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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Non-surgical treatment option for pelvic organ prolapse

    SBC: REIA LLC            Topic: NICHD

    Project SummaryAbstract Reia is working to address a prevalent gynecological conditionpelvic organ prolapsePOPwhich affects more thanof women over the age ofPOP occurs when the pelvic floor connective tissue and muscles weakenallowing the uterus or vaginal walls to descendIn extreme casesthe uterus descends through the opening of the vagina and hangs outside of the bodyPOP can be treated non surgi ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  2. Preparation and development of a stabilized C3 analog for the treatment of paroxysmal nocturnal hemoglobinemia

    SBC: Cascade Biotechnology            Topic: NHLBI

    Abstract We propose to develop analogs of human complement Cthat have the ability to form a stable CconvertaseIn additionthese proteins will be designed to decrease the affinity of the proteins for factor H bindingAll proteins will be expressed in the Baculovirus insect protein expression systemand tested for their ability to form a stable Cconvertase enzyme that is able to deplete complement in h ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Smart Cavity Creator Drill for Lumbar Interbody Fusion

    SBC: PEER Technologies PLLC            Topic: NIBIB

    PROJECT SUMMARYABSTRACT Older patients with persistent and progressive symptoms of chronic back pain and leg pain often have a diagnosis of lumbar degenerative spondyolisthesis and undergo complex lumbar decompression and fusion surgeryOverof these procedures are performed in the United States each yearSurgery is highly effective but technically challengingOne technical challenge of fusion in spon ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  4. Development and Validation of a Platform to Assess and Improve Barriers to Health for Digitally Underserved Populations

    SBC: Responsive Health, Inc.            Topic: 102

    Project SummaryInflammatory bowel diseaseIBDis a chronic disabling disease that leads to poor quality of life among otherwise young healthy adultsUnderserved and minority populations bear a higher disease burden with more hospitalizations and less use of gastroenterology specialty care and of maintenance medications to prevent flaresThe goal of this proposalDevelopment and Validation of a Platform ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  5. TrachAlarm: A novel, low-cost accessory to automatically detect and alert caregivers to tracheostomy tube decannulation

    SBC: INNOVATIONS UNLIMITED LLC            Topic: NINR

    ABSTRACT The objective of the Phasegrant is to designdevelopand demonstrate feasibility of TrachAlarma novellow cost accessory to automatically detect and alert caregivers when a tracheostomy tube has become accidentally removed from the patientTracheostomy provides a criticallife supporting function for overmillion individuals in the United States with overnew procedures performed each yearEach o ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  6. Supine Breast MRI Standardization for Breast Cancer Locator

    SBC: CAIRNSURGICAL, INC.            Topic: 102

    PROJECT SUMMARY ABSTRACTCairnSurgicalInca Dartmouth spin off companywill standardize supine breast MRI to streamline production of the Breast Cancer LocatorBCLas a cancer localization device for use in breast conserving surgeryBCStoieliminate wire localizationa moderately effectivesomewhat costly and certainly inconvenient procedure for patients and surgeonsand concomitantly toiireduce positive ma ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  7. Rapid, quantitative and affordable point-of-care diagnostics for oral and oropharyngeal cancer

    SBC: SUMMIT BIOMEDICAL IMAGING LLC            Topic: 102

    Project Summary Abstract This proposal seeks to develop and validate a novel technology for detecting malignant cells in biospecimen samples of oral and oropharyngeal cancerThis technology will allow screeningdiagnosisand quantification at higher precision and lower cost than what is currently availableIn the USboth the incidence and societal impact of oropharyngeal cancer are increasingdespite th ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  8. Adenylyl Cyclase Type 5 Inhibition to Treat Myocardial Infarction

    SBC: VASADE BIOSCIENCES, INC.            Topic: NHLBI

    PROJECT SUMMARY ABSTRACT The most significant advance in the treatment of Myocardial InfarctionMIhas been reperfusion therapywhich must be applied immediately after the MI diagnosis has been madeDespite the thousands of studies on drug therapies designed to reduce the size of the MImost have failed in clinical trialsOur hypothesis is that a major reason why these drugs failed is that they must be ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  9. Nanoparticle Probes to Objectively Measure Pain Following Back Surgery

    SBC: PEER Technologies PLLC            Topic: NIDA

    AbstractPost operative pain is poorly managed and increases risk for delayed recoverychronic painopioid dependenceand persistent disabilityOne barrier to effective management of acute pain is the absence of objective measuresWe propose to conduct a feasibility study for technology to objectively measure postoperative painWe have selected back surgery as a model given its frequencycostand poor outc ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  10. Novel SUMO Activators for the Treatment of Duchenne Muscular Dystrophy-Associated Heart Failure

    SBC: SUMOCOR LLC            Topic: NHLBI

    PROJECT SUMMARY Our objective is to develop a small molecule therapy for the treatment of heart disease associated with Duchenne Muscular DystrophyDMDa disease that occurs inout of everymale birthsand for which there is no cure or long term effective treatmentHeart failureHFis a contributing cause of mortality among persons afflicted with DMDA key abnormality in HF is defective handling of calcium ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
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