Award Data

WE WILL DEVELOP AN AUTOMATED LOW-TO-MODERATE COST "INTELLIGENT" EVOKED POTENTIAL MONITORING SYSTEM FOR USE IN OPERATING ROOMS AND INTENSIVE CARE UNITS. EVOKED POTENTIAL MONITORING IS DESIRABLE IN OPERATING ROOMS AND INTENSIVE CARE UNITS FOR THE PURPOSE OF RAPID DETECTION OF DELETERIOUS NEUROLOGICAL CHANGES THAT, IF UNRECOGNIZED AND UNCORRECTED, COULD LEAD TO SIGNIFICANT NEUROLOGICAL DEFICITS. AT P ...

VARIOUS ACTIVITIES (EDUCATION, GOVERNMENT, RESEARCH) GENERATE LARGE AMOUNTS OF RAW DATA. HOWEVER, DATA IS COLLECTED IN A DISJOINTED AND ISOLATED FASHION (I.E., ACTS, LITERATURE) CREATING BARRIERS IN DATA ACCESS AND DISSEMINATION. THERE IS A CONSENSUS AMONG FAMILIES AND PROFESSIONALS, THAT NEEDS OF INDIVIDUALS WITH DISABILITIES AND SERVICES PROVIDED TO THESE INDIVIDUALS COULD BE GREATLY IMPROVED IF ...

Our goal is to extend the Prophet system to include new data visualization capabilities. The new data visualization capabilities will assist investigators in detecting significant patterns in large bodies of pre-clinical and clinical data. The Phase I effort consisted of five tasks: (1) a Visualization Technology Review to ensure that the best possible results are achieved, (2) to conduct a survey ...

CIRCULATORY ASSIST DEVICES ARE NEEDED FOR IMMEDIATE TEMPORARY TREATMENT OF ACUTE MYOCARDIAL INFARCTION AND FOR SOME POSTCARDIOTOMY PATIENTS. IMPLANTED CIRCULATORY ASSIST DEVICES ALSO ARE BEING DEVELOPED FOR LONGER TERM HELP TO AMBULATORY PATIENTS WITH CHRONIC HEART FAILURE. PNEUMATIC AND ELECTROMAGNETICALLY ACTUATED PULSATILE ASSIST DEVICES HAVE BEEN INVESTIGATED, AND IN RECENT YEARS THERE HAS BEE ...

Recent studies have shown that light has surprising neuroendocrine and anti-depressant effects in humans. Prompted by these findings, a UCSD group has three times replicated a 1967 study by Dewan showing that an ordinary bedside light can influence menstrual cyclicity. Before we can even begin to research the parameters of light effects in reproductive medicine, more sophisticated lighting devices ...

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THE GOAL OF THIS PROJECT IS TO DEVELOP AN ARRAY OF 10-(4)CM(2) ELECTRODES FOR USE WITH A NEW INSTRUMENTAL METHOD FOR TISSUE CULTURE. THE METHOD, REFERRED TO AS ECIS (ELECTRIC CELL-SUBSTRATE IMPEDANCE SENSOR), IS A NON-INVASIVE TECHNIQUE TO MEASURE SEVERAL IN VITRO CELL PARAMETERS THAT HAVE PREVIOUSLY BEEN DIFFICULT TO QUANTIFY. THESE INCLUDE CELL MOTILITY, ADHESION AND SPREADING, MORPHOLOGY, AND T ...

FETAL MONITORING IS USEFUL IN ASSESSING THE PROGRESS OF LABOR AND FOR DETECTION OF PRETERM LABOR, A LEADING CAUSE OF FETAL MORTALITY AND MORBIDITY. COMMERCIALLY AVAILABLE SENSORS FOR MONITORING INTRAUTERINE CONTRACTIONS USE CUMBERSOME BELTS AND LARGE AND BULKY SENSORS WHICH ARE UNCOMFORATABLE AND LIMIT THE PATIENT'S MOBILITY. A SMALL AND SIMPLE SELF-ADHERING INTRAUTERINE PRESSURE MONITOR HAS BEEN ...

INTRAOPERATIVE AUTOTRANSFUSION SYSTEM (IOAT) ASPIRATES WASTE BLOOD FROM SURGICAL WOUND SITE, PURIFIES AND RETURNS IT TO THE SAME PATIENT. WE DEVELOPED AND EVALUATED IN-VITRO AND IN-VIVO A NEW IOAT SYSTEM WHICH IS DESIGNED TO PURIFY THE ASPIRATED WASTE BLOOD USING HOLLOW FIBER MEMBRANE FILTERS INSTEAD OF USING CENTRIFUGES, AND RETURN THE PURIFIED BLOOD CELLS TO THE PATIENT IN A CLOSED LOOP CONTINUO ...

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