Award Data

Abstract Type A and B Influenza viruses cause severe seasonal epidemics and less frequent but more deadly pandemic infectionsVaccination provides the best protectionalthough serious problems are confronting the global Influenza marketVirus diversity and mutation rates necessitate the annual production of hundreds of millions of vaccines using antiquated egg based technologiesCompounding this is th ...

Project Summary SignificanceSinceavian influenza AH Nhas sickened overpeople with amortality rateHalf of all cases occurred inwhich also saw the emergence of a highly pathogenic strainThusH Navian influenza is poised to emerge as a devastating pandemic in a worldwide population that has no pre existing immunityCurrent Hvaccineswhether attenuatedinactivatedsplit or recombinantare insufficiently imm ...

PROJECT SUMMARYCreare and its clinical and research partners propose to develop a software platformOnTRACKOnline Treatment Recovery Assistance for Concussion in Kidsfor children and adolescents recovering from concussion or mild traumatic brain injurymTBIThe platform includes a mobile applicationappfor the patients and their care teamparentsteacherscoachesetca database serverand a decision support ...

Mentis Sciences Inc. (Mentis) proposes to develop a refurbishment program that is capable of disassembling, inspecting, and re-building complex systems and components, with the initial system of focus being the Minuteman Missile Antenna/Antenna Pedestal Assembly.To become a refurbishment supplier, Mentis will develop and adapt inhouse processes for performing refurbishment services by leveraging c ...

The Defense Logistics Agency (DLA) top priority is warfighter support, and the DLA is firmly committed to a robust counterfeit mitigation strategy that protects our warfighters and the vital missions they perform. HNu Photonics, LLC (HNu) Color Holographic Quick Response (CHQR, pronounced “Checker”) technology combines RGB 3-layer QR codes with holographic imaging technology, and is as robust ...

Having previously designed, built and successfully tested a Rotating Detonation Rocket Engine (RDRE), GHKN Engineering proposes to evaluate the feasibility of RDRE technology for boost or upper stage propulsion for launch of small satellites to LEO. RDREs represent an innovative new rocket technology that harnesses the potential of continuous detonation combustion in elegant, compact, annular desi ...

A high-fidelity RF/Analog fiber-optic link based on a balanced photodetection using a dual-output modulator and a balanced photodetector pair offers significant improvement in RF gain, low noise figure (NF) and enhanced spur-free dynamic range (SFDR). It requires the use of path-length matched dual fibers to achieve proper noise cancellation. The objective for this SBIR is to develop a balanced fi ...

Diode-Pumped Alkali Lasers (DPALs) have great potential for high-energy lasers. Proper design of these systems is challenging because many interrelated processes impact their performance, and critical kinetic rate coefficients are not well known. In response, our team is developing a comprehensive physics-based analysis/design tool, and experimentally determining key kinetic rate coefficients. The ...

Creare is proposing to develop a heater utilizing carbon nanotubes (CNTs) that will have high temperature uniformity and high optical transmission with low glare. By creating a variable effective sheet resistance across the windshield, we will be able to produce a robust design that can be flexed and easily scaled up to a production environment. In Phase I, we will fabricate and test a coupon size ...

PROJECT SUMMARY Failure of new drugs at late stages of development is an extremely costly event commonly associated with the detection of unexpected arrhythmogenic properties in novel drugs Undetected arrhythmia inducing effects are also a common reason for drug withdrawal from the market As a result the FDA now mandates that all new drugs be tested for potential arrhythmogenic properties which ha ...