Award Data

Improved head and hearing protection is required for aircraft maintainers working on a carrier flight deck during launch and recovery operations. Legacy Flight Deck Cranials are inadequate in many aspects including hearing protection, impact protection, cleaning, comfort, and compatibility with night vision devices (NVDs) and with chemical, biological, and radiological (CBR) equipment. In this p ...

ImmuNext has defined an anti-MCT1 monoclonal antibody (mAb) that will be developed for the treatment of human autoimmune disease. The membrane monocarboxylate nutrient transporter SLC16A1 (MCT1) is a multi-pass transmembrane protein responsible for the facilitated transport of critical metabolites, including products of glycolysis: lactate, pyruvate and ketones. Our strong preliminary data support ...

DESCRIPTION (provided by applicant): Improved understanding of the role of growth factors as biochemical mediators of wound healing has paved the way for a new family of bioactive therapeutic products to expedite wound healing. Delivery of growth factors ( recombinant or as autologous platelets) has emerged as a possible commercial opportunity for improving the clinical outcomes of soft, bone, and ...

The current use of polymer matrix composite materials aboard U.S. Navy ships has been limited to mainly exterior parts such as DDX topside structures, sonar bow domes, towed array fairings, diving planes, control surfaces and the prototype submarine sail dome for VA class submarines. There has been increasing interest in the development of composite materials for applications inside ships and sub ...

Diode-Pumped Alkali Lasers (DPALs) have great potential for high-energy lasers. Proper design of these systems is challenging because many interrelated processes impact their performance, and critical kinetic rate coefficients are not well known. In response, our team is developing a comprehensive physics-based analysis/design tool, and experimentally determining key kinetic rate coefficients. The ...

The T/R module development derives from and extends from a technology developed by North Star Scientific (NSS) in SBIR Phase III work on a LINK-16 high power amplifier. The T/R module effort initiates a radar electronics development to follow a multi-band antenna that is being developed for 21st century Navy surveillance needs.

The team proposes to use an analogous approach to the method previously developed and demonstrated under the Phase II/II.5 AFP-based trace TNT sensor. The technology developed under this Phase II will use an optically-interrogated (SERS) transducer in conjunction with a preconcentrating front-end sampling approach for the detection of RDX, PETN and HMX.

Improved head and hearing protection is required for aircraft maintainers working on a carrier flight deck during launch and recovery operations. Legacy Flight Deck Cranials are inadequate in many aspects including hearing protection and impact protection. In previous work, Creare has developed a Flight Deck Cranial (FDC) that offers unparalleled hearing protection and industrial standard head pro ...

The precision medicine initiative coupled with advances in genomic research and diagnostics isleading to vast increases in the volume of genomic data being createdwith some estimates statingit will outstrip the storage requirements of YouTube byEnsuring all this data can becost effectively managedand that experts from the biomedicalinformatics and medical disciplinescan easily collaborate on analy ...

DESCRIPTION (provided by applicant): In this translational SBIR program, we will develop a totally implantable, wireless, subdural electrode grid for short-term cortical EEG monitoring (less than 30 days). This device will be based upon novel manufacturin g processes that will allow synthesis of the wireless implants with integrated electronics at low cost and prices that are competitive with exi ...