Award Data

MOUTHSTICKS OR ORTHODONTIC ORTHOSES ARE WIDELY USED BY PEOPLE WITH SPINAL CHORD INJURIES OR SIMILAR DISABILITIES TO INCREASE CONTROL OVER THEIR ENVIRONMENT. PEOPLE WITH THE ADDITIONAL LIMITATION OF LITTLE OR NO ANTERIOR/POSTERIOR HEAD MOTION MAY BENEFIT FROM AN EXTENDIBLE MOUTHSTICK. HOWEVER, COMMERCIAL EXTENDIBLE MOUTHSTICKS SUFFER IN THAT THEIR ACTION IS OFTEN SLOW, EXTENDIBILITY IS LIMITED, OR ...

The goal is to develop a knowledge-based expert management system to deliver cost-effective quality medical care. This system will allow health care providers to plan and allocate services within the existing budgeting and economic constraints. The methodology consists of 1) building an integrated database of clinical and management information, 2) designing the knowledge representation used in th ...

Development of novel boronated compounds and use of epithermal neutrons has now generated much interest in 10B-boron capture neutron therapy of different tumors. However, no suitable methods exist that allow investigation of their pharmacokinetics in human subjects or in vivo measurement of the ratio of intracellu- lar/extracellular 10B at the time of irradiation. A new approach based on the use o ...

THE RESULT OF THIS PHASE I EFFORT WILL BE A DETAILED PLAN TO SIGNIFICANTLY INCREASE THE SPEED AND, HENCE, THE INTERACTIVITY OF ANALYZE, AN ALREADY USEFUL MEDICAL IMAGE ANALYSIS SYSTEM. ANALYZE IS A SOFTWARE SYSTEM FOR THE ANALYSIS OF MEDICAL IMAGES, DEVELOPED AT MAYO FOUNDATION'S BIOTECHNOLOGY COMPUTER RESOURCE. INCREASED PERFORMANCE WILL BE ACHIEVED BY IMPLEMENTING SELECTED PORTIONS OF ANALYZE ON ...

We will develop a new construction method for receiver coils for magnetic resonance imaging (MRI) of the human breast. These coils will be custom-shaped to individual patients in a quick, economical, and comfortable manner. Since each structure fits the individual patient closely, the coil system permits quantitatively repeatable imaging with accurately reproducible geometry. The structure for sur ...

THIS PHASE II PROJECT WILL DEVELOP TRAINING MATERIALS, INCLUDING A MANUAL, TO ASSIST NATIVE AMERICAN TRIBES, COMMUNITIES AND ORGANIZATIONS IN THEIR COMPREHENSIVE TOURISM DEVELOPMENT PLANNING AND IMPLEMENTATION. FURTHER, THE PROJECT WILL PLAN AND CONDUCT A WORKSHOP, INVOLVING A CROSS SECTION OF NATIVE AMERICAN TRIBES AND ORGANIZATIONS, AS A MEANS OF TESTING AND EVALUATING THE TRAINING AND TECHNICAL ...

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Interactive multimedia materials teaching safer sexual practices will be developed to motivate, educate, and prevent relapse in young heterosexual adults. Target group members will include sexually active, 18 to 29 year old women and men, with and without sexually transmitted diseases, either undergraduate or graduate students, as well as employed or unemployed persons in this age range. Subject r ...

The goal is to publish an assessment battery for normal and disabled children from 2 1/2 to 7 years of age and to make it available to clinicians, educators, and researchers. The battery will incorporate three innovative features that are important for effective assessment of children's cognitive functioning and are not included on any other early childhood assessment battery. These features are 1 ...

Cyclosporin brought the field of transplantation science into the mainstream of medicine. Unfortunately, long-term survival and quality of life for transplant recipients are still severely diminished. Recently, the natural products, FK-506 and rapamycin, have proven in studies to be safe, more potent, and more effective than cyclosporin. Furthermore, these drugs appear to act synergistically possi ...