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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Novel approaches to extending glucose sensor lifespan

    SBC: AEGIS BIOSCIENCES, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Long term transcutaneous devices such as catheters; require patients to endure extended skin breaches (wounds) that can be difficult to manage clinically, i.e. infection and inflammation. These complications not only shorten device lifespan, but also compromise patient health. In the case of short-term commercial transcutaneous glucose sensors, FDA has approved ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  2. Pandemic H5N1 vaccine containing recombinant H5 and a synthetic TLR4 agonist, GLA

    SBC: TRIA BIOSCIENCE CORP.            Topic: N/A

    DESCRIPTION (provided by applicant): H5N1 is a highly pathogenic avian influenza virus that can cause severe disease and death in humans. H5N1 is spreading rapidly in bird populations world-wide and there is great concern that this virus will begin to transmit between people and cause a global pandemic catastrophe. Vaccines are the cornerstone strategy for combating avian flu but there are numerou ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  3. Thermally Targeted Delivery of Therapeutic Peptides

    SBC: Thermally Targeted Therapeutics, Incorporated            Topic: N/A

    DESCRIPTION (provided by applicant): Current treatment of solid tumors is limited by normal tissue tolerance, inherent tumor resistance to radiation or chemotherapy, and toxicity from systemic administration of antineoplastic agents. The result is a narrow therapeutic index for most current chemotherapeutic agents. Our long term goal is to overcome these limitations by developing a targeted therap ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  4. Intelligent Microtome Instrumentation

    SBC: BARLOW SCIENTIFIC, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Fluorescent tagging of cells using dyes, fluorescent proteins, and quantum dots forms the basis for many powerful analytical methods in modern biology. Locating these cells within entire animals is necessary to study cell delivery, differentiation and gene expression. The Phase II SBIR research is developing an intelligent microtome to provide the means to loca ...

    SBIR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  5. Online Training in the Fundamentals of Eating Disorders Treatment

    SBC: BEHAVIORAL TECH RESEARCH, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This is a Phase I Small Business Innovation Research (SBIR) grant application to support the development of an innovative, online training program to aid in the dissemination of evidence-based Eating Disorder (ED) treatments (e.g., Cognitive Behavioral Therapy and Interpersonal Psychotherapy for Bulimia Nervosa (BN) and Binge Eating Disorder (BED) . The current ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  6. DBT Skills Training Central

    SBC: BEHAVIORAL TECH RESEARCH, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This is a Phase I Small Business Innovation Research (SBIR) grant application to support the development of an innovative, online training aid for Dialectical Behavior Therapy (DBT) skills providers treating borderline personality disorder and substance dependence (BPD-SUD) individuals. The primary purpose of the eventual product, DBT Skills Central, is to help ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  7. Computer-Based Training in Behavioral Activation Treatment for Depressed Adults

    SBC: BEHAVIORAL TECH RESEARCH, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This is a Phase II Small Business Innovation Research (SBIR) grant application to support the further development of an innovative, online training program to aid in the dissemination of Behavioral Activation (BA), a therapy for depression. The current application represents a continued cooperative partnership between the small business, Behavioral Tech Researc ...

    SBIR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  8. Online Training in the Principles and Procedures of Exposure Therapies

    SBC: BEHAVIORAL TECH RESEARCH, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This is a Phase II Small Business Innovation Research (SBIR) grant application to support the further development of an innovative, online training program to aid in the dissemination of exposure therapies (ETs) for anxiety disorders. ETs have consistently and robustly been found effective in the treatment of anxiety disorders. However, these evidence-based tre ...

    SBIR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  9. Utilizing Mobile Technology for DBT Skills Generalization with BPD-SUD Clients

    SBC: BEHAVIORAL TECH RESEARCH, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Substance use disorders (SUD) co-occurring with borderline personality disorder (BPD) pose serious and complex public health problems. Dialectical Behavior Therapy for Substance Abusers (DBT) is an efficacious psychosocial treatment for substance dependent individuals with BPD (Linehan, 1993a, b; Lynch et al., 2007). This is a Phase I Small Business Innovation ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  10. Multifunctional Carriers for Systemic siRNA Delivery

    SBC: SURFAGEN, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The objectives of this research project are to design and develop safe and efficient multifunctional delivery systems for systemic and target-specific delivery of small interfering RNA (siRNA) to treat human diseases with RNA interference (RNAi). RNAi is a natural mechanism for gene silencing and has a great potential to treat human disease by turning off speci ...

    STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
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