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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Control Electronics for Space-Qualified Cryogenic Coolers

    SBC: CREARE LLC            Topic: MDA17T003

    Future MDA space missions will utilize small spacecraft with correspondingly small, advanced sensor systems. Cooling of these sensors is required to decrease detector noise and increase detector sensitivity by maintaining the detector at a reduced operating temperature. The cooling system comprises a mechanical cryocooler and its control electronics, both of which are critical technologies to enab ...

    STTR Phase I 2018 Department of DefenseMissile Defense Agency
  2. Programmable Multi-Frequency Transmitter

    SBC: MAXENTRIC TECHNOLOGIES LLC            Topic: MDA16T005

    To meet the demands of the MDA16-T005 STTR solicitation, the MaXentric/UTK team proposes the MaXPMFT, which exploits a wideband software defined radio architecture to create a transmitter with programmable output frequency. The flexible system will provide the ideal solution for current and future missile flight test telemetry needs through its compatibility with nearly all missile platforms and s ...

    STTR Phase II 2018 Department of DefenseMissile Defense Agency
  3. GreenCare Interactive Guide for Knee Replacement Surgery

    SBC: PEER Technologies PLLC            Topic: NIA

    Project SummaryAbstract The goal of this Phase I work is to finish development of an innovative interactive app designed to help patients appropriately use total knee replacementTKRsurgery and provide support to achieve best outcomesTKR is highly effective for treating advanced osteoarthritis of the kneebut it has risksAppropriate use can be assured by engaging patients in a Shared Decision Making ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  4. Activating latent growth factors for cartilage regeneration

    SBC: INNOVATIVE ELEMENTS, LLC            Topic: NIA

    Project summary Articular cartilage lesions are prevalent disorders affecting millions of AmericansDeprived of spontaneous healing capacitycartilage lesions may further deteriorate and lead to the onset of osteoarthritisOAOA represents a leading cause of chronic disabilities in the U Sand ultimately warrants total joint arthroplastyA common aspiration in orthopedic medicine is to regenerate the da ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  5. Adaptable Pediatric Neurocognitive Assessment

    SBC: CREARE LLC            Topic: 103

    PROJECT SUMMARY ABSTRACTMillions of children around the globe are afflicted with conditions that can alter neuropsychological developmentincluding human immunodeficiency virusHIVtraumatic brain injuryTBIcerebral malariaand a host of other developmental and acquired diseases and disordersEarly assessment and intervention are critical in overcoming cognitive and developmental deficiencies and are in ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  6. Restoring Beta-lactam efficacy against methicillin-resistant Staphylococci

    SBC: Prokaryotics, Inc.            Topic: NIAID

    Methicillin resistant Staphylococcus aureusMRSAand methicillin resistant Staphylococcus epidermidisMRSEare a major cause of bloodstream infections in the hospital and in the communityIndeedMRSA remains the second leading cause of mortality by drug resistant bacterial pathogens in the USAAlthough two mechanistically novel antibiotic classes exist to treat such infectionsDaptomycinDAP and LinezolidL ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  7. Preparation and development of a stabilized C3 analog for the treatment of paroxysmal nocturnal hemoglobinemia

    SBC: Cascade Biotechnology            Topic: NHLBI

    Abstract We propose to develop analogs of human complement Cthat have the ability to form a stable CconvertaseIn additionthese proteins will be designed to decrease the affinity of the proteins for factor H bindingAll proteins will be expressed in the Baculovirus insect protein expression systemand tested for their ability to form a stable Cconvertase enzyme that is able to deplete complement in h ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  8. Antepartum tactile imager for minimizing risk of maternal childbirth trauma

    SBC: ADVANCED TACTILE IMAGING INC            Topic: NICHD

    Overof women suffer obstetric trauma to one or several components of the pelvic floorwith vaginaperineal bodylevator ani musclesand the anal sphincter complex affected most commonlyBirth injury to these integral structural components of the female pelvic floor leads to pelvic pain and dyspareuniaand serves as the most important and potentially modifiable risk factor for subsequent pelvic floor dis ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  9. pRBC Contaminant Removal with Hemocompatible Porous Polymer Beads

    SBC: CYTOSORBENTS MEDICAL INC            Topic: NHLBI

    Packed red blood cellpRBCtransfusions save livesHoweverhundreds of thousands of non hemolytic transfusion reactions occur each year worldwideranging from mild fever and pruritisto serious lifethreatening reactions such as severe hyperkalemiaanaphylaxisand transfusion related acute lung injuryTRALIMild moderate reactions drive patient discomfortdocumentationand testing costs while serious reactions ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  10. Development of CM-SV1, a monoclonal antibody treatment for Sudan Virus

    SBC: CELDARA MEDICAL, LLC            Topic: NIAID

    PROJECT SUMMARY The filovirusesfamily Filoviridaecomprising five ebolavirusesa cuevavirusand two Marburg virusesare negative strand RNA viruses that cause severe hemorrhagic fever with up tohuman case fatality rateTheepidemic in Western Africacaused by the Zaire ebolavirusEBOVspecies demonstrated the potential for these viruses to cause dire health emergencies of global scopeand highlighted the ne ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
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