Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. An Automated Early Motor Development Risk Screener from Observational Video Recordings of Infants and Toddlers

    SBC: BSolutions Inc            Topic: NICHD

    Motor development plays a pivotal role in an infant s overall development and has a cascading effect on socialcognitivememoryand language abilityThese functions can be compromised when motor development is disruptedmotor disruption is associated with generalized developmental delaysEarly screening and identification of delays can allow early interventions with the goal of not just improving motor ...

    SBIR Phase II 2018 Department of Health and Human Services
  2. pRBC Contaminant Removal with Hemocompatible Porous Polymer Beads

    SBC: CytoSorbents Medical Inc.            Topic: NHLBI

    Packed red blood cellpRBCtransfusions save livesHoweverhundreds of thousands of non hemolytic transfusion reactions occur each year worldwideranging from mild fever and pruritisto serious lifethreatening reactions such as severe hyperkalemiaanaphylaxisand transfusion related acute lung injuryTRALIMild moderate reactions drive patient discomfortdocumentationand testing costs while serious reactions ...

    SBIR Phase II 2018 Department of Health and Human Services
  3. Improved cleaning technology for reducing risk of transmitting infection in endoscopy.

    SBC: ADVANCED BIODEVICES, LLC            Topic: R

    Project Summary AbstractOutbreaks of infection caused by contaminated endoscopes are a serious public health problem that has even resulted in patient deathsCurrentlybecause of the narrowness of the channels and complexity of the endoscopethere simply is no reliable way of achieving thisThe existing cleaning protocols also are highly dependent on operator techniqueAccordinglythis is an urgent publ ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  4. Optimization and Validation of an indicator cell assay for blood-based diagnosis of lung cancer

    SBC: PreCyte Inc            Topic: 102

    Project SummaryThe Indicator Cell Assay PlatformiCAPis an inexpensive blood based assay that can be used for early detection of diseasedisease stage stratificationprognosis and response to therapy for a variety of diseasesThe iCAP uses culturedstandardized cells as biosensorscapitalizing on the ability of cells to respond to disease signals present in serum with exquisite sensitivityas opposed to ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  5. Targeting leukocyte metabolism to treat human autoimmune disease

    SBC: Immunext, Inc.            Topic: R

    ImmuNext has defined an anti MCTmonoclonal antibodymAbthat will be developed for the treatment of human autoimmune diseaseThe membrane monocarboxylate nutrient transporter SLCAMCTis a multi pass transmembrane protein responsible for the facilitated transport of critical metabolitesincluding products of glycolysislactatepyruvate and ketonesOur strong preliminary data support the tenet that mAbs tha ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  6. pRBC Contaminant Removal with Hemocompatible Porous Polymer Beads

    SBC: CytoSorbents Medical Inc.            Topic: NHLBI

    Packed red blood cellpRBCtransfusions save livesHoweverhundreds of thousands of non hemolytic transfusion reactions occur each year worldwideranging from mild fever and pruritisto serious lifethreatening reactions such as severe hyperkalemiaanaphylaxisand transfusion related acute lung injuryTRALIMild moderate reactions drive patient discomfortdocumentationand testing costs while serious reactions ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  7. Novel Methodology for Identification of Senolytics that Reduce Age-related Disease and Dysfunction

    SBC: Recursion Pharmaceuticals, LLC            Topic: NIA

    DESCRIPTIONprovided by applicantChronic diseases of aging account for a significant proportion of healthcare spending and result in a painful and limiting existence for many tens of millions of Americans and hundreds of millions of people around the worldRecursion Pharmaceuticals has developed a drug discovery platform that re purposes known drugs for the treatment of such diseasesThe platform con ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  8. Optimization and Validation of an Indicator Cell Assay for Blood-Based Diagnosis of Alzheimer's Disease

    SBC: PreCyte Inc            Topic: NIA

    Project SummaryPreCyte is developing the Indicator Cell Assay PlatformiCAPas a broadly applicable and inexpensive blood based assay that can be used for the early detection of diseasedisease stage stratificationprognosis and predicting response to therapy for a variety of diseasesThe iCAP uses culturedstandardized cells as biosensorscapitalizing on the ability of cells to respond to disease signal ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  9. Painless Defibrillation

    SBC: Coridea, LLC            Topic: NHLBI

    Project SummaryThe purpose of the proposed work is first in man testing of novel painless defibrillationPaDetherapySudden cardiac arrestSCAremains the number one killer in western civilizationThe underlying mechanism of SCA is usually ventricular fibrillationVFand survival depends on prompt defibrillationExisting defibrillators rely on the delivery of a brief high voltage shock to the heartWhile t ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  10. Development of Anti-ceramide scFv as Mitigator of the Radiation GI Syndrome

    SBC: Ceramedix Holding, LLC            Topic: NIAID

    Project Summary Abstract Inhibition of ceramide protects mice from death from the Radiation GI SyndromeRGSAdministration of anticeramide single chain FvscFvh post radiation exposure increases survival in intestinal stem cells and dramatically improves overall survival in miceThese data indicate that anti ceramide scFv represents the first effective mitigator of lethal RGSTo advance the development ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
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