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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Therapeutic factor XI blockade for sepsis

    SBC: Aronora, Inc            Topic: NIAID

    DESCRIPTION (provided by applicant): This SBIR Phase II grant will support the commercial development of an injectable biological product candidate, a unique proprietary recombinant humanized anti-factor XI monoclonal antibody (AXIMAB), towards an investigational new drug (IND) application. The lead indication for AXIMAB is severe bacterial sepsis, which is a major cause of mortality in hospitaliz ...

    SBIR Phase II 2012 Department of Health and Human Services
  2. Connective Tissue Motion Measure 2

    SBC: STROMATEC, INC            Topic: NCCAM

    DESCRIPTION (provided by applicant): Connective tissue dysfunction is emerging as a potentially important, and so far mostly overlooked, factor in the pathophysiology of chronic low back pain (LBP). We have developed and tested a novel instrument (StromaGlide) and test (Connective Tissue Motion Measure - CTMM) -quantifying the functional behavior of perimuscular connective tissues. The results of ...

    SBIR Phase II 2012 Department of Health and Human Services
  3. Online Training for Resource Parents of Substance-Exposed Children

    SBC: NORTHWEST MEDIA, INC            Topic: NIDA

    DESCRIPTION (provided by applicant): While foster-adoptive parents receive some rudimentary training just prior to or in the early months following adoption finalization, many stil harbor unrealistic expectations about adoption and are unaware of the severe behavioral problems they may encounter, no less the role that exposure to substance abuse may play in the child's development. Our Phase ...

    SBIR Phase II 2012 Department of Health and Human Services
  4. SUBSTANCE ADDICTION COLLABORATION CHANNEL(SACC)

    SBC: Health Education Research Systems, llc            Topic: NIDA

    DESCRIPTION (provided by applicant): (Phase-2, Renewal) The SACC-Substance Addiction Collaboration Channel(R) platform is a new Collaboration, WEB-2.0 springboard specifically designed to structure and share information across the Behavioral/Mental Health Workforce community with the special focus on Substance-Addiction Disorders. SACC is an individual and group-level application platform th ...

    SBIR Phase II 2012 Department of Health and Human Services
  5. Software to Enrich the Noun Lexicons and Lexical Learning of Children with Autism

    SBC: LAUREATE LEARNING SYSTEMS, INC.            Topic: NIDCD

    DESCRIPTION (provided by applicant): The objective of this project is to develop and field-test prototype software for a research-based vocabulary development program featuring a combined lexical-cognitive approach to noun acquisition. The target population for the curriculum will be 3-8 year old children with Autism Spectrum Disorders (ASD), as well as a broad range of other children with languag ...

    SBIR Phase II 2012 Department of Health and Human Services
  6. Phase 2 REAL-TIME MONITORING OF TRACE AMOUNTS OF PESTICIDES IN WATER AND FOOD USI

    SBC: DAHL NATURAL L.L.C.            Topic: NIEHS

    DESCRIPTION (provided by applicant): Development of a phase 2 beta for demonstration in Tree Top juice processing plant of a Field Applicable Real-time Remote Monitoring Sensor Device capable of detecting multiple pesticides simultaneously in unfiltered juice, fluid or waste water. We propose to further develop the carbon nanotube matrices active biosensor area for effective immobilization of mult ...

    SBIR Phase II 2012 Department of Health and Human Services
  7. Embosser Using Polymer Roller for Production of Improved Braille and Tactile Grap

    SBC: VIEW PLUS TECHNOLOGIES INC            Topic: NEI

    DESCRIPTION (provided by applicant): The specific aim of this proposal is to develop and implement a new type of technology for production of braille and tactile graphics that uses a system in which metal punch pins fire into a smooth polymer-coated shaftrather than into a machined metal die as with most current embossing technologies. The successful completion of this project will yield a new bra ...

    SBIR Phase II 2012 Department of Health and Human Services
  8. Factor XI inhibitor for thrombosis

    SBC: Aronora, Inc            Topic: NHLBI

    DESCRIPTION (provided by applicant): Thrombotic cardiovascular diseases including venous thromboembolism (VTE), deep vein thrombosis (DVT), myocardial infarction, and ischemic stroke, remain leading causes of death and disability in the U.S. Although effective antithrombotic agents are available, these drugs inadvertently target vital hemostatic molecular mechanisms and can produce severe dose-lim ...

    SBIR Phase II 2012 Department of Health and Human Services
  9. System for multidimensional analysis of growth and migration of neurons and neuro

    SBC: MICROBRIGHTFIELD, INC.            Topic: NIMH

    DESCRIPTION (provided by applicant): This project aims at developing the Orion microscope system, a highly innovative combined software/hardware product, which will facilitate automated investigations of dynamics of migration of neuronal precursors and neurite outgrowth in vitro using time-lapse video-microscopy (TLVM). To achieve this goal, the Orion microscope system will combine novel software ...

    SBIR Phase II 2012 Department of Health and Human Services
  10. Mission Reconnect: Promoting Resilience and Reintegration of Post-Deployment Vete

    SBC: Collinge And Associates, Inc.            Topic: NIMH

    DESCRIPTION (provided by applicant): There is an urgent and growing need for mental health interventions supporting both short- and long-term reintegration of veterans of OIF and OEF into their communities and significant relationships. Innovative approaches are needed to support the well-being of veterans who may not access or be reached by formal services. Objectives. This Phase II project will ...

    SBIR Phase II 2012 Department of Health and Human Services

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