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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Multispectral Sensor for Chemical Composition Analysis of Ultrafine Aerosols in Air Quality Assessment
SBC: SPECTREE INC. Topic: RProject SummaryWe propose developing and validating a novel platform technology that combines the collection and chemical analysis of ultrafine particles using an in-situ multispectral technique. The sample, collected directly onto the analysis substrate, is analyzed via excitation-emission matrix (EEM) spectroscopy. This approach will be validated against laboratory combustion-generated aerosols, ...
STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
LIGHTSITE IIIB: Clinical Evaluation of Photobiomodulation (PBM) in dry AMD Patients
SBC: LUMITHERA INC Topic: NEIABSTRACT As the population continues to age, degenerative ocular diseases become increasingly common and create tremendous burden on the health care system. Age-related macular degeneration (AMD) is a progressive ocular disease that causes visual impairment and blindness in its most advanced form and is characterized by loss of function and cell death in the macula, a central and critical part of ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Development of a Universal Assay for Minimal Residual Disease in Acute Myeloid Leukemia using Duplex Sequencing
SBC: TWINSTRAND BIOSCIENCES INC Topic: NCIProblem: With a 5-year survival of ~30%, AML is the 6th deadliest cancer, and rt20,000 new patients are diagnosed each year in the United States. Although most patients achieve Complete Remission (CR) with aggressive therapy, most will eventually relapse. The criteria for CR, however, is based on historical diagnostic methods, and patients in CR may carry up to 1010 residual leukemia blasts. Signi ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
AI-based AML risk stratification using next generation cytogenomics
SBC: PHASE GENOMICS, INC. Topic: 394ABSTRACTChromosome aberrations are a hallmark of acute myeloid leukemia and offer mechanistic and prognostic insights into disease. As such, a combination of cytogenetic assays are routinely applied as a part of the AML diagnostic workflow. While offering invaluable information on disease severity, most chromosome aberrations fall into the “cytogenetic abnormalities not classified” or “compl ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Emulsion digital PCR
SBC: Dplexbio Topic: NIAIDProject Summary This proposed project aims to develop a new type of digital PCR platform which eliminates the need for uniform volumes and thereby reduces the complexity, cost, and run time of digital PCR while increasing its dynamic range. The result is a higher performance digital PCR system that matches the simplicity, speed, and low per-assay cost of real-time PCR. Real-time PCR maintains grea ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Significant expansion of spectral multiplexing in PCR
SBC: LAMPROGEN INC Topic: 400Project Summary There have been long-standing discussions about the role of NGS (next-generation sequencing) versus real-time PCR in clinical diagnosis, prognosis, and screening. NGS offers unrivaled discovery power and represents the ultimate in multiplexing capability. NGS, however, is expensive and often requires complex workflows with a long turnaround time. Real-time PCR, in contrast, is comp ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Advanced Contingency Management System for Reduction of Alcohol Use.
SBC: Managed Health Connections LLC Topic: 350Project Summary/Abstract Alcohol abuse remains a significant cause of preventable morbidity and mortality in the US. Yet only 15% of those with AUD receive treatment. Our group, and others have demonstrated that contingency management (CM) is an effective approach for reducing alcohol use in problematic drinkers. This project seeks to demonstrate the capability of an end-to end CM platform designe ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Chromosomal aberration detection in FFPE tissue using proximity ligation sequencing
SBC: PHASE GENOMICS, INC. Topic: NCIABSTRACT The detection of chromosomal aberrations is a frontline diagnostic for the spectrum of blood neoplasms. Chromosomal aberrations, such as translocations, inversions, deletions and insertions, have been historically identified using cytogenetic methods or more recently through application of long read sequencing or optical mapping technologies. These methods have been less applicable in sol ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
An expanded 75-color panel of Pdots for spectral multiplexing
SBC: LAMPROGEN INC Topic: 400Project Summary Flow cytometry is widely used in basic and translational research and in clinical diagnostic assays. Spectral flow cytometry represents a revolutionary change in the approach to flow cytometry by using full spectral information from each fluorophore—by collecting the emission over the full spectrum and using multiple excitation sources for each fluorophore to obtain a spectral ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Booth™ by Opio™: Developing technology to expand the reach of opioid treatment programs into rural and underserved areas.
SBC: Opio Connect, Inc. Topic: NIDAThe goal of this project is to develop a treatment booth with technology that allows opioid treatment programs to remotely dispense, either methadone or buprenorphine, under medical observation through telemedicine to a patient in a treatment booth. We believe that robotic automation is the ideal application to perform the same mechanical functions of the nurse at the dosing window. Specifically, ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health