Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until September, 2020.

  1. Kinetic Phenotype Discovery Informatics for Neurological Diseases

    SBC: DRVISION TECHNOLOGIES LLC            Topic: 101

    Project Summary Neurological disorders significantly outnumber diseases in other therapeutic areas and are growing in incidence faster than any other disease classesHoweverthe pharmaceutical industry has been unsuccessful in coming up with effective drugsA big factor in these failures has been a lack of adequate model systems for fundamental disease understanding affecting both diagnosis and treat ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Enabling point-of-care molecular diagnostics by developing an adaptive PCR instrument and on-demand kit reagents

    SBC: BIOVENTURES, INC            Topic: 172

    Because of its high sensitivitypolymerase chain reactionPCRis the gold standard for the diagnosis of many infectious diseasesbut generally only implemented in well equipped laboratoriesOne of the major roadblocks for expanding PCR to point of care markets is the lack of simplerobustsingle tube PCR designs which preserve its laboratory based high sensitivity and specificityIn this Fast Track STTR a ...

    STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Development of Chemistry, Manufacturing, and Control Standards for PGC and PGC-dANP

    SBC: PharmaIN Corporation            Topic: NHLBI

    ABSTRACTThis application is seeking funding specifically for ChemistryManufacturingand ControlCMCof scale up production of long acting atrial natriuretic peptidedANPand its protected graft co polymerPGCexcipient for use in heart failureHFtreatmentThe extrinsic merit of this project will be the availability of cGMP grade PGC for use in prolonging the half life of various peptide drugs that are in p ...

    SBIR Phase II 2017 Department of Health and Human Services
  4. PREDICTIVE BIOMARKERS OF ADVERSE REACTIONS TO PROSTRATE CANCER RADIOTHERAPY

    SBC: L2 DIAGNOSTICS, LLC            Topic: NCI

    The overall objective of this project is to advance the development of a clinically usefully multiplex assay todetect biomarkers of radio sensitivity that will identify subsets of prostate cancer patients for whichradiotherapy should be contraindicated This assay will be capable of predicting the risk of developingadverse effects principally urinary morbidity and rectal injury resulting from ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  5. A Novel Tolerance Therapeutic for Treating Multiple Sclerosis

    SBC: VIRTICI LLC            Topic: NIAID

    Our goal is to develop VTC MSas a novel tolerance inducing therapeutic to treat Multiple SclerosisMSMS is the most common demyelinating disorder of the Central Nervous SystemCNSaffecting approximatelymillion people worldwide andin the US aloneCurrent and developing treatment of MS relies mainly on immuno suppression and modulation to reduce inflammatory symptoms creating a significant need for new ...

    SBIR Phase II 2017 Department of Health and Human Services
  6. A Novel Peptide Therapeutic for Obesity

    SBC: VIRTICI LLC            Topic: 300

    Project Summary The goal of this project is to develop a novel peptide therapeuticVTC Gfor the treatment of obesityTodayone third of adults in the United StatesUSare obesewith an estimated annual healthcare burden of approximately $billionByit is projected that overof adults in the US will be obese with a yearly healthcare burden expected to exceed $billionwhich will account for approximatelyof th ...

    SBIR Phase II 2017 Department of Health and Human Services
  7. Development of an Open Speech Signal Processing Platform

    SBC: Flat Earth, Inc.            Topic: NIDCD

    This proposal will create an open speech signal processing platformThe open computational framework will be used for developing algorithms that will help accelerate acoustic and hearing science researchIt will permit researchers to more rapidly and easily test new algorithms with greater controlperformanceand easeSeveral example systems will be created to show that the platform can be adapted to a ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Practical high resolution microscopy of un-cut, un-embedded lung biopsies

    SBC: Applikate Technologies LLC            Topic: NCI

    Project Summary and Relevance The aim of this Phase II SBIR proposal from Applikate TechnologiesLLCis to build on the successful completion of our Phase I milestones with the designconstructionand testing of prototype devices and software for implementing the ClearView tissue histology system in clinical settings by laboratory personnelClearView is a novel approach to performing complete and non d ...

    SBIR Phase II 2017 Department of Health and Human Services
  9. A Hand-Held Robot to Cure BPH

    SBC: Virtuoso Surgical, Inc.            Topic: NIBIB

    Project Summary AbstractThe objective of this proposal is to transform a hand held surgical robotic system for transurethral laser prostate surgery from a lab prototype into a commercial productThe system will feature needle sized arms deployed through the endoscope port and will enable independent tissue manipulationlaser aimingand visualizationmaking surgery more accurate and ef cientClinical si ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Using Mobile Technology to Enhance MST Outcomes

    SBC: EVIDENCE-BASED PRACTICE INSTITUTE, INC.            Topic: 104

    PROJECT SUMMARY ABSTRACTEach yearover one million adolescents are arrestedmany more engage in other serious conduct problemsincluding binge drinkingillicit drug useand school drop outCollectivelythese problems result in enormous costs to individualsfamiliesand societyThe most effective interventions to address these problems are family basedwith a strong clinical emphasis on helping parents better ...

    SBIR Phase II 2017 Department of Health and Human Services
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