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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Improving the Transfer of ERK siRNA Constructs Using Nanoporous Silica

    SBC: APOLLO SRI, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Our research is focused on the potential of acid-prepared mesoporous silica (APMS) as a delivery agent for siRNA constructs to inhibit the ERK1/2 and ERK5 pathways in the treatment of human malignant mesothelioma (MM). These pathways are critical to MM cell proliferation and chemoresistance. Our initial research suggests that APMS will be significantly more eff ...

    STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  2. Head orientation sensing system

    SBC: APPAREO SYSTEMS LLC            Topic: AF071020

    Appareo Systems, LLC, proposes to develop a functional prototype head-mounted position and orientation system (HPOS). The HPOS will be capable of operating in electromagnetic fields of up to 200 volts/meter and will provide at least one degree of accuracy and at least one degree of resolution at a 60 Hz update rate while providing 3 degree of freedom (DOF) information on head orientation, includi ...

    SBIR Phase I 2007 Department of DefenseAir Force
  3. A Global Test of Hemostatic Risk

    SBC: Haematologic Technologies, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Phase I funding for this project supported successful studies that were aimed at demonstrating the feasibility of developing an easy to use, global test in the arena of clinical hemostasis that would be sensitive to antithrombotic drugs, bleeding disorders and thrombotic pathologies. This test comprises a measurement of the rate of thrombin generation and/or to ...

    STTR Phase II 2007 Department of Health and Human ServicesNational Institutes of Health
  4. High Precision Bioassay Using Robotics and Statistics

    SBC: PRECISION BIOASSAY Inc            Topic: N/A

    DESCRIPTION (provided by applicant): Abstract Cell culture bioassays are often laborious and imprecise even after substantial development efforts. These bioassays are used broadly in the biotechnology industry to measure protein or vaccine products in development and for lot release. Imprecise assays and slow assay development contribute to slow product development. Common practice in cell culture ...

    SBIR Phase II 2007 Department of Health and Human ServicesNational Institutes of Health
  5. Theory of Mind Software for Autism and other Communication Disorders

    SBC: LAUREATE LEARNING SYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Full participation in the human social milieu requires that one be able to understand that other people have their own goals, intentions, and beliefs (which may or may not be correct) - and that these epistemic states govern people's behavior. This form of awareness has been called Theory of Mind (ToM). Unfortunately, the development of ToM is severely delayed ...

    SBIR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  6. 3D Virtual Slide System for Creation and Analysis of Focusable Digital Slides

    SBC: MICROBRIGHTFIELD, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Rigorous quantification methods of histological specimens have become a keystone in modern neuroscience such as investigations of neurogenesis, stem cell research, neurotransplantation, neurotoxicology, and the pathogenesis of neurodegenerative and neuropsychiatric diseases. Methods in current practice are not conducive to high-throughput studies because they a ...

    SBIR Phase II 2007 Department of Health and Human ServicesNational Institutes of Health
  7. Integrated Teleconferencing Unit For Home-Based Interactive Exercise For Elders

    SBC: MICRODESIGN CONSULTING, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Supervised group exercise has been shown to be an effective component for improving balance and preventing falls among elders who have suffered falls or exhibit a fear of falling due to frailty. In a Phase I SBIR study, we developed a model for conducting group exercise programs for elders in their homes via video- conferencing, called tele-based group exercise ...

    SBIR Phase II 2007 Department of Health and Human ServicesNational Institutes of Health
  8. High Energy Density, Low-Cost, High Temperature Capacitors for Hybrid Vehicles

    SBC: Sbe Inc            Topic: 05

    Hybrid Electric Vehicles (HEVs) and plug-in Hybrid Vehicles (PHEVs) require advanced technology capacitors, which must have low cost and the ability to operate at 150oC. However, current 150oC film capacitor solutions are expensive and have lower energy density compared to materials that operate at lower temperatures. Polypropylene Film Capacitors represent a potentially cost effective solution ...

    SBIR Phase I 2007 Department of Energy
  9. Automated Connective Tissue Torque Sensor

    SBC: STROMATEC, INC            Topic: N/A

    DESCRIPTION (provided by applicant): The long term goal of this project is to establish the usefulness of needle torque measurements for the diagnosis and monitoring of connective tissue pathology associated with chronic musculoskeletal conditions treated by manual therapies. This project will combine technologies developed in our previous research and technological transfer programs which 1) show ...

    SBIR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  10. A New High-Resolution Method for the Characterization of Heterogeneous Subsurface Environments: Providing Flow and Transport Parameters via the Integration of MultiScale HydroGeophysical Data

    SBC: NEW ENGLAND RESEARCH, INC.            Topic: 49

    Historically, remediation efforts at DOE contaminated sites have relied on numerical models to integrate laboratory and field characterization data, predict the fate and transport behavior of contaminant plumes, design remediation protocols to mitigate contaminant migration, and analyze data from field remediation results. Of particular concern is the effect of subsurface heterogeneities and thei ...

    SBIR Phase I 2007 Department of Energy
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