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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Dual-Mode Continuous-Wave Ladar and Optical Communications System

    SBC: Bridger Photonics, Inc.            Topic: A12089

    Because the data products generated by modern imaging ladar systems are inherently large in information content, there is currently a severe bottleneck in the communications of these products to end users, particularly when full-waveform recovery is desired. During the Phase I effort, Bridger demonstrated that their 3D imaging system architecture was ideally suited for seamless integration of high ...

    SBIR Phase II 2014 Department of DefenseArmy
  2. The Most Efficient (TME) Cold Chain Container for Blood

    SBC: RESODYN CORPORATION            Topic: A12113

    Resodyn Corporation proposes to develop a novel cold chain system with a Lifetime Warranty (20+ years) for the vacuum container.The container is composed of a passive energy efficient system for transporting blood and pharmaceuticals in hostile environments for up to three days.Capacity is four unit blood transfusion bags.Energy efficiency is possible by the novel shape and super insulating qualit ...

    SBIR Phase II 2014 Department of DefenseArmy
  3. Glycoengineered baculoviruses for the production of more efficacious influenza va

    SBC: Glycobac, LLC            Topic: NIAID

    DESCRIPTION (provided by applicant): Vaccination significantly reduces morbidity and mortality caused by annual influenza epidemics. Traditionally, influenza vaccines have been manufactured using adapted influenza virus grown in eggs. However, this methodsuffers from inherent disadvantages such as slow production and allergenic egg proteins in the final product. To avoid these drawbacks, new vacci ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. On Site Mercury Remediation via Activated Fly Ash

    SBC: POLLUTION CONTROL TECHNOLOGIES, LLC            Topic: NIEHS

    DESCRIPTION (provided by applicant): Coal-fired power plants and burners are vital drivers of the U.S. economy-but they unfortunately produce substantial amounts of mercury (Hg) that are seriously harmful to human health, particularly linked to damages ofthe nervous system. Healthcare costs due to Hg exposure are estimated to be in the billions of dollars annually. New mercury-emission regulations ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Engineering cells for concurrent protein drug biosynthesis and polysialylation

    SBC: Glycobac, LLC            Topic: NIGMS

    Project Summary / Abstract Therapeutic proteins, or biologics, represent a 100 billion market that includes drugs such as antibodies, hormones, and many others. The clinical efficacy of biologics is critically determined by their circulating half-lives.Hence, various methods have been developed to increase their circulating half-lives by reducing clearance rates. This is commonly achieved by che ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Co-axial Microinjection System for Freezing and Biopsy of Early Embryos

    SBC: GENESEARCH, INC.            Topic: 100

    DESCRIPTION provided by applicant The Dracula Pipette is a co axial embryo microinjection tool with the injection pipette presented from inside the holding pipette Double nested tips seal against the surface of the spherical embryo when a vacuum is applied in the space between them This allows a portion of the nearside surface of an embryo to be held by vacuum while a glass pipette is passed ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Fast and Accurate Tools for Measuring Fluorescence in Living Cells

    SBC: MONTANA MOLECULAR LLC            Topic: 106

    DESCRIPTION provided by applicant Specific information about the state of second messengers in drug signaling pathways is key to understanding the mechanism of a drug within the cell The largest class of drug targets is the G Protein Coupled Receptor GPCR and over of all prescription pharmaceuticals target a GPCR These proteins are the focus of many drug discovery programs because they ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Multi-Media Imagery Program for Breast Cancer Patients

    SBC: MIND MATTERS RESEARCH            Topic: N/A

    DESCRIPTION (provided by applicant): The specific aim of this Phase I SBIR project is to establish the technical merit and feasibility of producing a modular imagery intervention program for breast cancer patients and survivors that can be delivered to patients in a classroom setting, and/or at-a-distance, via Internet. Phase I prototype will emphasize feasibility of delivery and potential efficac ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  9. Transdermal Delivery of Anti-Malarial Drug

    SBC: RESODYN CORPORATION            Topic: A04201

    This Phase I proposal is aimed to develop a technology to delivery lipophilic therapeutic ingredients in broad and antimalarial drug primaquine in specific through skins. The proposed driving force of delivering target drugs is the opposite chemical affiliation of storage copolymer matrix and active therapeutic ingredient. The technology includes the formulation of patches - hydrophilic polymers, ...

    SBIR Phase I 2005 Department of DefenseArmy
  10. Development of an Acoustic Biological Shaker

    SBC: RESODYN CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): This Small Business Innovation Research Phase I project will demonstrate the feasibility of using ResonantAcoustics (low-frequency acoustic mixing) as the basis for developing a highly efficient laboratory scale ResonantAcoustic Biological Shaker (RBS). Conventional biological orbital shakers have substantial drawbacks that include low oxygen transfer capabilit ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
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