Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Collaborate

    SBC: Aufero LLC            Topic: 91990019R0011

    The team will develop a prototype of Collaborate, a traditional board game for use in high school and college level computer science courses. Gameplay mechanics will center on strategy and cooperation with a whole class over several weeks. Content will focus on foundational computer science topics, such user interface design, quality assurance, deploying resources, managing risk, and adjusting to ...

    SBIR Phase I 2019 Department of EducationInstitute of Education Sciences
  2. DNA Based Nanoparticle Platform for HIV Env Presentation

    SBC: PARABON NANOLABS, INC.            Topic: NIAID

    In this projectParabon NanoLabs and The Scripps Research Institute propose to develop and produce an effective HIVvaccine using a structured DNA origami nanocarrier for the targetedcontrolled delivery of a stabilizedtrimeric HIVenvelope glycoproteinEnvwith an integrated adjuvantThe project will begin with the synthesis and characterization of composite nanostructurePV NFLto include development and ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  3. IMPACT-Instrument to Measure Pain and Assess Correlation to Treatment. Create a smartphone pupillometry to objectively determine the presence of acute pain, evaluate opioid as the treatment for pain.

    SBC: Benten Technologies, Inc.            Topic: NIDA

    PROJECT SUMMARY ABSTRACT While patient self report of pain is currently the gold standard of pain measurementaccurate self reports of pain may not be feasible in critically ill patients who are sedated and intubatedunconscious patientsor patients who are unable to verbally communicate their painCurrent research has shown that pupillary dilationPDis a reliable indicator of acute painand that measur ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Healthy Close Relationships (HCR)- Mobile

    SBC: Research, Evaluation and Social Solutions, Inc. (REESSI)            Topic: NICHD

    ABSTRACT HEALTHY CLOSE RELATIONSHIPSHCRMOBILEGrowing up in under resourced environmentse gpovertylow incomegeographical isolationfragile family structurescan seriously threaten an adolescent s successful passage to adulthoodResearchers have uncovered very separate and unequal pathways to adulthood for adolescents one for thehavesone for thehave notsand a path for those who are in betweenThe networ ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. A cloud-based WGS platform for establishing phylogeny within epidemic outbreaks at hospitals

    SBC: ICBiome            Topic: NIAID

    Outbreaks have become a significant public threat in hospitalsimpacting both patient lives and creating a financial burdenWith the increasing rise in antibiotic resistancenew interventions are urgently needed to contain ongoing outbreaksRecent studies have confirmed that whole genome sequencingWGSis able to identity unique mutations within each outbreak strainwhich can then be utilized to establis ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Discovery of NaV1.7 Inhibitors for the Treatment of Pain

    SBC: Siteone Therapeutics, Inc.            Topic: 105

    PROJECT SUMMARY The objective of our program is to develop a safe and effective nonopioid analgesic for the treatment of neuropathic painsuch as pain associated with chemotherapy induced peripheral neuropathythat targets an isoform of the voltage gated sodium ion channelNaVVoltage gated sodium channels are involved in the transmission of nociceptive signals from their site of origin in the periphe ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Safety using Augmented reality to Facilitate Effective Training and Education (SAFE-TE). The objective of SAFE-TE is to support workers being trained to work with hazardous materials more efficiently

    SBC: Benten Technologies, Inc.            Topic: NIEHS

    PROJECT SUMMARY ABSTRACT The Occupational Safety and Health ActOSHAwas formed to protect workers and prevent work related injuriesOSHA standards include explicit safety and health training requirements to ensure that the workers have required skills and knowledge to do their work safelyBenten Technologies is partnering with the International Brotherhood of TeamstersIBTto help workers in the HAZMAT ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Developing small molecule PTP4A3 inhibitors for ovarian cancer

    SBC: KeViRx Inc            Topic: 102

    Project SummaryOur objective is to develop small molecule inhibitors of the highly oncogenic protein tyrosine phosphatasePTP Aas a targeted therapy for ovarian cancerOvCaElevated levels of PTP AmRNA and protein in ovarian tumors correlate with disease progression and recurrencepoor patient prognosis and poor patient survivalGenetic depletion of PTP Ain cancer cells diminishes their ability to surv ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Immunometabolic NLRX1 Therapeutics for IBD

    SBC: Biotherapeutics, Inc.            Topic: 300

    Immunometabolic NLRXTherapeutics for IBD Biotherapeutics IncBTIis an emerging biotech company that synergistically combines the power of advanced computational modeling with translational experimentation to accelerate the development of novel products for precision medicine and healthThis SBIR application stems from data showing a vital role for nucleotide binding oligomerization domainleucine ric ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Reducing Health Disparities among African American Women: A Mobile Cognitive Behavioral Stress Management Intervention

    SBC: ISA ASSOCIATES INC            Topic: NIMHD

    PROJECT SUMMARY ABSTRACTThe unjust socialeconomicand environmental conditions that all African Americans face throughout their lives leads to pervasive health disparitiesSubstandard medical care due to systematic bias in the healthcare system and a substantial wealth gap between Black and White households all lead to poorer healthAnd yetthe association between race and health persists even when co ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
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