Award Data

The United States produces significant quantities of waste materials that are discarded. These wastes include organic components of municipal solid waste (MSW), biosolids from wastewater treatment plants and agricultural wastes. The release of these materials and their byproducts into the environment can have serious consequences, such as pollution of ground and surface water resources and spread ...

DESCRIPTION provided by applicant Clean water is one of the most basic societal needs in the world Few situations incite more public outcry than when a community learns that their drinking water has been tainted Two of the biggest threats to groundwater quality in the U S are contamination from either chlorinated solvents or petroleum Left unattended the size and scope of the problems asso ...

DESCRIPTION provided by applicant Improving STEM focused curriculum is a primary objective of the current U S administration and is crucial for ensuring that upcoming generations receive the training and skills necessary to compete in the existing global economy To that end there is an urgent need for additional effective teaching tools able to reach a generation that requires instant access ...

DESCRIPTION provided by applicant Pancreatic cancer PaC has a poor prognosis in most cases due to the lack of early detection owing to its nonspecific asymptomatic nature An effective inexpensive screening tool is needed for early diagnosis within years of tumor initiation It is well accepted that genomic instability is a hallmark of cancer Recent research indicates that less than ...

DESCRIPTION provided by applicant The absence of safe effective strategies for the management of ocular pain is motivating the development of a novel topical drug suitable for patient self administration Conventional local anesthetics such as proparacaine inhibit voltage gated Na ion channels and are highly effective for the management of ocular pain in acute in office settings However ...

DESCRIPTION provided by applicant The long term goal of this project is to develop and test a nutritional product that will improve physical function in individuals with heart failure H in the geriatric population Our approach to nutritional therapy NT focuses on increasing skeletal muscle strength improving vascular reactivity and optimizing regulation of energy substrate metabolism All ...

DESCRIPTION provided by applicant The overall goal of this project is to test a meal replacement beverage that will ultimately preserve muscle loss during calorie restriction weight loss CRWL in obese older individuals We previously developed a meal replacement rich with a proprietary blend of essential amino acids TMR that was more than three times as effective as whey protein in stimulat ...

DESCRIPTION provided by applicant Advanced approaches for genetic or epigenetic modification of embryonic stem ES cells including TALEN ZFN or CRISPR catalyzed genetic modifications or modulation of gene expression via small RNAs synthetic mRNAs or recombinant transcription factors have revolutionized our ability to modify the cells from which novel mouse lines are produced In contra ...

DESCRIPTION provided by applicant The purpose of the proposed program is to develop a new noninvasive field deployable method using surface enhanced Raman spectroscopy SERS for detecting and quantifying the metabolites of drugs of abuse in a urine sample a method useful even after a period of several days post use Raman detection of metabolites identifying significant structural groups ...

DESCRIPTION provided by applicant We propose to develop a new type of monitor to directly and simultaneously identify multiple biomarker metabolites in persons suspected of having been exposed to alcohol The technology we plan to utilize is surface enhanced Raman scattering SERS based on a well known inelastic laser light scattering analytical technique for precise lab identification of org ...