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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Tumor Antigen Targeted Nanoparticle Therapy for Glioblastoma (GBM)
SBC: NANOVALENT PHARMACEUTICALS INC Topic: 102Project Summary The goal of this Fast Track STTR project is to determine proof-of-principle and efficacy of a novel blood brain barrier (BBB) penetrating therapeutic nanoparticle for the potential treatment of otherwise intractable brain tumors like glioblastoma multiforme (GBM). This project seeks to demonstrate that novel, targetable nanoparticles can delivery therapeutic substances to human bra ...
STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
Image-based risk assessment to identify women at high-risk for breast cancer
SBC: WAVED MEDICAL LLC Topic: NCI7. PROJECT SUMMARY Breast cancer is the most common cancer worldwide and the most common cancer diagnosed in American women. While there has been good progress regarding detection and treatment methods, breast cancer remains the primary cause of death from malignant tumors. Hence, there is a critical need for the development of novel predictive and prognostic factors. Risk assessments are currentl ...
STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
Prapela® SVS incubator pad: A cost-effective stochastic vibrotactile device to improve the clinical course of infants with apnea of prematurity.
SBC: PRAPELA INC Topic: NIDAPrapela proposes to complete the development of and then establish the safety, efficacy, and clinical risk/benefit of a novel hospital incubator pad that will provide a complementary treatment and the first improvement in the clinical management of apnea of prematurity (AOP) in over 20 years. Defined as cessation of breathing for 20 seconds or longer or a shorter pause accompanied by hypoxemia, AO ...
SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
Booth™ by Opio™: Developing technology to expand the reach of opioid treatment programs into rural and underserved areas.
SBC: Opio Connect, Inc. Topic: NIDAThe goal of this project is to develop a treatment booth with technology that allows opioid treatment programs to remotely dispense, either methadone or buprenorphine, under medical observation through telemedicine to a patient in a treatment booth. We believe that robotic automation is the ideal application to perform the same mechanical functions of the nurse at the dosing window. Specifically, ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Pharmacogenomics Workflow: Identifying Biomarkers and Treatment Options
SBC: Golden Helix, Inc. Topic: 172Abstract Pharmacogenomics, the study of how an individual's genetic makeup affects their response to drugs, has undergone rapid advancements. This has occurred alongside a decrease in the cost of genotyping technology, making implementation of pharmacogenomics into clinical practice increasingly feasible. Personalized medicine leveraging pharmacogenomics is gaining momentum to optimize drug choice ...
SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
RAE cHealth:A digital community support tool to promote recovery from substance use disorder
SBC: CONTINUEYOU, LLC Topic: NIDAPROJECT SUMMARY The research project outlined in this Fast track SBIR submission will develop the RAE cHealth platform into a tool to address digital inequities and support peer-based collaborative recovery for individuals with substance use disorder. In this proposal, the investigators intend to develop and deploy the RAE cHealth system- consisting of a wearable sensor and a smartphone app. RAE c ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Selective CYP26 inhibitors for the oral treatment of recalcitrant nodular acne.
SBC: DERMAXON LLC Topic: NIAMSProject Summary / Abstract DermaXon's project goal is to develop efficacious, substrate-based, selective inhibitors of CYP26s, the enzymes responsible for the metabolism of all-trans retinoic acid (atRA) in the epidermis, as an oral treatment for severe recalcitrant acne. This approach will provide an improved acne therapeutic without the adverse effects associated with currently marketed retinoid ...
SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
Large-scale Additive Manufacturing R&D to Advance Modular Shelter Design and Deployment
SBC: Compotech, Inc. Topic: A22013Shelter system technologies provide vital support to U.S. military personnel during in-theatre operations and peace-time continuity. Soldiers, logistics experts, and decision makers across the chain of command require shelter systems that perform in austere environments while also being cost-effective, resilient, durable, and easily maintained. For land-based conflicts in more remote locations and ...
SBIR Phase I 2023 Department of DefenseArmy -
DETECT-ML: Detection of Energetic Topology Errors via Computed Tomography & Machine Learning
SBC: Compotech, Inc. Topic: A224013Compotech, Inc. seeks to build on our award winning FRAG-CT munition characterization method by developing a new complementary software and hardware package to provide rapid, real-time defect detection at the heart of a munition’s explosive core. The detection technique leverages proven AI/ML detection software algorithms and high speed CT scanning equipment.
SBIR Phase I 2023 Department of DefenseArmy -
Spray Dried Powder Compositions for Dual-use Secondary High Explosive and Rocket Propellants
SBC: DIVISION BY ZERO DEVELOPMENT LABS LLC Topic: A21CT001The U.S. Army has a future need for multiple secondary high explosive compositions that can also be used interchangeably as rocket propellants. In this proposal we will discuss a method of preparing such compositions via advanced spray drying technology and involving the use of a highly insensitive spray dried nitramine or CL-20 composition which have been plasticized with an energetic polymer t ...
STTR Phase I 2022 Department of DefenseArmy