Award Data

The broader impact/commercial potential of this Small Business Innovation Research Phase I project is opening a new, low-temperature range of Diesel emission control currently unavailable, while providing further flexibility in Diesel vehicle performance significant for commercial vehicles particularly those in stop-and-go operations (city-type duty cycles). Its environmental and societal impacts ...

This Small Business Innovation Research Phase I project will support the development of a confocal optical microscope with two-dimensional topographical profiling and multiple spectroscopic modes in a single, affordable precision instrument. The system will make a major impact in the $6.2 billion microscope market, with a near-term market penetration potential of over 5%, and significant growth po ...

This SBIR Phase I project seeks to develop a novel low-cost molecular filter for use in harsh environments. This is accomplished using commodity silica gel, commonly found as a desiccant in food packing, whose pores can be made to be only a few molecules wide. Accurate tuning of the size and shape of the silica gel pores enables certain molecules to pass through while others are block from passing ...

The broader impact/commercial potential of this Small Business Innovation Research Phase I project includes the development of new methods to biodegrade waste plastics. Plastic waste is an significant environmental burden. Over 300 million tons of plastic are used each year, resulting in millions of tons of persistent plastic waste, some of which can take up to 600 years to degrade. Mealworms (Ten ...

This project will develop an immersive and dynamic multi-player game that addresses a pressing need to provide engaging technologies that prepare students to apply collaborative, cross-disciplinary scientific practices to global societal challenges. In an augmented classroom with their real life peers, students must establish a colony on Mars that is capable of sustaining thousands of refugees fro ...

This Small Business Innovation Research Phase I project will enable video-rate three-dimensional (3D) imaging within two-photon microscopes (TPMs) through the use of an electrostatically actuated deformable membrane mirror (DMM). As a subset of laser scanning microscopes (LSMs), TPMs achieve very high spatial resolution by using a focused, high-power laser beam to excite fluorescence via the simul ...

This NSF SBIR Phase I project takes a unique holistic approach to both tumor imaging and cancer drug delivery. This approach harnesses cancer cell proteins already in the body to allow selective delivery of tumor imaging agents or cancer-killing drugs to, and into, cancer cells. By choosing cancer-specific targeting proteins, the drugs will be transported primarily into cancer cells and undesirabl ...

This SBIR Phase I project will produce an innovative reading application, to support science learning. Although the science textbook is a central curricular resource, this resource is often inaccessible and difficult to read. Science textbooks are syntactically (grammatically) and semantically (word meaning) complex. Specifically, elementary and secondary science texts are often written 3 to 5 yea ...

This SBIR Phase I project aims to develop a superior alternative to the current frontline treatment for children?s Acute Lymphoblastic Leukemia (ALL). The primary treatment option has a host of negative side effects resulting from the use of poly(ethylene glycol) (PEG) conjugated to the L-asparaginase enzyme. Antibodies made against this drug can cause the body to eliminate it rapidly or result in ...

The broad impact of this SBIR Phase I project is in the development of a new cokeless process to melt iron and scrap steel while meeting stringent environmental regulations. The process being investigated will potentially shift the paradigm of difficult pollution control to the use of a clean fuel, such as natural gas. It has the potential to cut down 75% of the greenhouse gas emissions by compari ...