Award Data

Otitis media is a world wide disease primarily affecting the pediatric population under the age ofyearsIt is the most common reason for pediatric care visits and antibiotic therapyOver prescription and poorcompliance have led to a reduced susceptibility of bacteria to antibiotics andconsequentiallyto recurrent and chronic ear diseasesClearlythere is a compelling need to investigate alternative the ...

ABSTRACTUp toof low birth weight preterm infants manifest some form of periventricular white matter injuryPWMImaking it the most common form of brain injury affecting premature infantsPWMI is associated with significant morbidityas affected individuals may have profound intellectual impairment and cerebral palsyHighlighting the magnitude of PWMIeach year more thaninfants are born prematurely in th ...

Abstract Stress urinary incontinenceSUIcan result from a combinatorial neuromuscular injury to the pudendal nerve and the muscle it innervatesthe external urethral sphincterEUScompounded by the biochemical effects of agingThe mechanisms of SUI development include incomplete pudendal nerve regeneration and EUS sphincter repair from the maternal polytrauma of childbirth as well as biochemical change ...

Project Summary Age related macular degeneration remains the most common cause of permanent vision loss in the US and many industrialized countriesExtensive attention is paid to developing treatmentsresulting inregistered treatment trials in the USThe large numbers of patients and trials accentuates the need for improved biomarkers for the management of patientsFurtherif outcome measuresincluding ...

GravesdiseaseGDis the most common cause of hyperthyroidism and is caused by stimulation of the thyroid stimulating hormone receptorTSHRby thyroid receptor stimulating antibodiesTSAbsTreatment of GD involves antithyroid medication therapyradioactive iodineand surgeryAt the presentfew alternative forms of therapy for GD are available or are in developmentThe ability to block TSHR action may also be ...

Project SummaryAbstract This project will develop and test a publicly available web interface for executing and monitoring genomic data analysis pipelines described by the Workflow Description LanguageThe interface will be hosted on Truwl TMhttpstruwl comxD Bio s TMcommunity oriented genomic data analysis methods sharing web applicationExecuting pipelines will leverage the reproducibility framewor ...

Paper Spray mass spectrometry (PSMS) has been developed and commercialized for analysis of fluid samples by mass spectrometry. PSMS provides advantages over existing analysis techniques by reducing sample preparation needs and incorporating the sample storage and sample introduction to a single consumable device that is disposed after analysis, thus eliminating cross contamination and/or cleaning ...

Nanoparticles represent an attractive alternative in coating processes due to their functional versatility, including surface, optical, conductive and catalytic properties. However, current processes of coating textile products with nanoparticles results in rapid loss of the nanoparticles during laundering or use, leading to a significant decrease in product durability and functionality and increa ...

SIFT, JHU medicine and University of Central Florida are proposing to develop VANESSA (Virtual Analysis Networks and Explanations for Social Sensing Analysis) - a social sensing platform providing team diagnostics of interacting teams and recommendations for enhanced team functioning of human and human-cyber teams. The overall goal of VANESSA is to develop an adaptive technology platform with a fo ...

PROJECT SUMMARY This proposal responds to PAR-18-870 titled “BRAIN Initiative: Development Optimization, and Validation of Novel Tools and Technologies for Neuroscience Research (STTR).” This project is a Fast Track STTR with a phase I and phase II. The small business, Applied Universal Dynamics Corp. (AUD) is collaborating with the University of Minnesota (U of MN). The activity patterns of t ...