Award Data

This effort will augment the capabilities of an existing all reflecting, confocal FTIR microscope to allow for digital holographic imaging as wellspectral content determination at video frame rates. The use of a dual beam frequency comb, with a beam path coincident with the pathrequired for the digital holographic imaging, will allow spectral determination of any organism being holographically ima ...

Next-generation high-performance computing (HPC) hardware, such as the Intel Xeon Phi Knights Landing Many-Integrated-Core processor, provide new deep memory architectures that offer the promise of increased performance. The challenge in taking full advantage of this architecture is selecting which data structures will be placed in the high-bandwidth memory. Optimizing data structure placement in ...

Infrasound and seismic measurements are used by DTRA and the DoD for nuclear test monitoring, terrorist blast forensics, battle damage assessment, and environmental monitoring. However, these long wavelength physical signals are typically recorded through single-point sensors or sparse low density arrays. As a result, the critical signals of interest are often corrupted or masked by noise or inter ...

A significant performance gap exists between the theoretical number of Floating Point Operations (FLOPS) that a HPC machine is capable of sustaining and the number of FLOPS realized by real-world HPC applications. One of the principle reasons for this gap is the parasitic work that computational processes must do to communicate with one another. It has been shown that this communication work can b ...

This program plans to develop a drug delivery system that provides maximum oxime drug exposure and improve cholinesterase reactivation in the brain and tissues of central nervous system (CNS) of a warfighter after exposure to organophosphate (OP) poisoning. The greatest need for improvement in cholinesterase reactivation is the ability to deliver charged cholinesterase reactivators to the CNS tha ...

Organophosphorus chemical warfare nerve agents (OP-CWA) are attractive to terrorist groups and rogue states as an inexpensive and accessible technology for chemical warfare. OP-CWA and organophosphate pesticides cause severe neurological symptoms and death by inhibiting the enzyme acetylcholinesterase (AChE); the resulting excess acetylcholine accumulates and overstimulates the human or animal bo ...

PNTS proposes to develop a truly novel implementation of eye-safe terahertz (THz) spectroscopy that is unprecedented in the standoff detection regime for accuracy, low cost, and portability. PNTS has teamed with SC&A, Inc., and researchers from the University of Memphis to create a world class team of research and development personnel. We are proposing a continuous wave terahertz (THz-CW) spect ...

We propose a new active optical method to measure time-domain waveform of THz pulse in the vicinity of the target in an omni-directional manner. This method utilizes the THz radiation-enhanced-emission-of-fluorescence from laser-induced air plasma to detect the THz field, which enables the standoff sensing for low volatility chemicals using THz spectroscopy. We have demonstrated its capability of ...

Analysis of nuclear material samples in the field has many advantages over laboratory analysis. Laboratory analyses can be slow, involve increased expense, lead to additional waste generation and disposal problems, and may introduce errors due to sample degradation or mishandling. In situ analysis mitigates all of these problems. The specific aim of this project is the development of a truly por ...

A new type of compact induction accelerator currently under development at the Lawrence Livermore National Laboratory (LLNL) promises to increase the average accelerating gradient by at least an order of magnitude over that of existing induction machines. The machine is based on the use of high gradient vacuum insulators and advanced dielectric materials and switches. The system, called the Diel ...