Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Synthetic Universal Flu Vaccine

    SBC: TRIA BIOSCIENCE CORP.            Topic: NCIRD

    Abstract Type A and B Influenza viruses cause severe seasonal epidemics and less frequent but more deadly pandemic infectionsVaccination provides the best protectionalthough serious problems are confronting the global Influenza marketVirus diversity and mutation rates necessitate the annual production of hundreds of millions of vaccines using antiquated egg based technologiesCompounding this is th ...

    SBIR Phase I 2018 Department of Health and Human Services
  2. Engineering Nanoparticle Alum Adjuvants for Pandemic Influenza Vaccines

    SBC: HDT Bio Corp.            Topic: NCIRD

    Project Summary SignificanceSinceavian influenza AH Nhas sickened overpeople with amortality rateHalf of all cases occurred inwhich also saw the emergence of a highly pathogenic strainThusH Navian influenza is poised to emerge as a devastating pandemic in a worldwide population that has no pre existing immunityCurrent Hvaccineswhether attenuatedinactivatedsplit or recombinantare insufficiently imm ...

    SBIR Phase I 2018 Department of Health and Human Services
  3. OnTRACK: Mobile Application for Pediatric Post-TBI Patient Management

    SBC: CREARE LLC            Topic: NCIPC

    PROJECT SUMMARYCreare and its clinical and research partners propose to develop a software platformOnTRACKOnline Treatment Recovery Assistance for Concussion in Kidsfor children and adolescents recovering from concussion or mild traumatic brain injurymTBIThe platform includes a mobile applicationappfor the patients and their care teamparentsteacherscoachesetca database serverand a decision support ...

    SBIR Phase I 2018 Department of Health and Human Services
  4. Gene and Stem Cell-Based Treatment for Tendinopathy

    SBC: NEW YORK R&D CENTER FOR TRANSLATIONAL MEDICINE AND THERAPEUTICS, INC.            Topic: R

    Project SummaryTendinopathy is a common chronic tendon disorder that affectsof individuals overyears oldIt is characterized by painswellingloss of functionand impaired performanceThere is currently no cure for tendinopathySpontaneous repair or treatment typically leads to scar formationresulting in a weakened tissue with reduced function and mechanical properties that may ultimately rupture with f ...

    SBIR Phase I 2018 Department of Health and Human Services
  5. Scale-up and Synthesis of a Tau Oligomer Inhibitor to initiate IND enabling studies for AD and ADRD

    SBC: Oligomerix, Inc.            Topic: NIA

    PROJECT SUMMARYSBIR RRFast Track ApplicationFOA NumberPASThe long term goal of this program is to develop a disease modifyingsmall molecule drug for Alzheimer s diseaseADand AD related dementiasADRDwith tau pathologyThere is a critical unmet need for a disease modifying drugDMDfor ADChronic treatment strategies require safeeffectiveand economically feasible approaches such as small molecule drugsT ...

    SBIR Phase I 2018 Department of Health and Human Services
  6. Non-surgical treatment option for pelvic organ prolapse

    SBC: Reia, LLC            Topic: NICHD

    Project SummaryAbstract Reia is working to address a prevalent gynecological conditionpelvic organ prolapsePOPwhich affects more thanof women over the age ofPOP occurs when the pelvic floor connective tissue and muscles weakenallowing the uterus or vaginal walls to descendIn extreme casesthe uterus descends through the opening of the vagina and hangs outside of the bodyPOP can be treated non surgi ...

    SBIR Phase I 2018 Department of Health and Human Services
  7. Development of an advanced cryothermal ablation catheter and method for treating cardiac arrhythmias

    SBC: CELL PRESERVATION SERVICES INC            Topic: R

    The need for the development of new strategies for treatment of cardiac arrhythmiasincluding ventricular arrhythmiashas experienced a palpable increase in the last few yearsVentricular ArrhythmiaVAor ventricular tachycardiaVTis a severe abnormal heart rhythm which can cause death if not treated immediatelyVentricular FibrillationVFis the most serious form of VAVF is most commonly caused by VT and ...

    SBIR Phase I 2018 Department of Health and Human Services
  8. Preparation and development of a stabilized C3 analog for the treatment of paroxysmal nocturnal hemoglobinemia

    SBC: Cascade Biotechnology            Topic: NHLBI

    Abstract We propose to develop analogs of human complement Cthat have the ability to form a stable CconvertaseIn additionthese proteins will be designed to decrease the affinity of the proteins for factor H bindingAll proteins will be expressed in the Baculovirus insect protein expression systemand tested for their ability to form a stable Cconvertase enzyme that is able to deplete complement in h ...

    SBIR Phase I 2018 Department of Health and Human Services
  9. Smart Cavity Creator Drill for Lumbar Interbody Fusion

    SBC: PEER Technologies PLLC            Topic: NIBIB

    PROJECT SUMMARYABSTRACT Older patients with persistent and progressive symptoms of chronic back pain and leg pain often have a diagnosis of lumbar degenerative spondyolisthesis and undergo complex lumbar decompression and fusion surgeryOverof these procedures are performed in the United States each yearSurgery is highly effective but technically challengingOne technical challenge of fusion in spon ...

    SBIR Phase I 2018 Department of Health and Human Services
  10. Transforming STEM Education in K-12 using the Biological Interactive Outcomes Modular Environment (BIOME)

    SBC: IQ Smart Interactive LLC            Topic: 500

    PROJECT SUMMARYThe United States is falling behind in Science and Math according to results from the Programme for International Student AssessmentPISAranking the US asth in Science andth in Mathematics out ofcountriesThese unfortunate statistics could be attributed to teacher hesitations in teaching math and scienceinability to excite student interest in STEM subjectsor an unclear real world appl ...

    SBIR Phase I 2018 Department of Health and Human Services
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