Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Design of Specialized Protocol Software

    SBC: Ck Software, Inc.            Topic: N/A

    This proposal addresses the need to develop products which will help participants in health care assquality and level of care furnished to patients. We will develop a prototype ¿Protocol Engine¿, withdesigned for personal computers and computer networks, to allow protocols to be defined and customizspecific needs of the organization; to link and/or access data from other medical software package ...

    SBIR Phase II 1996 Department of Health and Human Services
  2. Expression of Dengue Viral Proteins in Drosophila Cells

    SBC: Hawaii Biotech, Inc.            Topic: N/A

    Dengue virus causes dengue fever, a debilitating illness marked by high fever, headache, muscleand joint pain, and rash. The more severe forms of the illness, dengue hemorrhagic fever and dengueshock syndrome, are life threatening and are a principal cause of hospitalization among children inSoutheast Asia. Globally, the four serotypes of dengue are responsible for up to 100 million infectionsannu ...

    SBIR Phase II 1996 Department of Health and Human Services
  3. Expert System for Recombinant DNA Invention Disclosure

    SBC: Yellowstone Environmental            Topic: N/A

    The information produced by the Human Genome Project and related research is expected torevolutionize biology and medicine in general and recombinant DNA technology in particular. At present,however, obtaining patent protection for inventions involving recombinant DNA technology is anacknowledged bottleneck in the development of the U.S. biotechnology industry. While much attentionhas been focused ...

    SBIR Phase II 1996 Department of Health and Human Services
  4. Phage Displayed Antibodies to C. botulinum toxin A

    SBC: Hawaii Biotech, Inc.            Topic: N/A

    The neurotoxins of Clostridium botulinum are the most lethal proteins known. The bacterium is ubiquitous, and thus rapid, reliable, sensitive, and cost-effective assays are needed to detect the toxin. Current immunoassays provide a rapid means to detect the neurotoxin. Their sensitivity, however, is limited by the affinity of the detecting antibody. The objective of this research, therefore, i ...

    SBIR Phase II 1996 Department of DefenseArmy
  5. Optimal Synthesis of Benzodiazepine Glucuronide

    SBC: Synthetic Technology            Topic: N/A

    Benzodiazepines are in clinical use as antianxiety agents and are controlled substances. Prolonged use may be habit forming. Benzodiazepine abuse is a widespread problem. There is a practical need to screen for the presence of benzodiazepines and their metabolites. Oxazepam glucuronide is the final metabolite of oxazepam and related benzodiazepines in humans and other species. It may be used in th ...

    SBIR Phase II 1995 Department of Health and Human Services
  6. Heat Stable Alkaline Phosphatase from Thermophiles

    SBC: J.k. Research            Topic: N/A

    Enzymes used as the label for most non-radioactive assays and in biosensors, are the most unstable component of these systems. As immunoassays and biosensors move from the tightly controlled laboratory environment to demanding field conditions, the need for a more stable enzyme becomes critical. Alkaline phosphatase is the most widely used enzyme for these types of applications. A heat stable enzy ...

    SBIR Phase II 1995 Department of DefenseArmy
  7. COGNITIVE SKILL-BASED CHILD-PROOF MEDICINE CONTAINER

    SBC: Yellowstone Environmental            Topic: N/A

    IN 1985, 900,513 POISONINGS--328 FATALITIES--WERE REPORTED TO THE AMERICAN ASSOCIATION OF POISON CONTROL CENTERS. SIXTY-FOUR PERCENT INVOLVED CHILDREN UNDER AGE SIX. SEVENTEEN PERCENT OF 2,015 PRESCRIPTION DRUG INGESTIONS INVOLVED GRANDPARENTS' DRUGS. RECENT STUDIES HAVE CONFIRMED THAT MANY ELDERLY HAVE TROUBLE OPENING CHILD-PROOFCONTAINERS. THE OBJECTIVE OF THIS RESEARCH IS TO ESTABLISH THE TECHN ...

    SBIR Phase II 1990 Department of Health and Human Services
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