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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Graspable Math Activities

    SBC: GRASPABLE INC            Topic: 91990018R0006

    Through previous grant awards from IES, researchers developed Graspable Math, a tablet-based intervention where middle and high school students create and manipulate complex expressions for basic operations as well as equations and equations systems and inequalities. In this project, the team will develop a prototype of Graspable Math Activities, an app with novel kinds of algebra practice and ass ...

    SBIR Phase I 2018 Department of EducationInstitute of Education Sciences
  2. Assistive Device to Improve Object Recognition and Reading

    SBC: Aeon Imaging, LLC            Topic: na

    The goal of this project is to create an affordable system for optimizing the use of assistive devices (tablets) to improve reading and object recognition performance for individuals with visual impairments. The objectives are: (1) to select a suitable assistive device that can be paired with Aeon’s existing Digital Light Ophthalmoscope (DLO-LV) vision research retinal camera which maps the posi ...

    SBIR Phase I 2018 Department of Health and Human Services
  3. Adherence Monitor for Substance Use Disorder Treatment


    Project Summary The focus of the present SBIR program is to determine the feasibility of a new noninvasivepoint of care testing device for patients undergoing treatment for substance use disorderThe new device will be capable of monitoring the progress and verifying adherence with patient treatment regimen by detecting the presenceand levelof a compounded adherence marker released in the urineprov ...

    SBIR Phase I 2018 Department of Health and Human Services
  4. Polymeric nanoparticles for inductive browning of white adipose tissue

    SBC: ADIPO THERAPEUTICS, LLC            Topic: 200

    Global epidemics of obesity and its associated comorbidities pose formidable challenges to human healthCurrent few medications available for obesity treatment only produce modest effects and are usually accompanied with unpleasantpotentially harmful side effectsThere is accumulating evidence that significant metabolic differences that distinguish beige brown adipocytes from white adipocytes can po ...

    SBIR Phase I 2018 Department of Health and Human Services
  5. Topical selective T-type blockers for the treatment of neuropathic pain

    SBC: Dermaxon LLC            Topic: 105

    Project SummaryAbstract Paclitaxel is widely used throughout the field of oncology with indications for the treatment of a number of solid tumorsThe most commonly reported neurotoxic effect of paclitaxel is peripheral sensory neuropathy which often limits the dose and frequency of paclitaxel treatmentNeuropathic pain management is currently aimed only at reducing symptoms and treatment of chronic ...

    STTR Phase I 2018 Department of Health and Human Services
  6. Development and feasibility of prevention-minded oral health mobile App based on dietary selections and oral hygiene events.

    SBC: Indiana Nanotech, LLC            Topic: NIDCR

    The number of decayed and filled tooth surfaces in primary dentition is on the rise in US children between the ages ofandyears oldin factof adolescentsbetweenandyears oldandout ofdentate seniorsagebear evidence of dental cariesReinforced with areport statingof those between the ages ofandhave dental cariesvirtually all walks of life are thus affectedand this doesn t even include those unreportedor ...

    SBIR Phase I 2018 Department of Health and Human Services
  7. Fluoroscopic drill attachment for orthopedic trauma surgery

    SBC: Eclipse Orthopaedics, LLC            Topic: NIAMS

    Abstract Aboutleg and hip fractures each year are treated by implanting a stiff metal rod or intramedullaryIMnailthrough the center of the bone and fixing the ends of the nail to the bone with screwsBut placing the locking screws to fix the rod to the bone is difficultTo anchor the nail securelythe surgeon must accurately drill pilot holes through both the bone and locking holes in the nailwhile t ...

    SBIR Phase I 2018 Department of Health and Human Services
  8. An Opioid/Cannabinoid Analgesic that Boosts Pain Relief and Blocks Opiate Reward

    SBC: ElSohly Laboratories, Incorporated            Topic: NIDA

    Project Summary Abuse of prescription opioids and fatalities related to their misuse have increased sharply in recent yearsmaking the development of pain medications with reduced abuse potential a major public health priorityWhen combinedopioids and cannabinoidCBreceptor agonists show analgesic effects appear to be at least additive in a number of pain modelsCannabidiolCBDalthough much less psycho ...

    STTR Phase I 2018 Department of Health and Human Services
  9. Software and services to advance does-response modeling in chemical risk assessment

    SBC: KS and Associates LLC            Topic: NCATS

    PROJECT SUMMARY Chemical risk assessment has been widely applied in chemical industry as a necessary step to get new commercial chemicals registeredand in governmental agencies as a critical procedure to evaluate the toxicity of chemicals in order to properly regulate them to protect human health and the environmentThe Lautenberg Chemical Safety Act further strengthens the importance of chemical r ...

    STTR Phase I 2018 Department of Health and Human Services
  10. Live Cell Assays to Identify and Interrogate Stressed Neurons in Models of Neurodegenerative Disease.

    SBC: Montana Molecular LLC            Topic: 105

    Summary Abstract Many diseases of the brain involve cellular stressEarly in lifethe Zika virus triggers stress in neural progenitor cells causing microcephalyMuch later in life the mutant proteins produced in Parkinsonandapos s and Huntingtonandapos s diseaseas well as ALSand Alzheimerandapos s all produce cellular stress leading to the slow neurodegeneration that occurs over many yearsTypically t ...

    SBIR Phase I 2018 Department of Health and Human Services

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