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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. THE PURPOSE OF THIS GRANT IS TO SELECT APPROVABLE DRUGS FOR THE TREATMENT OF FOUR ORPHAN DISEASES: SICKLE CELL DISEASE,THALASSEMIA, HEMOCHROMATOSIS, AND ERYTHROPOIETIC PORPHYRIAS.

    SBC: Atmospheric Health Sciences            Topic: N/A

    THE PURPOSE OF THIS GRANT IS TO SELECT APPROVABLE DRUGS FOR THE TREATMENT OF FOUR ORPHAN DISEASES: SICKLE CELL DISEASE,THALASSEMIA, HEMOCHROMATOSIS, AND ERYTHROPOIETIC PORPHYRIAS.FROM THE AVAILABLE WORLD MEDICAL LITERATURE ON THE FOUR DISEASES, DRUGS THAT ARE CLAIMED TO BE EFFECTIVE WILL BE EVALUATED AND CATEGORIZED AS TO THE EXTENT OF CLINICAL TESTING AND ANIMAL EXPERIMENTATION. THE THERAPEUTIC R ...

    SBIR Phase I 1983 Department of Health and Human Services
  2. RESEARCH ON AN AUDITORY "MOBILE" FOR INFANT

    SBC: Babeco            Topic: N/A

    N/A

    SBIR Phase I 1983 Department of Health and Human Services
  3. IMPLANTABLE ANASTOMOSIS POTENCY MONITOR

    SBC: Biomedics Inc            Topic: N/A

    N/A

    SBIR Phase I 1983 Department of Health and Human Services
  4. COST EFFECTIVE NON-INVASIVE BLADDER VOLUME INSTRUMENT

    SBC: Biomedics Inc            Topic: N/A

    N/A

    SBIR Phase I 1983 Department of Health and Human Services
  5. THE OBJECTIVE OF THIS PROJECT IS THE DEVELOPMENT OF A SMALL,PRE-PACKAGED DISPOSABLE ASSAY KIT FOR THE DETERMINATION OF CARBOXYHEMOGLOBIN (COHG) LEVELS IN BLOOD OF PATIENTS SUSPECTED OF CARBON MONOXIDE INTOXICATION (COI).

    SBC: Common Sensing Inc            Topic: N/A

    THE OBJECTIVE OF THIS PROJECT IS THE DEVELOPMENT OF A SMALL,PRE-PACKAGED DISPOSABLE ASSAY KIT FOR THE DETERMINATION OF CARBOXYHEMOGLOBIN (COHG) LEVELS IN BLOOD OF PATIENTS SUSPECTED OF CARBON MONOXIDE INTOXICATION (COI). CARBON MONOXIDE, ONE OF THE MOST COMMON AND DEADLY GASEOUS POLLUTANTS ASSOCIATED WITH OUR WAY OF LIFE, IS RESPONSIBLE FOR A LARGE NUMBER OF FATALITIES AND INCAPACITATING MORBIDITI ...

    SBIR Phase I 1983 Department of Health and Human Services
  6. ADENOSINE DEAMINASE (ADA) AND PURINE NUCLEOSIDE PHOSPHORYLASE (PNP) DEFICIENCIES ARE ASSOCIATED WITH CERTAINIMMUNODEFICIENCIES IN HUMANS.

    SBC: Ert            Topic: N/A

    ADENOSINE DEAMINASE (ADA) AND PURINE NUCLEOSIDE PHOSPHORYLASE (PNP) DEFICIENCIES ARE ASSOCIATED WITH CERTAINIMMUNODEFICIENCIES IN HUMANS. ENZON WILL USE PATENTED METHODOLOGY TO PREPARE THERAPEUTIC MODIFICATIONS OF ADA AND PNP. THE PROCEDURE CONSISTS OF ATTACHMENT OF MONOMETHOXYPOLYETHYLENE GLYCOL (PEG) IN SUFFICIENT AMOUNTS TO ENZYMES TO PRODUCE CONJUGATES THAT ARE ESSENTIALLY NONIMMUNOGENIC AND S ...

    SBIR Phase I 1983 Department of Health and Human Services
  7. THIS PROPOSAL IS DIRECTED TOWARD DEVELOPING A RAPID DIRECT METHOD FOR DETECTING MUTATIONS IN BLOOD CELLS PROVIDING A POSSIBLE ASSAY FOR THE SCREENING OF LARGE NUMBERS OF INDIVIDUALS.

    SBC: Genetic Systems Corp            Topic: N/A

    THIS PROPOSAL IS DIRECTED TOWARD DEVELOPING A RAPID DIRECT METHOD FOR DETECTING MUTATIONS IN BLOOD CELLS PROVIDING A POSSIBLE ASSAY FOR THE SCREENING OF LARGE NUMBERS OF INDIVIDUALS. THE ASSAY IS BASED ON ENUMERATING CELLS BEARING MUTANT HLA MEMBRANE ANTIGENS AMONG PERIPHERAL BLOOD LYMPHOCYTES. THE MUTATIONS WILL BE DETECTED BY A NOVEL SEROLOGICAL TEST WHICH YIELDS A POSITIVE SIGNAL BY USE OF TWO ...

    SBIR Phase I 1983 Department of Health and Human Services
  8. OF DIAGNOSING AND MONITORING ATHEROSCLEROSIS.

    SBC: Genetic Systems Corp            Topic: N/A

    OF DIAGNOSING AND MONITORING ATHEROSCLEROSIS. THIS WILL BE BASED ON A METHOD INCORPORATING BLOOD CLEARANCE OF RADIOLABELD ANTIBODIES DIRECTED AGAINST SPECIFIC CONSTITUENTS OF ATHEROSCLEROTIC PLAQUE. FOR THIS PURPOSE, THEY WILL PREPARE A PANEL OF MONOCLONAL ANTIBODIES AGAINST DIFFERENT COMPONENTS OF THE ATHEROSCLEROTIC PLAQUE. ANTIBODIES AGAINST PLAQUE-SPECIFIC OR PLAQUE-ASSOCIATED MARKERS WILL BE ...

    SBIR Phase I 1983 Department of Health and Human Services
  9. IMMUNE COMPLEXES (IC) PLAY AN IMPORTANT ROLE IN THE PATHOGENESIS OF CERTAIN HUMAN DISEASES, SUCH AS SERUM SICKNESS, GLOMERULONEPHITIDES, AND LUPUS ERYTHEMATOSUS, AND ARE ALSO ASSOCIATED WITH RHEUMATOID ARTHRITIS AND A VARIETY OF VASCULITIDES.

    SBC: Genetics Systems Corpon            Topic: N/A

    IMMUNE COMPLEXES (IC) PLAY AN IMPORTANT ROLE IN THE PATHOGENESIS OF CERTAIN HUMAN DISEASES, SUCH AS SERUM SICKNESS, GLOMERULONEPHITIDES, AND LUPUS ERYTHEMATOSUS, AND ARE ALSO ASSOCIATED WITH RHEUMATOID ARTHRITIS AND A VARIETY OF VASCULITIDES. PRESENT TESTS FOR THE DETECTION OF IC RELYON PHYSIOCHEMICAL METHODS OR BIOLOGICALLY BASED ASSAYS WHICHSEPARATE IC FROM FREE ANTIBODY (AB). THE VARIOUS TESTS ...

    SBIR Phase I 1983 Department of Health and Human Services
  10. THIS PROPOSAL IS FOR EXTENDING STUDIES RELATED TO THE EVALUATION OF POLYCATION HEXADIMETHRINE (HDM) AND ITS COMPONENTS AS ANTICANCER AGENTS.

    SBC: Immunogenics Corpon            Topic: N/A

    THIS PROPOSAL IS FOR EXTENDING STUDIES RELATED TO THE EVALUATION OF POLYCATION HEXADIMETHRINE (HDM) AND ITS COMPONENTS AS ANTICANCER AGENTS. THESE INVESTIGATORS HAVE DEMONSTRATED A DIFFERENTIAL EFFECT OF HDM ON MIXED LYMPHOCYTE CELL CULTURE (MLC) AND ON L1210 CELLS. AT THE DOSES WHICH INHIBIT (3)H-THYMIDINE INCORPORATION INTO L1210 CELLS BY 50 PERCENT, THE RESPONSE OF THE MLC WAS STIMULATED TWO-FO ...

    SBIR Phase I 1983 Department of Health and Human Services
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