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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Ultrasensitive Nonisotopic Detection of RNA

    SBC: AMBION DIAGNOSTICS, INC.            Topic: N/A

    Nonisotopic calorimetric and chemiluminescent technologies will be developed for use withribonuclease protection assays. The ribonuclease protection assay is an increasingly utilized techniquein molecular biology affording sensitive and quantitative measurement of mRNA levels. The ability ofthe assay to detect multiple mRNA levels simultaneously makes this technique a unique and powerfultool for u ...

    SBIR Phase II 1996 Department of Health and Human Services
  2. "Rolling Deflectometer"

    SBC: Applied Research Associates, Inc.            Topic: N/A

    N/A

    SBIR Phase II 1996 Department of Transportation
  3. Semiautomatic, Quantitative Analysis of Funds

    SBC: APPLIED SCIENCES LABORATORY, INC.            Topic: N/A

    N/A

    SBIR Phase II 1996 Department of Health and Human Services
  4. Design of Specialized Protocol Software

    SBC: Ck Software, Inc.            Topic: N/A

    This proposal addresses the need to develop products which will help participants in health care assquality and level of care furnished to patients. We will develop a prototype ¿Protocol Engine¿, withdesigned for personal computers and computer networks, to allow protocols to be defined and customizspecific needs of the organization; to link and/or access data from other medical software package ...

    SBIR Phase II 1996 Department of Health and Human Services
  5. Construction of Synthetic Muscle Specific Promoters

    SBC: Genemedicine, Inc.            Topic: N/A

    Somatic gene therapy is expected to provide new and improved therapies for many diseases.We are developing a new class of DNA-based therapeutics, "gene medicines" which are expected toprovide unique clinical benefits for the treatment of a broad range of diseases. Gene medicines utilizetissue-specific DNA expression vectors and novel vector delivery systems for the in vivo delivery oftherapeutic p ...

    SBIR Phase II 1996 Department of Health and Human Services
  6. Molecular Switch for Controlled Gene Therapy

    SBC: Genemedicine, Inc.            Topic: N/A

    This application describes construction of a vector for a gene therapy that can be incorporatedinto somatic cells in vivo and then regulated by administration of an oral, non-toxic, and widelybioavailable drug. The "gene switch" is based on a derived mutant of the progesterone receptor thatis activated by progesterone antagonists, but is not activated by progesterone agonists or other steroids.Thi ...

    SBIR Phase II 1996 Department of Health and Human Services
  7. Expression of Dengue Viral Proteins in Drosophila Cells

    SBC: HAWAII BIOTECH, INC.            Topic: N/A

    Dengue virus causes dengue fever, a debilitating illness marked by high fever, headache, muscleand joint pain, and rash. The more severe forms of the illness, dengue hemorrhagic fever and dengueshock syndrome, are life threatening and are a principal cause of hospitalization among children inSoutheast Asia. Globally, the four serotypes of dengue are responsible for up to 100 million infectionsannu ...

    SBIR Phase II 1996 Department of Health and Human Services
  8. Phage Displayed Antibodies to C. botulinum toxin A

    SBC: HAWAII BIOTECH, INC.            Topic: N/A

    The neurotoxins of Clostridium botulinum are the most lethal proteins known. The bacterium is ubiquitous, and thus rapid, reliable, sensitive, and cost-effective assays are needed to detect the toxin. Current immunoassays provide a rapid means to detect the neurotoxin. Their sensitivity, however, is limited by the affinity of the detecting antibody. The objective of this research, therefore, i ...

    SBIR Phase II 1996 Department of DefenseArmy
  9. Ultrasonic Cardiovascular Measurements in Small Animals

    SBC: INDUS INSTRUMENTS            Topic: N/A

    Genetic manipulation is a developing tool in cardiovascular research, and much of this work isdone in mice. Ultrasound equipment designed for use on humans is not suitable for non-invasivemonitoring of cardiovascular parameters in mice due to small organ size (5 mm dia heart) and high heartrates (400-600 bpm). We propose to develop an instrument to measure cardiac output and myocardialfunction non ...

    SBIR Phase II 1996 Department of Health and Human Services
  10. Image Processing Using Temporal Cellular Neural Networks

    SBC: Intelligent Reasoning Systems (IRS)            Topic: N/A

    This proposal addresses the development of a compact, high-speed camera system that integrates a Charge-Coupled Device (CCD) solid-state imager and a Temporal Cellular Neural Network (TCNN) (using three-dimensional TC technology) to provide real-time image processing capability for scientific and engineering applications. The integrated CCD/TCNN camera provides high-speed image collection and proc ...

    SBIR Phase II 1996 Department of DefenseArmy
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