Award Data

DESCRIPTION (provided by applicant): This project proposes to build and test a 20 L capacity Remediator for medical wastes. Infectious Medical Wastes (IMW), mainly from hospitals, represents a major component of hazardous wastes generated in the U.S.. In f act, more than 4.5 million tons are generated per year. Hospital waste remediation was a 1.5 billion industry in 2003. Incineration remains th ...

DESCRIPTION (provided by applicant): We were originally awarded SBIR grant R43AT003183-01 in September 2005 to develop a miniature, wireless skin conductance monitor to measure hot flash frequency and severity. A prototype monitor was developed that measur es changes in sternal skin conductance and uses pattern recognition software to recognize the frequency, and timing of hot flashes. The electro ...

DESCRIPTION (provided by applicant): Persons with severe and persistent mental illness (SPMI) commonly experience both Substance Use Disorders (SUDs) and Borderline Personality Disorder (BPD), resulting in serious and complex personal costs and public heal th problems. Although Assertive Community Treatment (ACT) is efficacious for persons with SPMI, it is less clear the extent to which this appro ...

DESCRIPTION (provided by applicant): This is a Phase II Small Business Innovation Research (SBIR; R43/44) grant application to NIMH to support the further development and testing of an innovative, online training program in Panic Control Treatment for Adol escents (PCT-A). The current application represents a cooperative partnership between the PI's small business concern, Behavioral Tech Research ...

DESCRIPTION (provided by applicant): Interpersonal Psychotherapy (IPT) is one of the most thoroughly validated psychosocial treatments for depression. Dissemination of IPT, however, has been hindered by lack of trainers and didactic materials. Though sever al excellent textbooks regarding IPT are available, there are no other standardized educational materials or videotapes demonstrating specific ...

DESCRIPTION (provided by applicant): Methylation is a ubiquitous and reversible covalent modification used to control the function of diverse biomolecules including their activity, stability and localization. Like phosphorylation, methylation is used to mo dulate protein function, but in addition many small molecules are regulated by methylation including hormones, neurotransmitters, xenobiotics, ...

DESCRIPTION (provided by applicant): We propose applying innovative measurement technology to develop and disseminate a comprehensive function and disability assessment instrument for use in gerontological research and practice. This technology offers an e ffective method to resolve the classic conflict between practicality and psychometric adequacy faced by traditional standardized outcome measur ...

DESCRIPTION (provided by applicant): Our objective is to achieve a major advance in the technology used to assess disability in children and youth. Measurement and practical requirements for identifying disability and evaluating individual progress across pediatric age groups and care settings present a serious dilemma to current fixed-item survey instruments. In Phase I proposals, we have develo ...

DESCRIPTION (provided by applicant): The long-term objective of this proposed research is to develop a simple, inexpensive point-of-care device that will perform absolute and percent CD4+ T cell counts from whole blood. This will be accomplished by adaptin g and testing a novel hybrid approach to microfluidic sample preparation and analysis. One-time use thin-film laminated microfluidic cassette ...

DESCRIPTION (provided by applicant): Depression is a serious, debilitating disorder that affects millions of people, but treatment research is hampered by the limited reliability of current outcome measures that are often biased by a number of methodologic al and clinical factors. Such considerations resulted in the issuance of Program Announcement 06-016, Development of Biomarkers for Mental Hea ...