Award Data

PROJECT SUMMARY This program aims to develop a novel non opioid therapeutic for the treatment of pain that targets a subtype of the human voltage gated Na ion channel NaV Preliminary data indicate that SiteOneandapos s lead drug candidates may be more effective than opioids for treating certain types of pain and lack the side effects associated with opioid analgesics which include nausea ...

The CRISSP Phase II effort will mature to TRL-6 recyclable launch packaging materials to enable sustainable in-space manufacturing on the ISS and future manned deep space missions. Our Phase I effort began by testing the recycling of current launch packaging materials, identifying several that are possible to recycle. We then prototyped concepts for sealable bags made with readily recyclable A.M ...

The overall goal of this Phase II SBIR effort is to develop a three-wavelength, backscatter transceiver for in situ validation of ongoing High Spectral Resolution Lidar measurements. The key innovation in the effort is the use of a multi-element, non-linear waveguide for highly efficient, three wavelength generation in a collinear geometry ideally suited for use in the backscatter nephelometer at ...

Particle size distribution (PSD) is a fundamental environmental measurement, with diverse biogeochemical applications including carbon cycle science, ecosystem and fisheries modeling, and harmful algal bloom (HAB) detection/prediction. There is optimism that estimates of PSD will be available from ocean color measurements (such as NASA's upcoming PACE mission), and will be able to help constrain g ...

The broader impact/commercial potential of this project results from the advancement of telerobotic control technology for subsea operations. As humans deploy and maintain ever more complex underwater hardware, conduct subsea scientific sampling and exploration and develop natural resources in hostile, deep and remote locations, the need for ROVs (Remotely Operated Vehicles) is increasing. ROVs ha ...

This Small Business Innovation Research Phase II project aims to continue the development of a family of new nanostructured conductive additives for use in high-performance coatings and composite resins. Static charge buildup from the environment is a critical problem in a number of vehicular applications, which increasingly utilize lightweight components constructed from non-conductive plastic or ...

The purpose of our Phase II effort is to help surface actionable and quantifiable data from the text-heavy documents and files currently used by program management office staff, to expose that data in a machine-readable format that maintains a persistent anchor to the text from which it came, and to allow that staff to make faster and better informed decisions based on that data in light of their ...

In the proposed program, Systima Technologies Inc. will develop a tunable ETIVS thermal trigger system for integration into Navy weapon system platforms. The ETIVS trigger technology leverages Systimas existing thermal sensing technology and expertise in design of devices for IM mitigation of solid rocket motors. Benefits of Systimas ETIVS device include passive operation (no power required) until ...

TBD

DESCRIPTIONprovided by applicantThe primary goal of this proposal is to develop and finalize configuration of a rapid molecular diagnostics test to predict antibiotic resistance of th major human uropathogensEscherichia coliKlebsiella pneumoniaeEnterobacter spp and Pmirabilisby determining the sub species clonal identityclonotypeof the infecting bacteria directly from urine samplesCurrentlythe emp ...