cGMP grade PGC for use in prolonging the half life of various peptide drugs that are in p ...

    SBIR Phase II 2017 Department of Health and Human Services
  7. A Phase 2 clinical trial of topical uracil for the prevention of capecitabine induced hand-foot syndrome

    SBC: Nanometics LLC            Topic: 102

    Problem to be SolvedCapecitabine is a widely prescribed and orally available prodrug of the chemotherapeutic agentfluorouracilFUThe principle dose schedule limiting toxicity associated with its use is Hand Foot syndromeHFSand occurs inof patients receiving capecitabineHFS manifests in the hands and feet of patientsand rapidly progresses to painful peelingblisteringand bleeding that commonly requir ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  8. PREDICTIVE BIOMARKERS OF ADVERSE REACTIONS TO PROSTRATE CANCER RADIOTHERAPY

    SBC: L2 DIAGNOSTICS, LLC            Topic: NCI

    The overall objective of this project is to advance the development of a clinically usefully multiplex assay todetect biomarkers of radio sensitivity that will identify subsets of prostate cancer patients for whichradiotherapy should be contraindicated This assay will be capable of predicting the risk of developingadverse effects principally urinary morbidity and rectal injury resulting from ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  9. A Novel Tolerance Therapeutic for Treating Multiple Sclerosis

    SBC: VIRTICI LLC            Topic: NIAID

    Our goal is to develop VTC MSas a novel tolerance inducing therapeutic to treat Multiple SclerosisMSMS is the most common demyelinating disorder of the Central Nervous SystemCNSaffecting approximatelymillion people worldwide andin the US aloneCurrent and developing treatment of MS relies mainly on immuno suppression and modulation to reduce inflammatory symptoms creating a significant need for new ...

    SBIR Phase II 2017 Department of Health and Human Services
  10. Exploratory Clinical Study to Evaluate the Potential Bioactivity of CLBS14 in Patients with Coronary Microvascular Dysfunction

    SBC: NeoStem, Inc.            Topic: NHLBI

    Exploratory Clinical Study to Evaluate the Potential Bioactivity of CLBSin Patients with Coronary Microvascular Dysfunction Project Summary Abstract CLBSis an autologous cell therapy consisting of G CSF mobilized autologous CDcells obtained from peripheral bloodThe primary mode of action is improvement in perfusion by neo angiogenesis and or microvascular function under conditions of inadequate pe ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
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