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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A Low-Cost and Convenient Solution for Hearing Aid Shell Manufacturing

    SBC: Xyken, LLC            Topic: R

    Project SummaryWe propose in this SBIR effort to develop a mobile platform basedlow costyet highly accurateD scanner for audiologists or dispensers to quickly capture ear structure and locally optimize custom fit hearing aid shell design through rapid prototypingHearing loss is the third most prevalent chronic health condition facing seniorsUntreated hearing loss has been shown to lead to physical ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  2. Novel whole-genome analysis methods for Alzheimer's risk prediction

    SBC: PARABON NANOLABS, INC.            Topic: NIA

    Project Summary AbstractAlzheimerandapos s DiseaseADaffects millions of Americansyet there are no treatments that meaningfully affect disease progression once symptoms manifestThis has shifted the focus to early detection and interventionwhich is thought by many researchers to offer the best chance of slowing or stopping the progression of ADHowevertrials aimed at averting the underlying causes of ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Knee Biofeedback Rehabilitation Interface for Game-based Home Therapy (KneeBRIGHT)

    SBC: BARRON ASSOCIATES, INC.            Topic: NIA

    PROJECT SUMMARY ABSTRACT SignificanceThe Knee Biofeedback Rehabilitation Interface for Game based Home TherapyKneeBRIGHTsystem combines electromyographyEMGbiofeedback with video game therapyVGTto provide knee osteoarthritisOApatients with an engagingeffective tool for conducting rehabilitation exercises at homeKneeBRIGHT aims to motivate patients with knee OA to conduct regular muscle strengthenin ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  4. Smartphone phenotype collection for diagnostic screening of mild cognitive impairment

    SBC: PARABON NANOLABS, INC.            Topic: NIA

    Project Summary This project addresses a critical need for early detection of mild cognitive impairment (MCI) and other Alzheimer's-related dementias (ADRD). Advances in smartphone hardware, computer vision, and machine learning have enabled the possibility of producing smartphone-based cognitive testing applications able to collect electronic sensor data and transform it into highly informative ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  5. High-throughput nanoMEA-based Proarrhythmia Assay

    SBC: CURI BIO, INC.            Topic: NHLBI

    PROJECT SUMMARY Failure of new drugs at late stages of development is an extremely costly event commonly associated with the detection of unexpected arrhythmogenic properties in novel drugs Undetected arrhythmia inducing effects are also a common reason for drug withdrawal from the market As a result the FDA now mandates that all new drugs be tested for potential arrhythmogenic properties which ha ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  6. Non-surgical treatment option for pelvic organ prolapse

    SBC: REIA LLC            Topic: NICHD

    Project SummaryAbstract Reia is working to address a prevalent gynecological conditionpelvic organ prolapsePOPwhich affects more thanof women over the age ofPOP occurs when the pelvic floor connective tissue and muscles weakenallowing the uterus or vaginal walls to descendIn extreme casesthe uterus descends through the opening of the vagina and hangs outside of the bodyPOP can be treated non surgi ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  7. Development and evaluation of an internet based adaptation of the New Beginnings Program for divorced parents

    SBC: Family Transitions- Programs that Work, LLC            Topic: NICHD

    PROJECT ABSTRACT The proposed research builds on a successful Phase I SBIR grant to develop and test a web based version of a parenting after divorce group interventionthe New Beginnings Programwhich has been shown in two randomized trials to reduce youthsproblem behaviors and enhance their developmental competencies in theyear period after their parents participatedThe proposed web based format w ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  8. Novel radiometry-guided ablation catheter to treat resistant hypertension or CKD

    SBC: Symple Surgical Inc            Topic: R

    PROJECT SUMMARY Increased renal sympathetic activity is a causal pathogenetic mechanism of both cardiovascular hypertension and progressive loss of renal function in patients with chronic kidney diseaseCKDIn millions of patients with resistant hypertensiondependable thermal disruption of targeted renal sympathetic nerves can reduce blood pressure and ultimately prevent heart diseasestroke and kidn ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  9. 4D Acoustoelectric Cardiac Imaging for Fast and Accurate Mapping of Arrhythmias

    SBC: ElectroSonix LC            Topic: NHLBI

    Abstract Despite global success of interventional cardiac surgery for treatment of arrhythmias, electroanatomical mapping (EAM) of the heart has significant drawbacks. The procedure is slow and prone to registration errors, largely ineffective for treating transient arrhythmias, such as ventricular tachycardia, and exhibits relatively poor spatial resolution. With only a 50% success rate for first ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  10. Preparation and development of a stabilized C3 analog for the treatment of paroxysmal nocturnal hemoglobinemia

    SBC: Cascade Biotechnology            Topic: NHLBI

    Abstract We propose to develop analogs of human complement Cthat have the ability to form a stable CconvertaseIn additionthese proteins will be designed to decrease the affinity of the proteins for factor H bindingAll proteins will be expressed in the Baculovirus insect protein expression systemand tested for their ability to form a stable Cconvertase enzyme that is able to deplete complement in h ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
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