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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. System for multidimensional analysis of growth and migration of neurons and neuro

    SBC: MICROBRIGHTFIELD, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): We propose the Orion workstation, an innovative, next generation microscope system that provides analysis tools for fully-automated quantitative change analysis in neurite outgrowth dynamics and neuronal precursor migration. The algorithms that will form the basis of this software provide information about changes seen in individual neurites and cells, yielding ...

    SBIR Phase I 2009 Department of Health and Human Services
  2. Children's Computer Assessment of Pain and Mood

    SBC: PSYCHOLOGICAL APPLICATIONS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Ongoing concerns about the management and treatment of children's pain/mood make quantitative assessment in children a high medical priority. Currently, the dominant clinical technique has children indicate only their pain by selecting from among a set of static, stylized facial expressions. Although the widespread use of such methods has yielded substantial cl ...

    SBIR Phase II 2009 Department of Health and Human Services
  3. Three-Dimensional Pain Mapping

    SBC: PSYCHOLOGICAL APPLICATIONS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The objective of this Phase I proposal is to evaluate a new pain assessment method referred to as Three- Dimensional Pain Mapping. Patients use a computer method to indicate the location, intensity and depth of their pain on a model of the human body. The model can be rotated by the patient in order to obtain the most advantageous viewpoints for marking pain. A ...

    SBIR Phase I 2009 Department of Health and Human Services
  4. Development of a Self-Adaptive Air Turbine for Wave Energy Conversion using an Oscillaating Water Column (OWC) Air System

    SBC: Concepts NREC, LLC            Topic: 19a

    The oscillating water column (OWC) is a candidate technology for the economical recovery of the projected 17.5 x 1012 kW-hr energy that is available from the world¿s oceans. While the relative dynamics between the OWC system and the incident water waves are mathematically understood, computational solutions have not been used to ¿tune¿ the OWC turbine-generator sub-systems to operate where the ...

    STTR Phase I 2009 Department of Energy
  5. Development of High-Efficiency Power Amplifiers for 704 MHz

    SBC: Green Mountain Radio Research Company            Topic: 46b

    Accelerators used for nuclear-physics research require megawatts of radio-frequency energy. These accelerators currently employ vacuum-tube power amplifiers or conventional solid-state amplifiers that are inefficient and therefore consume a great deal of prime power. This project will review available transistors, analyze high-efficiency power-amplifier techniques, and experimentally evaluate ca ...

    SBIR Phase I 2009 Department of Energy
  6. Development of High-Efficiency Power Amplifiers for 50- 350 MHz

    SBC: Green Mountain Radio Research Company            Topic: 46b

    Accelerators used for nuclear-physics research require megawatts of radio-frequency energy. These accelerators currently employ vacuum-tube power amplifiers or conventional solid-state amplifiers that are inefficient and therefore consume a great deal of prime power. This project will review available transistors, analyze high-efficiency power-amplifier techniques, and experimentally evaluate ca ...

    SBIR Phase I 2009 Department of Energy
  7. Development of High-Efficiency Power Amplifiers for 350- 500 MHz

    SBC: Green Mountain Radio Research Company            Topic: 02a

    Accelerators used for nuclear physics research require megawatts of radio-frequency energy. These accelerators currently employ vacuum-tube power amplifiers or conventional solid-state amplifiers that are inefficient and therefore consume a great deal of prime power. This project will involve a review of available transistors, an analysis of high-efficiency power-amplifier techniques, and an exp ...

    SBIR Phase I 2009 Department of Energy
  8. Geophysical Monitoring of Multiple Phase Saturation of Rocks: Applications to CO2 Sequestration

    SBC: New England Research, Inc.            Topic: 25c

    The world is increasingly concerned about global warming from the greenhouse effect, and the voluminous CO2 emissions from human activities are a significant contributor to this problem. Carbon sequestration is the concept of isolating and removing CO2 gases from large point sources and then holding them in secure storage. To be viable, any CO2 sequestration option must be safe, predictable, rel ...

    SBIR Phase I 2009 Department of Energy
  9. Improving the Transfer of ERK siRNA Constructs Using Nanoporous Silica

    SBC: APOLLO SRI, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Our research is focused on the potential of acid-prepared mesoporous silica (APMS) as a delivery agent for siRNA constructs to inhibit the ERK1/2 and ERK5 pathways in the treatment of human malignant mesothelioma (MM). These pathways are critical to MM cell proliferation and chemoresistance. Our initial research suggests that APMS will be significantly more eff ...

    STTR Phase I 2007 Department of Health and Human Services
  10. A Global Test of Hemostatic Risk

    SBC: Haematologic Technologies, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Phase I funding for this project supported successful studies that were aimed at demonstrating the feasibility of developing an easy to use, global test in the arena of clinical hemostasis that would be sensitive to antithrombotic drugs, bleeding disorders and thrombotic pathologies. This test comprises a measurement of the rate of thrombin generation and/or to ...

    STTR Phase II 2007 Department of Health and Human Services

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