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The major goal of this Phase II effort is to develop an embedded CLBT process force/sustainment flow analysis system that supports a tight integration between sustainment and force flows at the ISB. The general technical approach of the proposed IFAS2 (Integrated Force And Sustainment Flow Analysis System) is to exploit a distributed workflow framework augmented with a Bayes Net probability ne ...

The overall goal of the Phase I effort is to develop Intermediate Staging Base (ISB) planning capabilities. To achieve this goal, we identified three major objectives. The first objective is to arrange assets on the ISB as to optimize support for ISB customers. We examined the utility of Genetic algorithms towards this purpose and examined several optimization criteria and studied their effects o ...

DESCRIPTION (provided by applicant): This project will further develop automated instrumentation and image analysis techniques to detect gene duplications or deletions in interphase FISH, which are difficult to detect by routine cytogenetics. There is a

DESCRIPTION (provided by applicant): This project will further develop and refine an innovative digital auto-focus technology for automated microscopy. Auto-focusing is essential to automated microscope imaging. Currently available techniques rely on v

DESCRIPTION (provided by applicant): Postural control requires a complex interaction of visual and proprioceptive sensory inputs in addition to that provided by the vestibular system. A discrepancy produces a sensory mismatch and can result in seasickn

DESCRIPTION (provided by applicant): Fluorescent semiconductor nanocrystals or quantum dots have many properties that make them superior to traditional dyes as fluorescent markers. Quantum dots have higher extinction coefficients making them brighter

Because many chemical and biological toxins selectively target respiratory endothelial cells, a biosensor using these cells in combination with Electric Cell-substrate Impedance Sensing (ECIS) technology has many useful applications for detection and early warning monitoring of a broad range of toxic agents. In the Phase I SBIR program, Agave BioSystems was highly successful in demonstrating that ...

DESCRIPTION (provided by applicant): Research Objectives: Determine the safety, pharmacokinetics, pharmacodynamics, and efficacy of topical recombinant human lactoferrin (rhLF) in promoting healing in diabetic ulcers. There are 7.5 million U

DESCRIPTION (provided by applicant): In the past several years, a significant need has arisen to analyze bacterial gene expression following interactions with host cells in vivo. In vivo whole genome expression analyses are seen as crucial for identif

DESCRIPTION (provided by applicant): The purpose of this proposal is to develop a protein assay technology that will parallel the newly developing oligonucleotide microarray techniques. We will develop a peptide system capable of performing high throughput real time measurements in parallel on a microfluidic chip. We will develop the chemistry to prepare these chips in Phase I and develop the s ...