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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. Expanding Tyto Online: Earth & Space Science Quests & Sandbox for Middle School

    SBC: Immersed Games, Inc.            Topic: 91990018R0006

    In prior research and development, the developers created Tyto Online, an online multiplayer sandbox game where middle school students engage in quests to apply life science learning. This project will extend the game by developing a prototype for the Earth and Space science domain, with a prototype including quests for the Climate and Weather topic aligned to Next Generation Science Standards (NG ...

    SBIR Phase I 2018 Department of EducationInstitute of Education Sciences
  2. Topic 377: Symptom Management and Intervention Roadmaps (STaIRS)

    SBC: Carevive Systems, Inc.            Topic: NCI

    Numerous adverse symptoms are under-detected in cancer care resulting1-3 in missed opportunities for intervention; leading to poor treatment adherence, avoidable hospitalizations, and worse morbidity and survival. The IOM proposed shaking up the current symptom paradigm from reactive to proactive, personalized, technology-enabled models of symptom care as a solution to this clinical quality crisis ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Discovery of new small molecule TLR4 agonists for the treatment of allergic rhinitis

    SBC: INIMMUNE CORP            Topic: NIAID

    The long term goal of this proposal is the development of an intranasal stand alone TLRagonist to treat allergic rhinitisUnlike antigen specific therapythis allergen independent approach will be broadly applicable to a vast array of allergens patients are exposed toSuch treatment would provide relief within hours of administrationproviding short term symptom controland has the potential to deliver ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  4. A novel biomaterial based therapy utilizing auto antigen and adjuvant for the amelioration of Type Diabetes

    SBC: ONEVAX, LLC            Topic: NIAID

    Immune mediated diseases such as type diabetes T D multiple sclerosis rheumatoid arthritis and systemic lupus erythematosis are reaching epidemic proportions in the US T D affects an estimated million Americans with more than new patients diagnosed annually resulting in roughly $ B in health care costs in the US each year T D is an autoimmune disease characterized by effector ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. An interactive App to Promote Safe and Effective use of Opioids in Young Children Postoperatively

    SBC: ARCHIE MD INC.            Topic: NIDA

    In recent years increased attention to pain in children and adolescents has led to a recent fold increase in opioid prescriptions Unsurprisingly the annual rates of analgesic related adverse drug events AR ADEs have soared to include andgt hospital admissions and hundreds of accidental overdose deaths in children and adolescents and has remained a significant problem At the heart of ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Biomaterial based delivery of Interleukin to Regulatory T Cells for the amelioration of Type Diabetes

    SBC: ONEVAX, LLC            Topic: NIAID

    Type Diabetes T D results from a breakdown of self tolerance that is characterized by immune cell mediated destruction of the insulin producing cells in the pancreas Ultimately glucose metabolism is interrupted resulting in the development of life threatening complications such as heart disease and renal failure T D affects an estimated million Americans with more than new patie ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Development of Environmental Health Education Games

    SBC: MEADOWLARK SCIENCE AND EDUCATION, LLC            Topic: NIEHS

    PROJECT SUMMARY Improving STEM focused curriculum is a primary objective of the current U S administration and is crucial for ensuring that upcoming generations receive the training and skills necessary to compete in the existing global economy To that end there is an urgent need for additional effective teaching tools able to reach a generation that requires instant access to information and a ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Insert Earphones with Integrated In Ear Calibration

    SBC: Intelligent Hearing Systems Corp.            Topic: Y

    The specific aim of this project is to develop an insert earphone with integrated in ear sound level calibration capabilities Insert earphones provide great advantages for hearing testing with a convenient and comfortable way to deliver a stimulus with high noise and intra aural attenuation They not surprisingly have become a standard clinical transducer However their exact calibration over a ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Innovation for the earlydetection diagnosis and quantification of diabetic cardiomyopathy

    SBC: AVENTUSOFT L.L.C.            Topic: 200

    PROJECT SUMMARY ABSTRACT This SBIR Phase I project will develop an innovative medical device useful for rapid automated characterization of myocardial performance in diabetes patients Left ventricular systolic and diastolic myocardial impairment is the most common manifestation and the systolic function is monitored with left ventricular ejection fraction measurement and the diastolic function i ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. A computational platform to prioritize drugs and target genes for therapeutic intervention

    SBC: Genetic Networks, LLC            Topic: NCATS

    Project Summary This project proposes implementation of a computational discovery platform that quantifiably identifies and prioritizes both targets and compounds for therapeutic intervention This platform is based on a novel fusion of two state of the art computational approaches phenolog mapping and functional networks with proprietary data from our powerful gene drug screening assays HIP H ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health

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