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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Bioartificial Brain Slices for Drug Screening

    SBC: MICROBRIGHTFIELD, INC.            Topic: NIMH

    DESCRIPTION (provided by applicant): It has become evident that the microvasculature (i.e., the vasculature visible at the light microscopic level) plays a critical role in the plasticity of he brain under various physiological and pathological conditions,including fundamental processes in neuroplasticity such as axonal, dendritic and synaptic plasticity during brain development, learning, recover ...

    SBIR Phase I 2013 Department of Health and Human Services
  2. Automated 3D quantitative analysis of dendritic spines imaged with light microsco

    SBC: MICROBRIGHTFIELD, INC.            Topic: NIMH

    DESCRIPTION provided by applicant In this Lab to Marketplace proposal we aim to develop the MBF SpineStudio software incorporating the innovative laboratory based NeuronStudio software created at the Mount Sinai School of Medicine Our SpineStudio software will enable automated detection reconstruction and morphological classification of the structural analysis of dendritic spines By creating this ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  3. PRISMS- Profile Resolving In-Situ Soil Moisture Sensor

    SBC: Transcend Engineering and Technology, LLC            Topic: 20a

    Many contaminated DOE sites are located in arid regions where depth to groundwater is significant and/or contaminants were discharged into a vadose zone through which transport to the groundwater table is dominated by unsteady, unsaturated groundwater flow. The absence of an effective means to monitor vadose zone moisture content in profile has been a persistent impediment to developing and calibr ...

    SBIR Phase I 2013 Department of Energy
  4. Variable Inlet Bypass for Efficient Wide Flow Range Turbocharger Compressor

    SBC: Concepts NREC, LLC            Topic: 06c

    Increased use of Exhaust Gas Recirculation (EGR) combined with engine downsizing has pushed automotive turbocharger compressor operation towards and often beyond its efficient and stable operating boundaries. Much of the drive cycle is spent operating the compressor at low flow rates and low pressure ratios, near the compressor surge line, in an area which is usually of low efficiency. Our prelimi ...

    SBIR Phase I 2013 Department of Energy
  5. Connective Tissue Motion Measure 2

    SBC: STROMATEC, INC            Topic: NCCAM

    DESCRIPTION (provided by applicant): Connective tissue dysfunction is emerging as a potentially important, and so far mostly overlooked, factor in the pathophysiology of chronic low back pain (LBP). We have developed and tested a novel instrument (StromaGlide) and test (Connective Tissue Motion Measure - CTMM) -quantifying the functional behavior of perimuscular connective tissues. The results of ...

    SBIR Phase II 2012 Department of Health and Human Services
  6. Software to Enrich the Noun Lexicons and Lexical Learning of Children with Autism

    SBC: LAUREATE LEARNING SYSTEMS, INC.            Topic: NIDCD

    DESCRIPTION (provided by applicant): The objective of this project is to develop and field-test prototype software for a research-based vocabulary development program featuring a combined lexical-cognitive approach to noun acquisition. The target population for the curriculum will be 3-8 year old children with Autism Spectrum Disorders (ASD), as well as a broad range of other children with languag ...

    SBIR Phase II 2012 Department of Health and Human Services
  7. System for multidimensional analysis of growth and migration of neurons and neuro

    SBC: MICROBRIGHTFIELD, INC.            Topic: NIMH

    DESCRIPTION (provided by applicant): This project aims at developing the Orion microscope system, a highly innovative combined software/hardware product, which will facilitate automated investigations of dynamics of migration of neuronal precursors and neurite outgrowth in vitro using time-lapse video-microscopy (TLVM). To achieve this goal, the Orion microscope system will combine novel software ...

    SBIR Phase II 2012 Department of Health and Human Services
  8. scribIT: a System for Freehand Production, Editing, Communication and Reproductio

    SBC: E.A.S.Y. LLC            Topic: NCATS

    DESCRIPTION (provided by applicant): The ultimate goal of this project is to market a electromechanical and software system for Blind and Low Vision (B/LV) individuals that will enable creation, communication and reproduction of freehand drawings. In school, at home and in the workplace, virtually everyone needs to be able to produce a wide variety of freehand sketches, diagrams, driving direction ...

    STTR Phase I 2012 Department of Health and Human Services
  9. Microscope Based Brain Positioning System for Anatomical Navigation

    SBC: MICROBRIGHTFIELD, INC.            Topic: NIMH

    DESCRIPTION (provided by applicant): Neuromorphologic analyses at the light microscopic level have significantly contributed to our understanding of the function and pathology of the brain. We propose to develop an integrated commercial product for providing automatic, immediate feedback about the neuroanatomic borders and name of a brain region that is currently being inspected under a light micr ...

    SBIR Phase I 2012 Department of Health and Human Services
  10. Multi-Suture Delivery Device for Bioabsorbable Fasteners

    SBC: OPUS KSD, INC.            Topic: NCATS

    DESCRIPTION (provided by applicant): The goal of this project is to develop a multi-suture delivery device capable of inserting bioabsorbable fasteners, with improved cost/performance over all other skin closure methods, and demonstrate safety and efficacyin animal trials. Traditional stitches and metal staples penetrate through the skin, restrict the patient from bathing and must be removed, some ...

    SBIR Phase I 2012 Department of Health and Human Services

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