Award Data

We will evaluate a novel warming method, developed by our collaborator John Bischof, that promises solution of one of the remaining barriers for banking of large organs and vascularized composite tissues. The method involves radiofrequency and magnetic nanoparticles to obtain rapid uniform electromagnetic rewarming of biological materials instead of warming from the outer boundary using convection ...

The long term goal of the proposed research is to develop improved methods for cryopreservation of complex tissues at extreme low temperature. An innovative approach is taken in the proposed line of research, where synthetic ice modulators (SIMs) are combined with established cryoprotective agent (CPA) cocktails to create more favorable conditions for cryopreservation in a process known as vitrifi ...

ABSTRACT:Systima Technologies, Inc. proposes the development of an unmanned hypersonic test vehicle recovery system that will greatly enhance the effectiveness of hypersonic flight testing.Systima plans to perform a comprehensive review of the various hypersonic vehicle test environments and recovery requirements in order to develop recommendations for suitable vehicle recovery technologies for th ...

The operational envelope of hypersonic projectiles and missiles is expanding to higher speeds and more sophisticated RF guidance systems.With this additional operational regime the need for low cost, high temperature materials, such as ceramics is becoming more important.Engineered ceramics manufacturing is a difficult process with frequent instances of flaws which are fatal for ceramic components ...

DESCRIPTION provided by applicant The blood brain barrier BBB is a tight barrier formed by microvessels and capillaries that control the passage of nutrients fluids metabolic products and drugs between the blood and the brain Impaired function of the BBB is involved in a number of major pathologies afflicting the brain such as Alzheimerandapos s disease multiple sclerosis Parkinsonanda ...

DESCRIPTION provided by applicant The non portable BrightArm Duo prototype is being studied SBIR Phase II grant to Bright Cloud International BCI for Upper Extremity UE motor and cognitive maintenance therapy on CVD survivors who are residents of skilled nursing facilities SNF They train using BCI virtual reality VR bimanual games supervised by an Occupational Therapist The vast ma ...

DESCRIPTION provided by applicant Our goal is to develop a novel peptide therapeutic to alleviate brain and vascular injury after hemorrhagic and ischemic stroke Vascular injury is a leading cause of death in the United States with approximately Americans suffering stroke with deaths each year Those who survive are frequently disabled resulting in over one million US st ...

DESCRIPTION provided by applicant With regard to Personal Protective Eyewear PPE technologies a major occupational hazard in high risk industrial sectors such as manufacturing mining construction and warehousing but one which has received very limited attention to date is that associated with the worker transitioning from very bright to dark areas fogging of protective eyewear exacerbat ...

ABSTRACT:A new algorithm, the Daylight Object Restoration Algorithm (DORA), has been developed. DORA includes a novel implementation of the multi-frame blind deconvolution image restoration concept which recovers high-quality object estimates from sequences of degraded images. DORA removes the effects of atmospheric aberration in images recorded at ground-based telescopes, and is designed to opera ...

In response to the Navy need for an uncooled optical transmitter operating at a wavelength near 1 micrometer, Applied Optronics (AO) proposes to develop a GaAs-based Uncooled Integrated Compact Analog Transmitter (UNICAT), comprised of the following integrated components: a frequency-stabilized high-power laser, an integrated high-speed modulator, and power optical amplifier. By using GaAs platfor ...