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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Discovery of new small molecule TLR4 agonists for the treatment of allergic rhinitis
SBC: DiaCarta, Inc. Topic: NIAIDThis pilot study is aimed at judging the efficacy of the lead compound with a clinically relevant allergenThe relevant allergen chosen for this study is the house dust mite Dermatophagoides pteronyssinus allergenDer pLoToxTM Natural Der pfrom Indoor Biotechnologies with a low endotoxin contentEUgWe are selecting this allergen because our team has extensive prior experience with this allergen in mo ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
Acoustic Scaffold Bioreactor
SBC: RESODYN CORPORATION Topic: NHLBIThis Small Business Innovation Research Phase II project will develop a commercially-viable device that uses micro-scale acoustic streaming (low frequency sound energy) to deliver mixing to the interior of three-dimensional (3D) scaffolds used for stem cell cultivation applications. The enabling advantage of low frequency sound energy is the ability to generate micro-scale mixing in and around sca ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
Adherence Monitor for Substance Use Disorder Treatment
SBC: YELLOWSTONE SCIENTIFIC INSTRUMENTS Topic: NIDAProject Summary The aim of the present SBIR program is to develop a new noninvasive, point-of-care testing device for patients undergoing treatment for substance use disorder. The new device will be capable of monitoring the progress and verifying patient adherence to prescribed treatment by detecting the presence and level of a compounded adherence marker released in the urine, providing for the ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
Novel antibacterial agents derived from natural products
SBC: Promiliad Biopharma Incorporated Topic: NIAIDSPECIFIC AIMSAntibiotic resistance among common bacterial pathogens is a serious public health problem as it compromises our ability to treat infectious disease. The resistance problem is compounded by the relative lack of discovery of new antibiotics, especially those with novel mechanisms of action. New antibiotics are critically needed as resistance to recently developed antibiotics is growing. ...
STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
Novel synthetic TLR4 agonists
SBC: INIMMUNE CORP Topic: NIAIDProject SummaryThere are currently no approved vaccines for most emerging biological pathogens (Ebola, Chikungunya, MERS CoV, SARS, Zika), opportunistic infections (S. aureus, Candidiasis, adenovirus) or potential bioterrorism agents (Y. pestis, B. Pseudomallei, F. tularensis, Bunyaviridae, Flaviviridae), and therapeutic interventions such as antibiotics and antivirals are only effective for a sel ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
A robust assay for detecting agonist bias in living cells.
SBC: MONTANA MOLECULAR LLC Topic: 300! Project Summary The objective of this SBIR Phase II project is to optimize and validate a prototype assay for ligand bias to be used in screening drugs that target seven transmembrane G- protein coupled receptors (GPCRs). The assay is based on genetically-encoded fluorescent biosensors that report signaling with a change in fluorescence intensity. Aim 1 of this project involves engineering and t ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
NV103: Antibody Conjugated Nanoparticle for Ewing Sarcoma Targeted Therapy
SBC: NANOVALENT PHARMACEUTICALS INC Topic: 102This Phase II SBIR project seeks to demonstrate that novel, targetable nanoparticles can delivery therapeutic substances to human tumor cells and reduce tumor burden in cancer. The concept for these nanoparticles is based on the hybrid polymerized liposome nanoparticle (HPLN) that displays functional antibodies that target tumor cell surface markers. The therapeutic cargos are encapsulated cytotox ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
Automated and Guided Workflows for Clinical Testing Using NGS Assays
SBC: Golden Helix, Inc. Topic: 400The work done in a genetic laboratory to process a sample requires many detailed-oriented steps and a wealth of individual and institutional knowledge. The output of this process often has a significant impact on a patient’s outcome and wellbeing. At the same time, the work is repetitive and requires the handling of large test volumes under the time pressures inherent in medical procedures. This ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
Dual-Mode Continuous-Wave Ladar and Optical Communications System
SBC: Bridger Photonics, Inc. Topic: A12089Because the data products generated by modern imaging ladar systems are inherently large in information content, there is currently a severe bottleneck in the communications of these products to end users, particularly when full-waveform recovery is desired. During the Phase I effort, Bridger demonstrated that their 3D imaging system architecture was ideally suited for seamless integration of high ...
SBIR Phase II 2014 Department of DefenseArmy -
The Most Efficient (TME) Cold Chain Container for Blood
SBC: RESODYN CORPORATION Topic: A12113Resodyn Corporation proposes to develop a novel cold chain system with a Lifetime Warranty (20+ years) for the vacuum container.The container is composed of a passive energy efficient system for transporting blood and pharmaceuticals in hostile environments for up to three days.Capacity is four unit blood transfusion bags.Energy efficiency is possible by the novel shape and super insulating qualit ...
SBIR Phase II 2014 Department of DefenseArmy