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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Nanoparticle Delivery System for Ewing Sarcoma Treatment
SBC: NANOVALENT PHARMACEUTICALS INC Topic: 102DESCRIPTION provided by applicant This Phase I STTR project seeks to demonstrate proof of principle that novel targetable nanoparticles can delivery therapeutic substances to human tumor cells and reduce tumor burden in metastatic cancer The concept for these nanoparticles is based on the polymerized liposome nanoparticle PLN that displays functional antibodies that target tumor cell surfac ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Monitored Breathing Awareness Therapy for Insomnia Disorder in Older Adults
SBC: ADVANCED MEDICAL ELECTRONICS CORP Topic: NIADESCRIPTION provided by applicant Insomnia of sufficient clinical severity to meet diagnostic criteria is present in approximately of older adults nearly million individuals n the US alone If left untreated it can lead to increased rates of depression cognitive impairment and cardiovascular disease Treatment relies on pharmacotherapy such as sedative hypnotic therapy which is ass ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Targeted Polymerized Shell Microbubbles to Image Surgical Adhesions
SBC: NANOVALENT PHARMACEUTICALS INC Topic: NIGMSDESCRIPTION provided by applicant The long term goal of this Phase I STTR project is to develop a commercially viable ultrasound contrast reagent UCR that will allow the noninvasive identification of newly forming abdominal adhesions after surgery Successful implementation would have significant impact because we would remove the impediment to clinical testing of anti adhesion therapies and ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Medical Sensor Applications of Tunnel Magnetoresistance TMR
SBC: Koronis Biomedical Technologies Corp. Topic: NIDCDDESCRIPTION provided by applicant Koronis Biomedical Technologies KBT proposes to develop a novel omnidirectional low power miniaturized hearing aid telecoil replacement module TCRM based on tunneling magnetoresistance TMR technology It has been reported that million Americans have hearing loss Hearing loss affects in Americans and in households Modern telecoils assist ...
STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health -
Selective inhibition of CYP26A1 in the skin for the treatment of ichthyosis
SBC: DERMAXON LLC Topic: NIAMSProject Summary Abstract DermaXon s project goal is to develop efficacious novel selective inhibitors of CYP A for the topical treatment of ichthyosis Congenital ichthyosis is a family of hereditary disorders of keratinization characterized by dry scaling skin that may be thickened or very thin impacting the quality of life of patients and their family members Currently there is no cure f ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Novel antibacterial agents derived from natural products
SBC: Promiliad Biopharma Incorporated Topic: NIAIDDESCRIPTION provided by applicant Antibiotic resistance among common bacterial pathogens is a serious public health problem as it compromises our ability to treat infectious disease The resistance problem is compounded by the lack of discovery of new antibiotics especially those with novel mechanisms of action New antibiotics are critically needed as resistance to recently developed antibiot ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
HELical Biodegradable Photochemical(HELP)Stents for AVF Maturation
SBC: Inovasc, LLC Topic: 300ABSTRACT Although arteriovenous fistulae AVFs are the preferred mode of dialysis vascular access over fail to mature in that they do not develop an adequate blood flow or diameter to support hemodialysis This results in a very significant clinical morbidity and economic cost At a pathogenetic level AVF maturation failure is due to a small vessels b bad non laminar hemodynamic pr ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Cancer Imaging and Therapy Platform
SBC: BIOINVISION INC Topic: 102Summary We will create a preclinical quantitative Cancer Imaging and Therapy Platform CITP which will allow one to study cancer biology and optimize pipelines of technologies imaging agents imaging methods targeted nano therapeutics tumor models etc especially for metastatic and invasive cancers Today primary tumor mass es are clinically controlled with surgical drug and radiatio ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Liver Surface Nodularity Score as a New Noninvasive Biomarker for Chronic Viral Hepatitis
SBC: ImageIQ, Inc. Topic: 300DESCRIPTION provided by applicant Chronic viral hepatitis is clinically silent until development of cirrhosis and hepatic decompensation Decompensated cirrhosis is a precursor to liver failure and is associated with increased risk of severe esophageal bleeding significant cardiovascular events and death The gold standard for diagnosing cirrhosis is liver biopsy though problems with the pro ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Directed Chemotherapy Delivery for Leptomeningeal Metastases
SBC: Minnetronix Medical, Inc. Topic: 102DESCRIPTION provided by applicant Directed Chemotherapy Delivery for Leptomeningeal Metastases PI Lad Shivanand and McCabe Aaron Project Summary Leptomeningeal Metastases LM is a condition in which cells from a primary solid or hematological tumor metastasize invade the subarachnoid space and spread throughout the cerebrospinal fluid CSF resulting in seeding of the leptomeninges along ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health