Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Waterproofing Cargo Airdrop Equipment

    SBC: RESODYN CORPORATION            Topic: A16114

    The U.S. Army is interested in the development of innovative coating technologies to allow current U.S. Army airdrop related hardware and equipment to survive fresh and salt water operations with increased reliability and without damage and significant maintenance impact. Resodyn Corporation proposes for development a durable, moisture-impermeable, thermoplastic coating material to address the U.S ...

    SBIR Phase II 2019 Department of DefenseArmy
  2. Lead Acid Battery Monitoring, Diagnostics, and Prognostics

    SBC: Oceanit Laboratories, Inc.            Topic: A17023

    In this Phase II, Oceanit proposes to further the impedance approach and battery analyzer device developed in Phase I to demonstrate an optimized technique for monitoring, diagnosis and prognosis of lead acid batteries. Oceanit shall design an integrated lead-acid battery health monitoring tool prototype for testing in an operationally relevant environment. Impedance model will be further refined ...

    SBIR Phase II 2019 Department of DefenseArmy
  3. Discovery of new small molecule TLR4 agonists for the treatment of allergic rhinitis

    SBC: DiaCarta            Topic: NIAID

    This pilot study is aimed at judging the efficacy of the lead compound with a clinically relevant allergenThe relevant allergen chosen for this study is the house dust mite Dermatophagoides pteronyssinus allergenDer pLoToxTM Natural Der pfrom Indoor Biotechnologies with a low endotoxin contentEUgWe are selecting this allergen because our team has extensive prior experience with this allergen in mo ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Acoustic Scaffold Bioreactor

    SBC: RESODYN CORPORATION            Topic: NHLBI

    This Small Business Innovation Research Phase II project will develop a commercially viable device that uses micro scale acoustic streaminglow frequency sound energyto deliver mixing to the interior of three dimensionalDscaffolds used for stem cell cultivation applicationsThe enabling advantage of low frequency sound energy is the ability to generate micro scale mixing in and around scaffolds that ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Adherence Monitor for Substance Use Disorder Treatment

    SBC: YELLOWSTONE SCIENTIFIC INSTRUMENTS            Topic: NIDA

    Project Summary The aim of the present SBIR program is to develop a new noninvasivepoint of care testing device for patients undergoing treatment for substance use disorderThe new device will be capable of monitoring the progress and verifying patient adherence to prescribed treatment by detecting the presence and level of a compounded adherence marker released in the urineproviding for the first ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Novel antibacterial agents derived from natural products

    SBC: Promiliad Biopharma Incorporated            Topic: NIAID

    SPECIFIC AIMSAntibiotic resistance among common bacterial pathogens is a serious public health problem as it compromises our ability to treat infectious diseaseThe resistance problem is compounded by the relative lack of discovery of new antibioticsespecially those with novel mechanisms of actionNew antibiotics are critically needed as resistance to recently developed antibiotics is growingThe goa ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Novel synthetic TLR4 agonists

    SBC: INIMMUNE CORP            Topic: NIAID

    Project SummaryThere are currently no approved vaccines for most emerging biological pathogensEbolaChikungunyaMERS CoVSARSZikaopportunistic infectionsSaureusCandidiasisadenovirusor potential bioterrorism agentsYpestisBPseudomalleiFtularensisBunyaviridaeFlaviviridaeand therapeutic interventions such as antibiotics and antivirals are only effective for a select few pathogensA promising approach for ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  8. A robust assay for detecting agonist bias in living cells.

    SBC: Montana Molecular LLC            Topic: 300

    ! Project Summary The objective of this SBIR Phase II project is to optimize and validate a prototype assay for ligand bias to be used in screening drugs that target seven transmembrane Gprotein coupled receptorsGPCRsThe assay is based on genetically encoded fluorescent biosensors that report signaling with a change in fluorescence intensityAimof this project involves engineering and testing to in ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  9. NV103: Antibody Conjugated Nanoparticle for Ewing Sarcoma Targeted Therapy

    SBC: NanoValent Pharmaceuticals, Inc.            Topic: 102

    Project Summary This Phase II SBIR project seeks to demonstrate that noveltargetable nanoparticles can delivery therapeutic substances to human tumor cells and reduce tumor burden in cancerThe concept for these nanoparticles is based on the hybrid polymerized liposome nanoparticleHPLNthat displays functional antibodies that target tumor cell surface markersThe therapeutic cargos are encapsulated c ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Cross-Protective Multivalent Vaccine for Tick-Borne Flaviviruses

    SBC: Hawaii Biotech, Inc.            Topic: NIAID

    Project Summary AbstractThe NIH NIAIDStrategic Plan is specifically directed at promoting research that can provide solutions to mitigate the threat posed by emerging and re emerging diseasesThe tick borne flavivirusTBFVgroup includes a number of important human pathogens that result in serious neurological or hemorrhagic diseases that are either Category B or C priority pathogensThe TBFVs are con ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
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