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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Development of novel small molecule analgesics modulating the nNOS-NOS1AP protein-protein interaction

    SBC: ANAGIN            Topic: 103

    Abstract This applicationDevelopment of novel small molecule analgesics modulating the nNOS NOS AP proteinprotein interactionaddresses the critical need for more effective medications to treat chronic neuropathic pain affectingmillion people in the United StatesCurrent pain medications such as NSAIDSsteroidsopiates and gabapentin analogs have documented and often severe side effectsare poorly effe ...

    SBIR Phase II 2018 Department of Health and Human Services
  2. OnTRACK: Mobile Application for Pediatric Post-TBI Patient Management

    SBC: CREARE LLC            Topic: NCIPC

    PROJECT SUMMARYCreare and its clinical and research partners propose to develop a software platformOnTRACKOnline Treatment Recovery Assistance for Concussion in Kidsfor children and adolescents recovering from concussion or mild traumatic brain injurymTBIThe platform includes a mobile applicationappfor the patients and their care teamparentsteacherscoachesetca database serverand a decision support ...

    SBIR Phase I 2018 Department of Health and Human Services
  3. Optimization of small molecule SERCA2b activators to inhibit neuron loss in Alzheimer's disease

    SBC: Neurodon LLC            Topic: NIA

    Alzheimer s diseaseADis an immense national public health burdenIt is theth leading cause of death in the US with overmillion Americans sufferingand costs of over $billion in health care and related expensesThis patient population is expected to almost triple over the nextyearsDespite this urgent needthere are currently no disease modifying agents approvedNeuron loss is the only physiological phen ...

    STTR Phase I 2018 Department of Health and Human Services
  4. Tissue Oxygenation in Small Retinal Vessels

    SBC: Aeon Imaging, LLC            Topic: W

    Summary Recentlywe found extensive remodeling of the microvasculature of the retinaoccurring in some diabetic patients much earlier than expectedThis provides the potential for novel biomarkers to improve classification of patients for management and cost effective testing of therapiesHoweverthe equipment is too expensive for most clinics and small practicesThese early retinal microvascular change ...

    STTR Phase I 2018 Department of Health and Human Services
  5. Increase Product Availability And Improve Life Cycle Support For MILSATCOM System Components

    SBC: Mentis Sciences, Inc.            Topic: DLA182005

    Mentis Sciences Inc. (Mentis) proposes to develop a refurbishment program that is capable of disassembling, inspecting, and re-building complex systems and components, with the initial system of focus being the Minuteman Missile Antenna/Antenna Pedestal Assembly.To become a refurbishment supplier, Mentis will develop and adapt inhouse processes for performing refurbishment services by leveraging c ...

    SBIR Phase I 2018 Department of DefenseDefense Logistics Agency
  6. Reduced Cavitation, High Efficiency Outboard Propulsors for Small Planing Craft

    SBC: CANDENT TECHNOLOGIES INCORPORATED            Topic: N17AT019

    The Candent Technologies Reduced Cavitation, High Efficiency Outboard Propulsor for Small Planing Craft Phase II program is structured to develop an advanced waterjet propulsor for the Combat Rubber Raiding Craft (CRRC). This new axial flow waterjet propulsion system is designed as a bolt on assembly that replaces the lower unit of the existing MFE 55 outboard motor. This new propulsion system inc ...

    STTR Phase II 2018 Department of DefenseNavy
  7. Green Monopropellant Thruster TRL Maturation Scaling Effort

    SBC: CREARE LLC            Topic: MDA12T008

    Diode-Pumped Alkali Lasers (DPALs) have great potential for high-energy lasers. Proper design of these systems is challenging because many interrelated processes impact their performance, and critical kinetic rate coefficients are not well known. In response, our team is developing a comprehensive physics-based analysis/design tool, and experimentally determining key kinetic rate coefficients. The ...

    STTR Phase II 2018 Department of DefenseMissile Defense Agency
  8. Carbon Nanotube Windshield Heater

    SBC: CREARE LLC            Topic: N182103

    Creare is proposing to develop a heater utilizing carbon nanotubes (CNTs) that will have high temperature uniformity and high optical transmission with low glare. By creating a variable effective sheet resistance across the windshield, we will be able to produce a robust design that can be flexed and easily scaled up to a production environment. In Phase I, we will fabricate and test a coupon size ...

    SBIR Phase I 2018 Department of DefenseNavy
  9. Non-surgical treatment option for pelvic organ prolapse

    SBC: Reia, LLC            Topic: NICHD

    Project SummaryAbstract Reia is working to address a prevalent gynecological conditionpelvic organ prolapsePOPwhich affects more thanof women over the age ofPOP occurs when the pelvic floor connective tissue and muscles weakenallowing the uterus or vaginal walls to descendIn extreme casesthe uterus descends through the opening of the vagina and hangs outside of the bodyPOP can be treated non surgi ...

    SBIR Phase I 2018 Department of Health and Human Services
  10. Smart Cavity Creator Drill for Lumbar Interbody Fusion

    SBC: PEER Technologies PLLC            Topic: NIBIB

    PROJECT SUMMARYABSTRACT Older patients with persistent and progressive symptoms of chronic back pain and leg pain often have a diagnosis of lumbar degenerative spondyolisthesis and undergo complex lumbar decompression and fusion surgeryOverof these procedures are performed in the United States each yearSurgery is highly effective but technically challengingOne technical challenge of fusion in spon ...

    SBIR Phase I 2018 Department of Health and Human Services

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